Azeldip 16 Mg Tab

AZELDIP 16 MG Tablet

AZELDIP 16 MG Tablet, manufactured by Glenmark Pharmaceuticals Ltd., is a medication prescribed for the management of high blood pressure.

Composition

• Active Ingredient: Azelnidipine 16 mg

Uses AZELDIP 16 Tablet is primarily used to treat hypertension (high blood pressure). It belongs to a class of medicines known as calcium channel blockers, which work by relaxing and widening blood vessels, thereby reducing the workload on the heart and improving blood flow. This action helps in lowering blood pressure and reducing the risk of cardiovascular events such as heart attacks and strokes. It is effective for both stage-I and stage-II hypertension.

Dosage and Administration

• The typical adult dosage is 1/2 to 1 tablet (8 mg to 16 mg of Azelnidipine) once daily.
• It can be taken at any time of the day, with or without food, but it is recommended to take it at the same time each day for consistent levels in the body.
• Swallow the tablet whole with a glass of water; do not chew, crush, or break it.
• The dosage may be adjusted by your doctor based on your blood pressure levels and the severity of your condition.
• Do not stop taking this medicine on your own, even if you feel well, as high blood pressure often has no symptoms and discontinuing it abruptly can worsen your condition.

Side Effects Common Side Effects:

• Headache, dizziness, light-headedness, drowsiness
• Swelling, especially in the ankles or feet
• Itching, rash
• Abdominal pain, nausea, constipation, diarrhea
• Frequent urination
• Fatigue, abnormal sensations
• Sensation of warmth, skin flushing on the face
• Numbness, palpitations

Serious Side Effects (rare):

• Liver problems (e.g., jaundice, nausea, vomiting, loss of appetite)
• Pancreatitis (severe stomach pain)
• Recurrent chest pain, which may indicate a heart attack
• Cardiac arrest (chest pain, irregular heartbeat, shortness of breath), sinus block (heart rhythm disorder), or slowed heart rate (bradycardia) Seek immediate medical attention if you experience any serious side effects.

Precautions

• Inform your doctor if you have any liver, heart, or kidney problems before taking this medicine.
• Pregnant or breastfeeding women should consult their doctor before using AZELDIP 16 Tablet.
• Caution is advised when consuming alcohol with AZELDIP 16 Tablet, as it may increase the risk of low blood pressure and other side effects like dizziness and fainting.
• Avoid consuming grapefruit or grapefruit juice while taking this medicine, as it may increase the risk of low blood pressure and other side effects.
• AZELDIP 16 Tablet may cause dizziness or drowsiness; therefore, avoid driving or operating heavy machinery if you experience these side effects.
• Inform your doctor about all other medicines you are taking, especially those for high blood pressure or heart conditions. Interactions can occur with medicines used for fungal infections (e.g., itraconazole, miconazole), HIV infections (e.g., ritonavir, saquinavir), cimetidine, imatinib, bacterial infections (e.g., erythromycin, clarithromycin, rifampicin), cyclosporine, anxiety/insomnia (e.g., diazepam), seizures (e.g., phenytoin), hormonal contraceptives, digoxin, and simvastatin.

Storage

• Store below 25°C or 30°C.
• Keep in the original packaging, away from direct sunlight, heat, and moisture.
• Keep out of the sight and reach of children.

AZELDIP 16 MG TAB, manufactured by Glenmark Pharmaceuticals Ltd, contains the active ingredient Azelnidipine. This medication is primarily used to treat high blood pressure.

What is AZELDIP 16 MG TAB used for?

AZELDIP 16 MG TAB is primarily used for the treatment of hypertension (high blood pressure). By effectively lowering blood pressure, it helps reduce the risk of serious cardiovascular events such as heart attacks, strokes, and kidney damage.

How does AZELDIP 16 MG TAB work?

AZELDIP 16 MG TAB contains Azelnidipine, which is a calcium channel blocker. It works by inhibiting the influx of calcium ions into the smooth muscle cells of blood vessel walls. This action causes the blood vessels to relax and widen (vasodilation), which reduces the resistance against which the heart pumps blood. As a result, blood pressure decreases, and the heart's workload is reduced.

What is the usual dosage for AZELDIP 16 MG TAB?

For adults, the usual dosage is 8 mg to 16 mg of Azelnidipine once daily, taken after breakfast. The initial dose may be 8 mg, and the doctor may adjust the dosage based on the patient's response and symptoms. The daily maximum dosage should not exceed 16 mg.

What are the possible side effects of AZELDIP 16 MG TAB?

Common side effects may include headaches, dizziness, swelling (particularly in the ankles and feet, known as peripheral edema), weakness, and flushing. Less common but serious side effects can include pancreatitis (severe stomach pain, nausea, and vomiting), liver problems (yellowing of skin, vomiting, nausea, and loss of appetite), and recurrent chest pain, which may be a sign of a heart attack. Most common side effects are usually temporary and resolve over time.

Is AZELDIP 16 MG TAB safe during pregnancy or breastfeeding?

Azelnidipine should be used with caution during pregnancy and breastfeeding. There is limited substantial research on its safety in these populations. It is generally advised not to administer this medication to women who are pregnant or may become pregnant. For breastfeeding mothers, it is desirable to avoid administration; if unavoidable, breastfeeding should be stopped. Always consult your doctor for advice if you are pregnant, planning a pregnancy, or breastfeeding.

Can AZELDIP 16 MG TAB be taken with other medications?

AZELDIP 16 MG TAB can interact with several medications. It's crucial to inform your doctor about all medicines, including over-the-counter drugs, supplements, and herbal remedies, you are currently taking. Particular caution is needed with other antihypertensive agents, as co-administration may lead to excessive hypotension. Azelnidipine is metabolized by the liver enzyme CYP3A4, so drugs that inhibit or induce this enzyme (e.g., certain antifungals, HIV protease inhibitors, anti-epileptics, rifampicin, simvastatin, digoxin) can alter its blood levels.

What precautions should be taken while taking AZELDIP 16 MG TAB?

Patients should avoid consuming grapefruit or grapefruit juice, as it can increase the concentration of Azelnidipine in the blood and lead to severe side effects. Alcohol consumption should be limited, as it may increase the risk of low blood pressure. Due to potential dizziness, caution is advised when driving or operating heavy machinery. Patients with severe liver or kidney dysfunction should use this medicine with caution. It is important not to stop taking AZELDIP 16 MG TAB without your doctor's advice, as sudden discontinuation can cause changes in blood pressure.

What happens if a dose of AZELDIP 16 MG TAB is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

How should AZELDIP 16 MG TAB be stored?

AZELDIP 16 MG TAB should be stored below 25°C. It should be protected from light and moisture and kept out of the reach of children.