Vonalong 10mg Tab

VONALONG 10MG TABLET

VONALONG 10MG TABLET is a medication manufactured by Mankind Pharma Ltd. primarily used to manage conditions related to excess stomach acid.

Composition Each tablet contains Vonoprazan 10mg as its active ingredient. Vonoprazan is a novel potassium-competitive acid blocker (P-CAB) that works by inhibiting the H+/K+-ATPase enzyme in the stomach's parietal cells, thereby reducing gastric acid secretion. This mechanism provides faster and more sustained acid suppression compared to traditional proton pump inhibitors (PPIs).

Uses VONALONG 10MG TABLET is prescribed for:

• Treatment and prevention of gastric and duodenal ulcers (sores in the stomach or intestine lining).
• Healing damage to the esophagus caused by excess stomach acid (reflux esophagitis) and alleviating associated heartburn and acid reflux symptoms.
• Preventing the recurrence of gastric or duodenal ulcers, especially during the use of low-dose aspirin or NSAIDs.
• Aiding in the eradication of Helicobacter pylori bacteria, in combination with other antibiotics, to prevent stomach ulcers.

Dosage and Administration VONALONG 10MG TABLET should be swallowed whole with plenty of water and not chewed or crushed. It can be taken with or without food. The dosage is typically once or twice daily, or as directed by a healthcare professional. Patients should avoid lying down immediately after taking the medication to prevent acid reflux.

Side Effects Common side effects may include:

• Diarrhea
• Stomach pain
• Nausea
• Indigestion
• Bloating
• High blood pressure
• Urinary tract infection

More serious, though less common, side effects can include kidney problems, Clostridioides difficile-associated diarrhea, bone fractures, severe skin reactions, low vitamin B12 levels, low magnesium levels, or fundic gland polyps.

Precautions Inform your doctor if you have known allergies to Vonoprazan or other ingredients. Use with caution in patients with kidney or liver disease. Pregnant or breastfeeding women should consult their doctor before use. It is advisable to avoid alcohol, spicy, acidic, fatty foods, caffeine, and smoking, as these can exacerbate symptoms. VONALONG 10MG TABLET can interact with other medications, such as Rilpivirine (used for HIV/AIDS), reducing its effectiveness. It may also reduce the effect of medicines that require an acidic stomach environment to work effectively. Inform your doctor about all current medications, supplements, and pre-existing conditions, including low magnesium, calcium, or potassium levels.

Storage Store VONALONG 10MG TABLET in a cool and dry place, below 30°C, away from direct sunlight. Keep out of the sight and reach of children.

VONALONG 10MG Tablet by Mankind Pharma Ltd.

What is VONALONG 10MG Tablet used for?

VONALONG 10MG Tablet, containing Vonoprazan, is primarily used to treat conditions associated with excessive stomach acid. These conditions include acid reflux (gastroesophageal reflux disease or GERD), stomach ulcers, duodenal ulcers, and it can also be used in combination with antibiotics to treat Helicobacter pylori infection. It helps heal damage to the esophagus caused by stomach acid and prevents the recurrence of ulcers.

How does VONALONG 10MG Tablet work?

VONALONG 10MG Tablet works as a potassium-competitive acid blocker (P-CAB). Its active ingredient, Vonoprazan, inhibits the H+, K+-ATPase enzyme in the parietal cells of the stomach lining. This action effectively reduces the amount of acid produced in the stomach, thereby providing relief from acid-related discomfort and allowing ulcers to heal. Unlike some other acid blockers, Vonoprazan does not require acid activation and can bind to the pumps regardless of their activity.

What is the usual dosage for VONALONG 10MG Tablet?

The typical starting dose for adults for Vonoprazan is often 20 mg once daily, but VONALONG is available in 10mg strength. You should always take VONALONG 10MG Tablet exactly as prescribed by your doctor. It can be taken with or without food.

What are the possible side effects of VONALONG 10MG Tablet?

Common side effects associated with VONALONG 10MG Tablet may include nausea, diarrhea, indigestion, bloating, and stomach pain. Other reported side effects include high blood pressure and urinary tract infection. If these effects persist or worsen, it is advisable to consult your doctor.

Is VONALONG 10MG Tablet safe during pregnancy or breastfeeding?

The safety of VONALONG 10MG Tablet (Vonoprazan) during pregnancy and breastfeeding has not been well established. It is crucial to consult your doctor if you are pregnant, planning to become pregnant, or breastfeeding to discuss the potential risks and benefits before taking this medication.

Can VONALONG 10MG Tablet be taken with other medications?

VONALONG 10MG Tablet can interact with certain other medications. It may reduce the effectiveness of some HIV/AIDS medications like Rilpivirine, Nelfinavir, and Atazanavir. Additionally, it can reduce the absorption and effectiveness of medicines that require an acidic environment in the stomach to work properly, such as iron salts, Erlotinib, Dasatinib, Nilotinib, Mycophenolate mofetil, and Ketoconazole/Itraconazole. Always inform your doctor about all other medications, supplements, and herbal products you are currently taking to avoid potential interactions.

What precautions should be taken while using VONALONG 10MG Tablet?

Do not take VONALONG 10MG Tablet if you have a known allergy to Vonoprazan. Use this medication with caution if you have severe liver problems. While taking this tablet, it is advisable to avoid foods and drinks that can trigger acid production, such as spicy foods, alcohol, and caffeine. Smoking should also be avoided as it can worsen GERD symptoms.

What happens if a dose of VONALONG 10MG Tablet is missed?

If you miss a dose of VONALONG 10MG Tablet, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

How should VONALONG 10MG Tablet be stored?

VONALONG 10MG Tablet should be stored in a cool and dry place, away from direct sunlight and moisture. It is important to keep the medication out of the sight and reach of children.