ZERODOL TH MAX 4 Tablet

Name

Brand Name: Zerodol TH Max 4 Common Name: Aceclofenac, Paracetamol, and Thiocolchicoside combination tablet.

Composition

Each tablet typically contains a combination of three active ingredients:

• Aceclofenac: 100 mg (a non-steroidal anti-inflammatory drug - NSAID)
• Paracetamol (Acetaminophen): 325 mg (an analgesic)
• Thiocolchicoside: 4 mg (a muscle relaxant)

Uses

Zerodol TH Max 4 Tablet is a combination medicine primarily used to relieve pain, inflammation, and muscle spasms associated with various musculoskeletal and joint disorders. It is prescribed for adults for conditions such as:

• Osteoarthritis
• Rheumatoid arthritis
• Ankylosing spondylitis
• Muscle pain, including lower back pain, neck and shoulder pain
• Bone and joint pain
• Sciatica (nerve pain)
• Degenerative vertebral disorders
• Painful muscle contractions, strains, and sprains
• Headache, toothache, colds, influenza, and menstrual cramps (off-label uses)

Dosage and Administration

• Typical Guidance: Take Zerodol TH Max 4 Tablet as directed by your physician.
• Method: Swallow the tablet whole with a glass of water. Do not crush, chew, or break it.
• Timing: It is advised to take this medicine with food to avoid stomach upset.
• Duration: The dose and duration of treatment will depend on the severity of your condition and should be followed as prescribed by your doctor.

Side Effects

Common side effects may include:

• Nausea
• Vomiting
• Stomach pain / Abdominal pain
• Loss of appetite
• Heartburn
• Diarrhea
• Dizziness
• Drowsiness

Serious side effects that require immediate medical attention (though less common) include:

• Increased liver enzyme levels
• Bleeding in the stomach or intestine
• Allergic reactions like skin rashes

Precautions

• Allergies: Do not take if you are allergic to aceclofenac, paracetamol, thiocolchicoside, or any other NSAIDs.
• Pregnancy and Breastfeeding: Not recommended for use during pregnancy as it may cause abnormalities in the unborn baby. Avoid while breastfeeding as components may pass into breastmilk. Consult your doctor.
• Alcohol Consumption: Avoid alcohol as it can increase drowsiness and the risk of stomach bleeding and liver damage.
• Pre-existing Conditions: Inform your doctor if you have:
  • Severe liver or kidney diseases
  • Stomach ulcers, intestinal bleeding, or a history of such conditions
  • Heart problems, high blood pressure, or a history of heart attack/stroke
  • Bleeding disorders
  • Asthma or other respiratory disorders
  • Diabetes
• Driving and Machinery: May cause dizziness and drowsiness; exercise caution when driving or operating machinery.
• Children: Not recommended for children below 16 or 18 years of age as safety and efficacy have not been established.
• Elderly Patients: Use with caution in elderly patients (>65 years) as they may be more prone to side effects like drowsiness, confusion, and a higher risk of falls.
• Drug Interactions: Inform your doctor about all other medications (prescription, over-the-counter, herbal) you are taking, especially other NSAIDs, anticoagulants, antihypertensives, diuretics, antidiabetic medicines, or medicines for nausea/vomiting.

Storage

• Store below 30°C.
• Protect from light and moisture.
• Keep out of reach and sight of children.

What is Zerodol TH Max 4 used for?

Zerodol TH Max 4 is a combination medicine primarily used to relieve pain and inflammation associated with various musculoskeletal and joint conditions. These include osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, muscle pain, bone and joint pain, lower back pain, neck and shoulder pain, sciatica, degenerative vertebral disorders, muscle spasms, headaches, menstrual cramps, and toothaches.

How does Zerodol TH Max 4 work?

Zerodol TH Max 4 contains three active ingredients: Thiocolchicoside, Aceclofenac, and Paracetamol. Thiocolchicoside acts as a muscle relaxant, working on the central nervous system (spinal cord and brain) to relieve muscle stiffness and improve muscle movement. Aceclofenac, a non-steroidal anti-inflammatory drug (NSAID), and Paracetamol, an analgesic, work by blocking the production of chemical messengers called prostaglandins that are responsible for causing pain and inflammation.

What is the usual dosage for Zerodol TH Max 4?

The exact dosage and duration of Zerodol TH Max 4 should be determined by your doctor based on your medical condition. It is typically advised to swallow the tablet whole with a glass of water, preferably with food, to minimize stomach upset. Do not crush, chew, or break the tablet. For conditions like osteoarthritis, a common recommendation is one tablet twice daily after meals.

What are the possible side effects of Zerodol TH Max 4?

Common side effects may include nausea, vomiting, stomach pain, loss of appetite, heartburn, diarrhea, dizziness, drowsiness, and increased liver enzymes. If these side effects persist or worsen, it is advisable to consult your doctor. More serious side effects can include stomach bleeding and allergic reactions, requiring immediate medical attention.

Is Zerodol TH Max 4 safe during pregnancy or breastfeeding?

Zerodol TH Max 4 is generally not recommended during pregnancy, especially in the last trimester, due to potential risks of abnormalities in the unborn baby. It is also contraindicated during breastfeeding because its components may pass into breast milk and could have adverse effects on the infant. Always consult your doctor if you are pregnant, planning a pregnancy, or breastfeeding before taking this medicine.

Can Zerodol TH Max 4 be taken with other medications?

Zerodol TH Max 4 can interact with several other medications. It is crucial to inform your doctor about all medicines you are currently taking, including over-the-counter drugs, herbal supplements, and vitamins, to avoid potential interactions. Avoid taking it concurrently with other NSAIDs or medicines containing acetaminophen, as this can increase the risk of side effects. It may interact with medications for nausea or vomiting (e.g., metoclopramide, ondansetron), antihypertensive medicines (e.g., amlodipine, enalapril), antidepressants (e.g., lithium, fluoxetine, sertraline), gout medications (e.g., allopurinol, colchicine, probenecid), heart conditions (e.g., digoxin), anti-HIV medicines (e.g., zidovudine), and certain diuretics (e.g., furosemide).

What precautions should be taken while using Zerodol TH Max 4?

Several precautions should be observed:

• Alcohol: Avoid consuming alcohol as it can increase drowsiness and significantly raise the risk of stomach bleeding and liver damage.
• Driving/Operating Machinery: This medicine can cause dizziness, drowsiness, or visual disturbances. Therefore, avoid driving or operating heavy machinery until you know how the medication affects you.
• Pre-existing Conditions: Inform your doctor if you have severe liver or kidney disease, heart problems (like heart failure, high blood pressure), a history of stomach ulcers or gastrointestinal bleeding, asthma, inflammatory bowel disease, diabetes, high cholesterol, or bleeding disorders.
• Children: Zerodol TH Max 4 is generally not recommended for use in children below 18 years of age as its safety and efficacy have not been established.
• Dosage: Do not exceed the prescribed dose or duration of treatment without consulting your doctor, as this can increase the risk of side effects and liver damage.

What happens if a dose of Zerodol TH Max 4 is missed?

If you miss a dose of Zerodol TH Max 4, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

How should Zerodol TH Max 4 be stored?

Zerodol TH Max 4 tablets should be stored below 25°C in a cool, dry place. Protect the medicine from light and moisture to maintain its effectiveness. Always keep the product out of reach and sight of children to prevent accidental ingestion.