Lacoset 150 Mg Tablet (10 Tab)

LACOSET 150 MG TABLET

LACOSET 150 MG TABLET is an antiepileptic medication manufactured by Sun Pharmaceutical Industries Ltd.

Composition

LACOSET 150 MG TABLET contains Lacosamide (150 mg) as its active ingredient.

Uses

LACOSET 150 MG TABLET is primarily used to control and prevent epilepsy and seizures. It is effective in managing focal (partial) onset seizures in adults and children aged four years and older. It can be prescribed as a standalone therapy (monotherapy) or as an add-on therapy in combination with other antiepileptic drugs, especially when current medications are insufficient to control seizures. The medication works by decreasing abnormal and excessive electrical activity of nerve cells in the brain.

Dosage and Administration

LACOSET 150 MG TABLET should be taken as advised by a doctor, preferably at the same time each day, with or without food. The tablet should be swallowed whole and not crushed, chewed, or broken. The dosage depends on factors such as age, body weight, and the specific medical condition being treated. It is crucial to complete the full course of treatment even if symptoms improve and not to stop the medication abruptly without consulting a doctor, as this can lead to a recurrence or increase in seizure frequency. If a dose is missed, it should be taken as soon as remembered, unless it's almost time for the next dose.

Side Effects

Common side effects of LACOSET 150 MG TABLET may include:

• Headache
• Dizziness
• Nausea
• Vomiting
• Double vision (diplopia) or blurred vision
• Fatigue or sleepiness
• Dry mouth
• Muscle spasms or tremors
• Confusion
• Trouble walking or difficulties in coordinating movements

Serious side effects, though rare, can include:

• Suicidal thoughts or behavior
• Abnormal heartbeat (e.g., rapid, irregular, or slow heartbeat, palpitations, shortness of breath, feeling lightheaded, fainting)
• Allergic reactions (rash, itching, swelling, severe dizziness, difficulty breathing)
• Mood disturbances (anxiety, irritability, aggression, depression)

Most common side effects are usually temporary and may diminish over time. However, if any side effects persist, worsen, or if serious side effects occur, medical attention should be sought immediately.

Precautions

• Heart Problems: Inform your doctor if you have a history of heart-related problems, especially certain heartbeat issues like second or third-degree AV block, atrial fibrillation, atrial flutter, heart failure, or a history of heart attack, as Lacoset can affect heart rhythm.
• Pregnancy and Breastfeeding: LACOSET 150 MG TABLET is generally not recommended for use during pregnancy or breastfeeding, and a doctor should be consulted regarding potential risks and benefits.
• Liver and Kidney Disease: Use with caution in patients with severe liver or kidney disease, as it may lead to increased side effects or altered effectiveness.
• Alcohol: Avoid or limit alcohol consumption while taking this medication, as it may increase side effects such as dizziness and drowsiness.
• Driving and Operating Machinery: This medicine can cause dizziness, drowsiness, blurred vision, or problems with coordination. Patients should avoid driving or operating heavy machinery until they understand how the medicine affects them.
• Allergies: Do not take Lacoset 150 Tablet if you are allergic to lacosamide or any of its components.
• Drug Interactions: Inform your doctor about all medicines, supplements, or herbal remedies you are currently taking to avoid potential drug-drug interactions, especially with medications that affect heart rhythm (e.g., carbamazepine, lamotrigine, pregabalin) or certain antifungals (fluconazole, itraconazole, ketoconazole), HIV medicine (ritonavir), or antibiotics (clarithromycin, rifampicin).
• Weight Gain: Monitor weight during treatment, as this medication may lead to weight gain. A healthy diet and regular exercise can help manage this side effect.

Storage

LACOSET 150 MG TABLET should be stored in a cool and dry place, away from direct sunlight, and out of sight and reach of children and pets. It should be stored below 30°C or between 10ºC to 25ºC.

What is LACOSET 150 MG TABLET used for?

LACOSET 150 MG TABLET, containing lacosamide, is an antiepileptic medication primarily used to manage and prevent seizures in adults and children aged 4 years and older. It is used for partial-onset seizures and can also be used as an add-on therapy for primary generalized tonic-clonic seizures. It can be prescribed as a standalone therapy or in combination with other anti-epileptic drugs.

How does LACOSET 150 MG TABLET work?

Lacoset 150 MG Tablet works by stabilizing the electrical activity of nerve cells in the brain. Its precise mechanism of action involves selectively enhancing the slow inactivation of voltage-gated sodium channels, which helps to decrease abnormal and excessive neuronal firing that leads to seizures.

What is the usual dosage of LACOSET 150 MG TABLET?

The dosage of LACOSET 150 MG TABLET varies based on the patient's age, body weight, and response to treatment, and should always be determined by a doctor. For adults, the usual starting dose is often 50 mg twice daily, which may be gradually increased by 50 mg twice weekly based on tolerability and response. The recommended maintenance dose typically ranges from 100 mg to 200 mg twice daily (200 mg to 400 mg per day). It can be taken with or without food. Tablets should be swallowed whole and not crushed, broken, or chewed.

What are the possible side effects of LACOSET 150 MG TABLET?

Common side effects of LACOSET 150 MG TABLET include dizziness, headache, nausea, vomiting, double vision (diplopia), blurred vision, fatigue, sleepiness, unsteadiness, problems with coordination, dry mouth, and muscle spasms. More serious, though rare, side effects can include heart rhythm problems (such as a fast, slow, or irregular heartbeat), and in some cases, it may increase the risk of suicidal thoughts or behaviors. If you experience any severe or persistent side effects, or changes in mood, contact your doctor immediately.

Is LACOSET 150 MG TABLET safe during pregnancy or breastfeeding?

LACOSET 150 MG TABLET (lacosamide) is generally not recommended during pregnancy or breastfeeding. Lacosamide is classified as Pregnancy Category C, meaning caution is advised as potential risks to the fetus cannot be ruled out. Limited studies suggest a relative safety profile during pregnancy and breastfeeding, but further research is needed. It is known to pass into human breast milk. Your doctor will weigh the potential benefits against the risks and decide if it is appropriate for you.

Can LACOSET 150 MG TABLET be taken with other medications?

LACOSET 150 MG TABLET can interact with various medications. It should be used with caution if you are taking drugs that slow your heart rate, such as antiarrhythmics, beta blockers, or calcium channel blockers, as this can increase the risk of heart rhythm problems. Other anti-seizure medications like phenytoin, carbamazepine, and phenobarbital may reduce lacosamide levels, potentially requiring dosage adjustments. Alcohol and sedatives should be avoided as they can increase dizziness and drowsiness. Always inform your doctor about all other medications, supplements, and herbal products you are taking.

What precautions should be taken while taking LACOSET 150 MG TABLET?

Take LACOSET 150 MG TABLET exactly as prescribed by your doctor and do not stop taking it suddenly, as this can lead to an increase in seizure frequency. Exercise caution if you have a history of heart problems (e.g., heart block, heart failure), depression, or suicidal thoughts, as this medication may worsen these conditions. It may cause dizziness, sleepiness, or blurred vision, so avoid driving or operating heavy machinery until you know how it affects you. Dosage adjustments may be necessary for patients with liver or kidney impairment.

What happens if a dose of LACOSET 150 MG TABLET is missed?

If you miss a dose of LACOSET 150 MG TABLET, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one. Consistent dosing is important for seizure control.

How should LACOSET 150 MG TABLET be stored?

LACOSET 150 MG TABLET should be stored in a closed container at room temperature, typically between 20° to 25°C (68° to 77°F), away from heat, moisture, and direct light. Keep all medicines out of the reach of children. If using the oral solution, discard any unused portion after seven weeks of opening the bottle.