Pregeb 75

PREGEB 75 Capsule

PREGEB 75 Capsule is a medication manufactured by Torrent Pharmaceuticals Ltd..

• Name:
  • Brand Name: PREGEB 75 Capsule
  • Common Name: Pregabalin
• Composition: Each capsule contains Pregabalin 75 mg.
• Uses: PREGEB 75 is primarily used as an anticonvulsant and is prescribed for several conditions:
  • Neuropathic Pain: It is effective in treating chronic nerve pain resulting from conditions like diabetic neuropathy, shingles (postherpetic neuralgia), or spinal cord injury.
  • Epilepsy: Used as an adjunctive therapy for adults with partial seizures. It works by reducing abnormal electrical activity in the brain.
  • Fibromyalgia: Helps manage widespread musculoskeletal pain and stiffness associated with fibromyalgia syndrome.
  • Generalized Anxiety Disorder (GAD): In some cases, it may be prescribed for anxiety disorders when other treatments are unsuitable.
• Dosage and Administration:
  • PREGEB 75 Capsule can be taken with or without food, as advised by your doctor.
  • The dosage and duration depend on the medical condition and patient response.
  • It is typically taken in two or three divided doses, with initial doses often starting at 150 mg/day for neuropathic pain, epilepsy, or fibromyalgia, and gradually increasing up to a maximum of 450-600 mg/day.
  • Swallow the capsule whole with water; do not crush, chew, break, or open it.
• Side Effects: Common side effects include:
  • Dizziness
  • Somnolence (sleepiness or drowsiness)
  • Dry mouth
  • Oedema (fluid build-up with swelling)
  • Blurred vision
  • Weight gain
  • Abnormal thinking (difficulty with concentration or attention)
  • Other reported side effects can include headache, fatigue, confusion, nausea, and constipation.
  • Serious side effects, though rare, can include suicidal thoughts or behavior, allergic reactions (swelling of face, lips, difficulty breathing), and heart problems.
• Precautions:
  • Avoid alcohol consumption as it can worsen dizziness and drowsiness.
  • Do not drive or operate heavy machinery until you know how the medicine affects you due to potential dizziness, drowsiness, or blurred vision.
  • Inform your doctor if you have a history of heart disease, kidney problems, diabetes, respiratory disorders, or a history of alcohol or drug addiction.
  • Not recommended during pregnancy or breastfeeding unless specifically advised by a doctor. Use effective contraception if you are a woman of childbearing age.
  • Do not stop taking the medication abruptly, as it can lead to withdrawal symptoms and worsen the condition; dosage should be reduced gradually under medical supervision.
  • Not recommended for children under 18 years of age.
• Storage: Store in a cool and dry place, protected from light and moisture, away from sunlight. Keep it out of the sight and reach of children and pets.

PREGEB 75, manufactured by Torrent Pharmaceuticals Ltd., contains pregabalin as its active ingredient. It is primarily used to manage neuropathic pain, epilepsy, and fibromyalgia, and may also be prescribed for generalized anxiety disorder.

Here are some frequently asked questions about PREGEB 75:

What is PREGEB 75 used for?

PREGEB 75 is used to treat nerve pain (neuropathic pain) caused by conditions such as diabetes, shingles, or spinal cord injury. It is also prescribed for managing fibromyalgia, a condition characterized by widespread muscle pain and stiffness. Additionally, it serves as an adjunctive therapy for certain types of seizures (epilepsy) and may be used for generalized anxiety disorder when other treatments are not suitable.

How does PREGEB 75 work?

The active ingredient, pregabalin, works by calming damaged or overactive nerves in the body. It does this by binding to a specific part of the voltage-dependent calcium channels in the central nervous system, known as the alpha2-delta subunit. This action reduces the release of certain chemical messengers (neurotransmitters) that are involved in transmitting pain signals and nerve activity, thereby alleviating discomfort and stabilizing nerve function.

What is the usual dosage of PREGEB 75?

The dosage of PREGEB 75 (75 mg pregabalin per capsule) varies depending on the condition being treated and individual patient response. For neuropathic pain, treatment may start with 150 mg per day, increasing to a maximum of 600 mg per day in divided doses. For epilepsy, an initial dose of 150 mg per day, given in two or three divided doses, may be increased to a maximum of 600 mg per day. For fibromyalgia, an initial dose of 150 mg per day may be increased to a maximum of 450 mg per day. It is crucial to follow your doctor's prescribed dose and not alter it without medical advice.

What are the possible side effects of PREGEB 75?

Common side effects include dizziness, drowsiness or sleepiness, dry mouth, blurred vision, weight gain, swelling (oedema) in the arms or feet, difficulty concentrating, fatigue, and headache. More serious, though rare, side effects can include allergic reactions like angioedema (swelling of the face, lips, tongue) and, in some cases, unusual changes in mood or behavior, including suicidal thoughts. If any side effects persist or worsen, or if you experience severe symptoms, consult your doctor immediately.

Is PREGEB 75 safe during pregnancy or breastfeeding?

PREGEB 75 is generally not recommended during pregnancy or breastfeeding unless specifically advised by your doctor, as its safety in these situations is not fully established. Animal studies have shown reproductive toxicity, and the potential risk to humans is unknown. Women of childbearing age should use effective contraception while undergoing therapy with this medicine. If you are pregnant, planning to become pregnant, or breastfeeding, discuss the potential risks and benefits with your doctor.

Can PREGEB 75 be taken with other medications?

Caution is advised when taking PREGEB 75 with other medications, particularly those that depress the central nervous system (CNS). Concurrent use with alcohol, benzodiazepines (for anxiety or insomnia), and opioid pain relievers can increase the risk of excessive sedation, drowsiness, dizziness, and respiratory problems. Diabetic patients taking thiazolidinedione antidiabetic agents should be monitored closely, as the combination with pregabalin can increase fluid retention and weight gain. Always inform your doctor about all other medications, supplements, and herbal products you are taking to avoid potential interactions.

What precautions should be taken while taking PREGEB 75?

Avoid consuming alcohol while on PREGEB 75, as it can intensify side effects like dizziness and drowsiness. Do not drive or operate heavy machinery if you experience drowsiness, dizziness, or blurred vision. Inform your doctor if you have a history of kidney, liver, or heart problems, diabetes, or a history of drug or alcohol addiction. Also, report any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts. It is important not to stop taking PREGEB 75 suddenly without consulting your doctor, as this can lead to withdrawal symptoms. This medicine is not recommended for children under 18 years of age.

What happens if a dose of PREGEB 75 is missed?

If you miss a dose of PREGEB 75, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one, as this may increase the risk of side effects. If you are unsure what to do, consult your doctor or pharmacist.

How should PREGEB 75 be stored?

PREGEB 75 should be stored in a cool and dry place, away from direct sunlight and moisture. The ideal storage temperature is typically below 30°C. Keep this medicine out of the sight and reach of children and pets.