Zerodol Pg 200/75 Mg Tablet (10 Tab)

ZERODOL PG 200/75 MG TABLET

ZERODOL PG 200/75 MG TABLET, also known as Zerodol-PG 200/75 Tablet SR, is a prescription medication manufactured by Ipca Laboratories Ltd..

Composition Each tablet contains a combination of two active ingredients: Aceclofenac 200 mg (Sustained Release) and Pregabalin 75 mg. Aceclofenac is a non-steroidal anti-inflammatory drug (NSAID) that works by blocking chemical messengers responsible for pain and inflammation. Pregabalin is an anticonvulsant that calms damaged or overactive nerves, thereby reducing pain signals.

Uses ZERODOL PG 200/75 MG TABLET is primarily used for the management of neuropathic pain, which is chronic nerve pain caused by nerve damage or a malfunctioning nervous system. This includes sensations such as burning, throbbing, sharp, numbness, and pins and needles pain. It is also prescribed for:

• Joint pain (e.g., osteoarthritis, rheumatoid arthritis, ankylosing spondylitis).
• Back pain, including chronic back pain with nerve involvement.
• Neck pain.
• Sciatic nerve pain.
• Post-surgical or injury-related pain.
• Diabetic neuropathy and post-herpetic neuralgia.

Dosage and Administration ZERODOL PG 200/75 MG TABLET should be taken exactly as prescribed by a physician. Typically, it is advised to take one tablet daily, preferably with or after meals to minimize stomach upset. The tablet should be swallowed whole with a glass of water and not chewed, crushed, or broken. The duration of treatment will be determined by the doctor based on the patient's medical condition.

Side Effects Common side effects may include:

• Nausea, vomiting, indigestion, stomach pain, diarrhea, constipation, heartburn.
• Dry mouth, loss of appetite.
• Dizziness, drowsiness, sleepiness, tiredness.
• Blurred vision, uncoordinated body movements.
• Weight gain.
• Headache, lack of attention, memory impairment.
• Muscle cramps, joint or back pain.

Serious side effects are rare but may include suicidal tendencies (consult a doctor immediately if experienced) and a decrease in sperm count, potentially affecting fertility in men (due to Pregabalin).

Precautions

• Pregnancy and Breastfeeding: Not recommended for use in pregnant or breastfeeding women unless prescribed by a doctor after careful consideration of benefits versus risks.
• Alcohol: Avoid consuming alcohol as it can increase drowsiness, dizziness, and the risk of stomach problems.
• Driving and Operating Machinery: This medicine can cause dizziness, drowsiness, and blurred vision; therefore, avoid driving or operating machinery if you are not alert.
• Pre-existing Conditions: Inform your doctor if you have a history of heart disease, severe kidney disease, liver problems, stomach ulcers, GI bleeding, bipolar syndrome, porphyria, diabetes, asthma, hypertension, high blood cholesterol, inflammatory bowel diseases, blood clots, bleeding disorders, or a history of stroke or recent bypass surgeries.
• Children: ZERODOL PG 200/75 MG TABLET is not recommended for use in children as its safety and effectiveness have not been established.
• Abrupt Discontinuation: Do not stop taking the medicine without consulting your doctor, as it may lead to withdrawal symptoms.

Storage Store in a cool and dry place, away from direct sunlight. Keep out of the sight and reach of children.

ZERODOL PG 200/75 MG TABLET is a combination medication containing Aceclofenac (200mg) and Pregabalin (75mg), primarily used to manage various types of pain, especially those with a neuropathic component.

What is ZERODOL PG 200/75 MG TABLET used for?

ZERODOL PG 200/75 MG TABLET is primarily used for the management of neuropathic pain, which is chronic nerve pain caused by nerve damage or dysfunction. This includes conditions such as diabetic neuropathy, post-herpetic neuralgia (pain after shingles), sciatica, and chronic back pain with nerve involvement. It is also effective for joint pain related to conditions like osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, neck pain, and pain following surgery or injury.

How does ZERODOL PG 200/75 MG TABLET work?

This medicine combines two active ingredients: Aceclofenac and Pregabalin. Aceclofenac is a non-steroidal anti-inflammatory drug (NSAID) that works by blocking the action of cyclooxygenase (COX) enzymes, which are responsible for producing prostaglandins that cause pain and inflammation. Pregabalin is an anticonvulsant that helps calm damaged or overactive nerves in the brain and spinal cord by modulating calcium channels in nerve cells, thereby reducing pain signals. Together, they provide comprehensive pain relief by targeting both inflammatory and nerve-related pain pathways.

What is the usual dosage for ZERODOL PG 200/75 MG TABLET?

The typical dosage is generally one tablet daily. It is recommended to take the tablet with or after food to prevent stomach upset. The tablet should be swallowed whole with a glass of water, without chewing, crushing, or breaking it. Your doctor will determine the appropriate dose and duration based on your age, weight, medical condition, and response to treatment. Do not alter the dosage or duration of treatment without consulting your doctor.

What are the possible side effects of ZERODOL PG 200/75 MG TABLET?

Common side effects include nausea, vomiting, indigestion, stomach pain, diarrhea, heartburn, dry mouth, dizziness, blurred vision, weight gain, sleepiness, tiredness, and uncoordinated body movements. Other possible side effects can include headache, loss of appetite, constipation, flatulence, and mood changes. If these side effects persist or worsen, you should inform your doctor.

Is ZERODOL PG 200/75 MG TABLET safe during pregnancy or breastfeeding?

ZERODOL PG 200/75 MG TABLET is generally not recommended during pregnancy, especially in the last trimester, and may cause moderate side effects. It should be used with caution during breastfeeding, as severe harmful effects have been noted in women who are breastfeeding. It should only be taken if prescribed by a doctor who has carefully weighed the benefits against the potential risks. Women of childbearing potential should use effective contraception while taking this medication.

Can ZERODOL PG 200/75 MG TABLET be taken with other medications?

It is crucial to inform your doctor about all medicines, supplements, or herbal products you are currently taking or plan to take to avoid potential drug interactions. This tablet should not be taken with two or more non-steroidal anti-inflammatory medicines (NSAIDs) as this may increase the risk of side effects. It may interact with quinolone antibiotics (increasing the risk of fits/seizures), antiplatelet medicines (like clopidogrel), and selective serotonin reuptake inhibitors (SSRIs) such as fluoxetine (potentially increasing the risk of stomach/intestinal bleeding). It may also increase the effect of anti-anxiety medicines like lorazepam. Caution is advised when taken with medications for high blood pressure, swelling, heart failure, blood clots, cancer, mental disorders, diabetes, and HIV/AIDS.

What precautions should be taken while using ZERODOL PG 200/75 MG TABLET?

Take this medicine with food to minimize stomach upset. Avoid consuming alcohol, as it can increase drowsiness, dizziness, and the risk of stomach problems. Do not stop taking the medicine suddenly without consulting your doctor, as it can lead to withdrawal symptoms like anxiety, difficulty sleeping, nausea, or headache. As it can cause drowsiness and dizziness, exercise caution while driving or operating machinery until you know how the medicine affects you. Inform your doctor about any pre-existing medical conditions, including heart problems, kidney or liver disease, stomach ulcers, bleeding disorders, diabetes, asthma, bipolar syndrome, or suicidal thoughts. It is not recommended for children under 18 years of age. Pregabalin, a component of this tablet, may decrease sperm count and potentially affect male fertility.

What happens if a dose of ZERODOL PG 200/75 MG TABLET is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one, as this may lead to an overdose.

How should ZERODOL PG 200/75 MG TABLET be stored?

Store ZERODOL PG 200/75 MG TABLET in a cool and dry place, away from direct sunlight and moisture. Keep it out of the sight and reach of children. The recommended storage temperature is below 25°C or 30°C.