Syscan 200

SYSCAN 200

SYSCAN 200 is an antifungal medication manufactured by Torrent Pharmaceuticals Ltd.

• Name:

  • Brand Name: SYSCAN 200
  • Common Name: Fluconazole

• Composition:

  • Each SYSCAN 200 capsule contains Fluconazole 200 mg as the active ingredient.

• Uses: SYSCAN 200 is primarily used to treat various fungal infections caused by Candida and Cryptococcus species.

  • Candidiasis: Includes oropharyngeal (mouth and throat), vaginal (vulvovaginal), esophageal, systemic (affecting blood, brain, heart, eyes), hepatosplenic, and non-life-threatening infections like cystitis. It is effective for oral or vaginal candidiasis unresponsive to nystatin or clotrimazole.
  • Cryptococcal Infections: Such as cryptococcal meningitis (affecting the brain and spinal cord) and secondary prophylaxis for cryptococcal meningitis in persons with AIDS.
  • Dermatological Fungal Infections: Including ringworm, athlete's foot, jock itch, and nail infections.
  • Prophylactic Use: Prescribed as a preventive measure against fungal infections in immunocompromised patients, such as those with HIV, undergoing chemotherapy, radiation therapy, or bone marrow transplantation.

• Dosage and Administration:

  • SYSCAN 200 is for oral administration.
  • It can be taken with or without food.
  • The dosage and duration depend on the condition being treated and the patient's response, as determined by a doctor.
  • It is crucial to complete the full prescribed course of treatment, even if symptoms improve, to ensure complete eradication of the infection and prevent recurrence or development of resistant strains.
  • If a dose is missed, take it as soon as possible. However, if it is almost time for the next dose, skip the missed dose.

• Side Effects:

  • Common Side Effects: Nausea, vomiting, abdominal pain, diarrhea, headache, dizziness, rash, altered food tastes, and elevated liver enzymes.
  • Serious Side Effects: Liver damage (indicated by yellowing of skin/eyes, dark urine, severe stomach pain), severe skin rash (e.g., blistering), and allergic reactions (swelling of lips, throat, face; difficulty swallowing or breathing). Rarely, hair loss and fits may occur.

• Precautions:

  • Pregnancy and Breastfeeding: Not recommended during pregnancy due to potential risks to the fetus unless clearly necessary and advised by a doctor. Women of childbearing potential should use reliable contraception during and for at least one week after treatment. Use with caution in breastfeeding mothers, especially after repeated or high doses.
  • Medical Conditions: Inform your doctor if you have liver, kidney, or heart problems, or abnormal levels of potassium, calcium, or magnesium in your blood. Regular monitoring of liver function may be advised, especially for prolonged use.
  • Drug Interactions: May interact with oral contraceptives, coumarin-type anticoagulants (e.g., warfarin), antiepileptics (e.g., phenytoin), immunosuppressants (e.g., cyclosporine), and some antibiotics (e.g., rifampin).
  • Antacids: Avoid taking antacids within one hour before or two hours after taking SYSCAN 200.
  • Alcohol: Caution is advised when consuming alcohol.
  • Driving/Operating Machinery: May cause dizziness or fits, so refrain from driving or operating heavy machinery if affected.

• Storage:

  • Store in a cool and dry place, away from sunlight and moisture.
  • Keep below 25°C or 30°C.
  • Keep out of reach of children.

Syscan 200 by Torrent Pharmaceuticals Ltd. is an antifungal medication containing Fluconazole. It is used to treat various fungal infections throughout the body.

What is SYSCAN 200 used for?

SYSCAN 200 is primarily used to treat a wide range of fungal infections caused by Candida and Cryptococcus species. This includes systemic candidiasis (infections affecting the blood, brain, heart, or eyes), mucosal candidiasis (infections of the mouth, throat, or denture sore mouth), cryptococcosis (especially affecting the lungs and brain), vaginal candidiasis, vulvovaginal candidiasis, and dermatological fungal infections like athlete's foot, ringworm, and nail infections. It can also be prescribed as a preventive measure for fungal infections in immunocompromised patients, such as those with HIV or undergoing chemotherapy, radiotherapy, or bone marrow transplantation.

How does SYSCAN 200 work?

SYSCAN 200 contains Fluconazole, which acts by inhibiting a specific fungal enzyme called cytochrome P450 enzyme 14α-demethylase. This enzyme is crucial for the synthesis of ergosterol, a vital component of the fungal cell membrane. By blocking its production, Fluconazole disrupts the integrity of the fungal cell membrane, leading to leakage of cellular contents and ultimately inhibiting fungal growth or killing the fungus.

What is the usual dosage for SYSCAN 200?

The dosage of SYSCAN 200 is determined by your doctor based on the type and severity of the infection, and your response to the treatment. It should be taken exactly as prescribed, typically at evenly spaced times. Do not increase or exceed the prescribed dosage without consulting your doctor.

What are the possible side effects of SYSCAN 200?

Common side effects include nausea, vomiting, abdominal pain, diarrhea, headache, dizziness, rash, stomach upset, and elevated liver enzymes. If these symptoms persist or worsen, you should consult your doctor. More serious but rare side effects can include severe skin reactions (like blistering), allergic reactions (rash, swelling of the face/lips/throat, difficulty breathing/swallowing), and liver damage (which may manifest as jaundice or dark urine). Seek immediate medical attention if you experience signs of an allergic reaction or severe adverse effects.

Is SYSCAN 200 safe during pregnancy or breastfeeding?

SYSCAN 200 is generally considered unsafe during pregnancy, especially at high doses, due to potential risks to the developing fetus and an increased risk of miscarriage. It should only be used if the potential benefits clearly outweigh the risks, and under strict medical guidance. Women of childbearing potential are advised to use reliable contraception during treatment and for at least one week after stopping the medicine.

Regarding breastfeeding, SYSCAN 200 does pass into breast milk. While a single dose might be acceptable, repeated or high doses are usually not recommended. Always consult your doctor before using this medication if you are breastfeeding.

Can SYSCAN 200 be taken with other medications?

SYSCAN 200 can interact with several other medications, which may alter their effects or increase the risk of side effects. Some medications, such as terfenadine, cisapride, astemizole, quinidine, and erythromycin, are generally contraindicated with Fluconazole due to a risk of serious heart rhythm problems. Other medications that require caution or dose adjustment include oral contraceptives, certain diabetes medications (sulfonylureas), blood thinners (like warfarin), anti-epileptic drugs (like phenytoin), and immunosuppressants (like cyclosporine). It is crucial to inform your doctor about all prescription, over-the-counter, herbal, and vitamin supplements you are currently taking to avoid potential drug interactions.

What precautions should be taken while using SYSCAN 200?

Before starting SYSCAN 200, inform your doctor if you have a history of liver, kidney, or heart problems, abnormal electrolyte levels, diabetes, a weakened immune system, or cancer. Your doctor may monitor your liver function, especially during prolonged treatment. Avoid or limit alcohol consumption while on this medication. If you experience dizziness, refrain from driving or operating machinery. Also, avoid taking antacids within one hour before or two hours after taking SYSCAN 200. It is important to complete the full course of treatment, even if your symptoms improve, to ensure the infection is fully cured and to prevent recurrence.

What happens if a dose of SYSCAN 200 is missed?

If you miss a dose of SYSCAN 200, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one, as this can increase the risk of side effects.

How should SYSCAN 200 be stored?

SYSCAN 200 should be stored in a cool and dry place, away from direct sunlight and moisture. Keep the medication out of the reach and sight of children. Typically, it should be stored at temperatures below 25°C or 30°C.