Pregadoc 75

PREGADOC 75 by LUPIN LTD

Name

• Brand Name: PREGADOC 75 Capsule
• Common Name: Pregabalin (active ingredient)

Composition

• Active Ingredient: Pregabalin (75 mg)

Uses

PREGADOC 75 Capsule is an anticonvulsant primarily used for the management of various conditions involving nerve pain and seizures. It works by calming damaged or overactive nerves in the body.

• Neuropathic Pain: Treatment of pain caused by nerve damage due to conditions such as diabetic neuropathy, postherpetic neuralgia (shingles), and spinal cord injury.
• Epilepsy: Used as an adjunctive therapy for adult patients with partial-onset seizures.
• Fibromyalgia: Management of widespread musculoskeletal pain and stiffness.
• Generalized Anxiety Disorder (GAD): May be prescribed to treat anxiety symptoms when other medicines are not suitable.

Dosage and Administration

PREGADOC 75 Capsule should be taken as directed by a healthcare professional. It can be taken with or without food.

• Typical Guidance: The usual dose often starts at 75 mg, typically taken twice daily, but the doctor may adjust the dosage based on the patient's condition and response.
• Important Note: Do not stop taking this medication suddenly, as it can worsen symptoms or lead to withdrawal effects. The dose should be gradually decreased under medical supervision.

Side Effects

Most side effects are generally mild and may resolve on their own, but severe reactions require immediate medical attention.

• Common Side Effects: Dizziness, somnolence (sleepiness/drowsiness), dry mouth, oedema (fluid build-up with swelling), blurred vision, weight gain, abnormal thinking (difficulty with concentration or attention), fatigue, headache, constipation, increased appetite, tingling or numbness, muscle cramps, joint or back pain.
• Serious Side Effects (Rare): Severe allergic reactions (rash, itching, difficulty breathing, swelling), muscle pain/tenderness/weakness, thoughts of self-harm or suicidal behavior, vision problems (blurred or double vision).

Precautions

• Kidney Impairment: Use with caution in patients with kidney disease; dosage adjustments may be necessary.
• Alcohol Consumption: Avoid alcohol as it can increase drowsiness and dizziness.
• Driving and Operating Machinery: This medicine can cause dizziness, sleepiness, or blurred vision. Patients should avoid driving or operating heavy machinery until they understand how the medication affects them.
• Pregnancy and Breastfeeding: Consult a doctor if pregnant or breastfeeding, as the medicine may be unsafe during these periods.
• Abrupt Discontinuation: Do not stop the medication suddenly due to the risk of withdrawal symptoms or worsening of the underlying condition.
• Addiction Potential: Pregabalin has the potential for habit formation, especially with prolonged use or at higher doses.
• Other Conditions: Caution is advised for patients with heart problems, diabetes, respiratory disorders, or those above 60 years of age (increased risk of falls).
• Pediatric Use: Not recommended for patients below 18 years of age.

Storage

• Store below 30°C, protected from light and moisture.
• Keep out of the reach of children and pets.

PREGADOC 75, manufactured by LUPIN LTD, is a medication primarily containing Pregabalin. It is commonly prescribed for various conditions related to nerve function and pain.

What is PREGADOC 75 used for?

PREGADOC 75 is primarily used to treat neuropathic pain (nerve pain) caused by conditions such as diabetic neuropathy, shingles (postherpetic neuralgia), and spinal cord injury. It is also used to manage fibromyalgia (widespread musculoskeletal pain) and as an adjunctive therapy for partial-onset seizures in adults (a type of epilepsy). Additionally, it may be used to treat generalized anxiety disorder.

How does PREGADOC 75 work?

The active ingredient, Pregabalin, works by calming damaged or overactive nerves in the body. It binds to calcium channels in the brain and spinal cord, which helps reduce the release of certain neurotransmitters involved in pain and anxiety, thereby decreasing the number of pain signals transmitted by damaged nerves.

What is the usual dosage for PREGADOC 75?

The typical dosage for adults often starts at 75 mg and may be adjusted by your doctor based on your condition and response to the medication. It can usually be taken with or without food. For optimal effectiveness, it is recommended to take the capsule at the same time each day. You should take PREGADOC 75 for as long as your doctor has prescribed it.

What are the possible side effects of PREGADOC 75?

Common side effects may include dizziness, sleepiness (somnolence), dry mouth, blurred vision, weight gain, and oedema (fluid build-up with swelling). Other reported side effects include headache, fatigue, nausea, and difficulty concentrating. Most side effects are generally mild and may resolve on their own, but if they persist or worsen, you should consult your doctor.

Is PREGADOC 75 safe during pregnancy or breastfeeding?

PREGADOC 75 is generally not recommended during pregnancy or breastfeeding unless specifically advised by a doctor. It is classified as a Pregnancy Category C drug, meaning that animal studies have shown an adverse effect on the fetus. Pregabalin, the active ingredient, passes into breast milk, but its effect on a breastfed baby is unknown. Women of childbearing age taking this medicine should use effective contraception.

Can PREGADOC 75 be taken with other medications?

It is crucial to inform your doctor about all other medications, supplements, or herbal preparations you are currently taking, as PREGADOC 75 can interact with certain drugs. Interactions can occur with medicines for brain-related disorders or those that cause sleepiness or dizziness, such as certain pain medications (e.g., oxycodone) and some drugs for anxiety or sleep disorders (e.g., Lorazepam). Combining it with alcohol can also worsen side effects like dizziness and drowsiness.

What precautions should be taken while using PREGADOC 75?

Caution should be exercised if you have kidney disease, as dosage adjustments may be necessary. Avoid alcohol consumption as it can increase drowsiness and dizziness. This medication may cause dizziness and sleepiness, so avoid driving or operating heavy machinery until you understand how it affects you. Inform your doctor if you have a history of suicidal thoughts, mood disorders, or heart problems. Do not stop taking the medicine abruptly, as this can lead to withdrawal symptoms. It is not recommended for individuals under 18 years of age.

What happens if a dose of PREGADOC 75 is missed?

If you miss a dose of PREGADOC 75, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

How should PREGADOC 75 be stored?

PREGADOC 75 should be stored in a cool and dry place, away from direct sunlight. Keep it out of the sight and reach of children. The storage temperature should ideally be between 10ºC to 25ºC or below 30ºC.