Nizer 100 Mg Tablet (10 Tab)

NIZER 100 MG TABLET is a non-steroidal anti-inflammatory drug (NSAID) manufactured by USV PRIVATE LIMITED, primarily used for its pain-relieving, anti-inflammatory, and fever-reducing properties.

Name

• Brand Name: NIZER 100 MG TABLET
• Common Name: Nimesulide (active ingredient)

Composition Each tablet contains Nimesulide 100 mg.

Uses NIZER 100 MG TABLET is prescribed for a variety of inflammatory and painful conditions, including:

• Acute pain
• Headache
• Muscle pain and joint pain (such as rheumatoid arthritis, osteoarthritis)
• Dental pain
• Back pain
• Menstrual pain (dysmenorrhea)
• Post-traumatic and post-operative painful conditions
• Fever

Dosage and Administration Take NIZER 100 MG TABLET as advised by your physician, usually 1-2 times daily. It should be swallowed whole with a glass of water, preferably after meals, to minimize gastrointestinal discomfort. Do not crush or chew the tablet. The duration of treatment should be for the stipulated period prescribed by your doctor, as long-term use is not recommended.

Side Effects Common side effects may include:

• Nausea, vomiting, diarrhea, stomach upset, abdominal discomfort
• Dizziness, excess sleepiness
• Elevated liver enzymes

Serious side effects, though less common, can include gastrointestinal bleeding, ulcers, liver damage (hepatotoxicity), and allergic reactions. Consult your doctor if any side effects persist or worsen.

Precautions

• Contraindications: Do not take NIZER 100 MG TABLET if you are allergic to Nimesulide or other NSAIDs, or if you have severe kidney, liver, or heart disease. It is also not recommended for those with active stomach or duodenal ulcers, gastrointestinal bleeding, or bleeding disorders.
• Pregnancy and Breastfeeding: Not recommended during the third trimester of pregnancy and in breastfeeding women.
• Children: Not recommended for use in children under 12 or 18 years of age.
• Alcohol: Avoid alcohol consumption during treatment.
• Drug Interactions: Inform your doctor about all medications you are taking, as NIZER can interact with anticoagulants, corticosteroids, diuretics, and ACE inhibitors.
• Monitoring: Regular liver function tests may be advised during treatment.

Storage Store NIZER 100 MG TABLET in a cool and dry place, away from direct sunlight, moisture, and heat. Keep it in its original packaging and out of the sight and reach of children. Store below 25°C or 30°C.

What is NIZER 100 MG Tablet used for?

NIZER 100 MG Tablet, containing Nimesulide, is a non-steroidal anti-inflammatory drug (NSAID) primarily used for pain relief, fever reduction, and managing inflammatory conditions. It provides relief from mild to moderate pain such as headaches, toothaches, joint pain, muscle pain, backache, and menstrual cramps (dysmenorrhea). It is also used for post-operative pain and pain associated with osteoarthritis and rheumatoid arthritis.

How does NIZER 100 MG Tablet work?

NIZER 100 MG Tablet works by blocking the production of certain chemical messengers in the body called prostaglandins. Prostaglandins are responsible for causing pain, inflammation (redness and swelling), and fever. By inhibiting cyclooxygenase (COX) enzymes, particularly COX-2, Nimesulide reduces these effects, thereby alleviating pain and inflammation.

What is the usual dosage for NIZER 100 MG Tablet?

For adults, the usual dosage is 100 mg twice a day. It should be taken with food to help prevent stomach upset. It is recommended to use the lowest effective dose for the shortest possible duration to control symptoms, and the maximum duration of a treatment course should not exceed 15 days. NIZER 100 MG Tablet is not recommended for children below 12 or 18 years of age.

What are the possible side effects of NIZER 100 MG Tablet?

Common side effects may include nausea, vomiting, diarrhea, stomach pain or cramps, indigestion, dizziness, and elevated liver enzymes. More serious, but rare, side effects can occur, such as liver damage (hepatotoxicity, which can be severe), gastrointestinal bleeding or ulceration, skin rash, allergic reactions (like swelling or difficulty breathing), blood clotting problems, and kidney issues.

Is NIZER 100 MG Tablet safe during pregnancy or breastfeeding?

No, NIZER 100 MG Tablet is not recommended during pregnancy, especially in the third trimester, as it may harm the unborn baby and has been linked to kidney failure in newborns. It is contraindicated during pregnancy. For breastfeeding mothers, the use of NIZER 100 MG Tablet is also not recommended as it is unknown if Nimesulide passes into breast milk, and it may be unsafe for the baby.

Can NIZER 100 MG Tablet be taken with other medications?

NIZER 100 MG Tablet can interact with several medications. It may interact with blood thinners (like warfarin and aspirin), antidiabetics (like insulin), anti-epileptics (like phenytoin), anti-cancer agents (like methotrexate), immune system affecting medicines (like cyclosporine), diuretics, and antacids. Simultaneous use of different NSAIDs, including paracetamol, is generally not recommended due to an increased risk of side effects. Always inform your doctor about all medications you are currently taking to avoid potential interactions.

What precautions should be taken while using NIZER 100 MG Tablet?

Before taking NIZER 100 MG Tablet, inform your doctor if you have any allergies to Nimesulide or other medications, or if you have a history of liver disease (it's contraindicated in severe hepatic impairment), kidney disease (use with caution), heart disease (use with caution, contraindicated in severe heart failure), active stomach ulcers, gastrointestinal bleeding, asthma, or bleeding disorders. Avoid alcohol consumption and dairy products (milk, yogurt, calcium-fortified juices) while taking this medicine. Do not use it for prolonged periods, as the maximum recommended duration is 15 days due to the risk of severe liver damage, stomach ulcers, or kidney problems. If you experience dizziness or eyesight problems, avoid driving or operating machinery.

What happens if a dose of NIZER 100 MG Tablet is missed?

If you miss a dose of NIZER 100 MG Tablet, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to compensate for the missed one.

How should NIZER 100 MG Tablet be stored?

NIZER 100 MG Tablet should be stored at room temperature, typically between 20°C and 25°C (68°F and 77°F), or below 30°C. Keep it in a cool, dry place, protected from direct light and moisture, and in its original packaging. Ensure that the medication is kept out of sight and reach of children and pets.

Is NIZER 100 MG Tablet safe for children?

NIZER 100 MG Tablet is generally not recommended for use in children below 12 years of age, and some sources specify not for use below 18 years, as its safety and efficacy have not been established in these age groups.