Lanzoped Tab

LANZOPED TAB

LANZOPED TAB is a medication primarily used to reduce the amount of acid produced in the stomach. It is a proton pump inhibitor (PPI), working by blocking the action of an enzyme responsible for acid production in the stomach lining.

Composition

• Active Ingredient: Lansoprazole

Uses

LANZOPED TAB, containing Lansoprazole, is prescribed for the treatment and management of various acid-related conditions affecting the stomach and esophagus:

• Acidity and Heartburn: Relieves symptoms of acid reflux.
• Gastroesophageal Reflux Disease (GERD): Addresses acid reflux symptoms like heartburn, regurgitation, and chest discomfort by lowering stomach acid production. It also promotes healing of the esophagus in cases of chronic acid exposure or erosive esophagitis.
• Peptic Ulcer Disease: Treats both gastric (stomach) and duodenal ulcers. It can also be used to prevent and treat stomach ulcers caused by the prolonged use of pain-killers (NSAIDs).
• Zollinger-Ellison Syndrome (ZES): A rare condition characterized by excessive stomach acid production.
• Helicobacter pylori (H. pylori) Infection: Used in combination with antibiotics for the eradication of this bacterial infection.

Dosage and Administration

• LANZOPED TAB is typically taken once a day, preferably in the morning, on an empty stomach.
• It should be swallowed whole with water, at least one hour before a meal, and should not be chewed or crushed.
• If taken twice a day, one dose is usually in the morning and one in the evening.
• The specific dose and duration depend on the condition being treated and the patient's response to the medicine. For instance, typical adult dosages may range from 15 mg to 30 mg once daily for conditions like duodenal ulcers or GERD, while higher doses may be used for hypersecretory conditions.

Side Effects

Common side effects are generally mild and may include:

• Headache
• Diarrhea (may be severe in some cases, caused by C. difficile infection)
• Abdominal pain
• Nausea
• Constipation
• Dizziness

Serious, long-term side effects (especially with use beyond 3 months to a year) can include:

• Low magnesium levels in the blood, leading to fatigue, confusion, dizziness, shakiness, muscle twitches, or irregular heartbeat.
• Increased risk of bone fractures (e.g., hip, wrist, spine) due to decreased calcium levels.
• Vitamin B12 deficiency, causing fatigue, weakness, or paleness.
• Kidney damage
• Severe allergic reactions

Precautions

• Allergies: Inform your doctor if you have had an allergic reaction to Lansoprazole or similar medicines.
• Liver Problems: Use with caution in patients with severe liver problems; dosage adjustment may be necessary.
• Other Medications: Inform your doctor about all medications, especially HIV medicines, digoxin, methotrexate, warfarin, or antifungal medicines, as LANZOPED TAB can interact with them.
• Pregnancy and Breastfeeding: Generally not recommended during pregnancy; consult a doctor.
• Long-term Use: Long-term use (over 1 year) may increase the risk of bone fractures and vitamin B12 deficiency. Discuss calcium and vitamin D supplementation with your doctor to prevent bone loss.
• Phenylketonuria (PKU): Orally disintegrating tablets may contain phenylalanine.
• Avoid foods that trigger acidity, such as fried or spicy foods, butter, oil, and caffeinated drinks.

Storage

• Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.
• Keep out of reach of children.

What is LANZOPED TAB used for?

LANZOPED TAB, which contains the active ingredient lansoprazole, is primarily used to reduce stomach acid. It treats various conditions such as indigestion, heartburn, acid reflux, and gastroesophageal reflux disease (GERD). It is also prescribed to prevent and treat stomach ulcers, including those caused by NSAID use, and to help eradicate Helicobacter pylori (H. pylori) infections in combination with antibiotics. Additionally, it is used for hypersecretory conditions like Zollinger-Ellison syndrome.

How does LANZOPED TAB work?

LANZOPED TAB belongs to a class of medications called proton pump inhibitors (PPIs). It works by irreversibly binding to the hydrogen-potassium adenosine triphosphatase (H+/K+-ATPase) enzyme system, also known as the gastric acid pump, located in the secretory surface of gastric parietal cells. By inhibiting this proton pump, it blocks the final step of acid production in the stomach, thereby reducing the amount of acid your stomach makes.

What is the usual dosage for LANZOPED TAB?

The dosage of LANZOPED TAB (lansoprazole) varies depending on the condition being treated and is usually taken once a day, preferably in the morning before a meal. For indigestion, acid reflux, and stomach ulcers, typical doses range from 15mg to 30mg daily. For Zollinger-Ellison syndrome, the starting dose is often 60mg once a day, which can be adjusted up to 120mg daily. When treating H. pylori infections, it's typically taken as part of a triple therapy regimen, usually 30mg twice a day with antibiotics for 10 to 14 days.

What are the possible side effects of LANZOPED TAB?

Common side effects of LANZOPED TAB include headache, diarrhea, constipation, nausea, and abdominal pain. More serious, but less common, side effects can include low blood magnesium levels, bone fractures (especially with long-term use or high doses), Clostridioides difficile infection (severe diarrhea), kidney problems, and vitamin B12 deficiency (with long-term use). Some individuals may also experience allergic reactions or, in rare cases, skin rashes that can be a sign of lupus.

Is LANZOPED TAB safe during pregnancy or breastfeeding?

LANZOPED TAB (lansoprazole) is generally not recommended during pregnancy due to limited information regarding its use in pregnant individuals. Your doctor may suggest alternative medications like omeprazole, for which more safety data is available. While lansoprazole is excreted in human milk, it's not expected to pass in significant amounts, and any amount that does is likely to be degraded in the infant's gastrointestinal tract. However, omeprazole or pantoprazole are often preferred during breastfeeding due to more established safety profiles.

Can LANZOPED TAB be taken with other medications?

LANZOPED TAB can interact with several other medications. It's crucial to inform your doctor about all medicines, vitamins, minerals, and herbal supplements you are taking. Some medications that may interact with lansoprazole include:

• Digoxin: Lansoprazole can increase digoxin levels, raising the risk of side effects.
• Antifungal medicines (e.g., itraconazole, ketoconazole): Lansoprazole can affect their absorption.
• Methotrexate: Lansoprazole can increase methotrexate levels, leading to more side effects.
• HIV medicines (e.g., atazanavir, nelfinavir): Lansoprazole can decrease their effectiveness.
• Warfarin: May increase the risk of bleeding.
• Sucralfate: Should be taken at least 30 minutes after lansoprazole as it can reduce lansoprazole's effectiveness.
• St. John's Wort and Rifampin: Can reduce the effectiveness of lansoprazole.

What precautions should be taken while using LANZOPED TAB?

Before taking LANZOPED TAB, inform your doctor if you have liver problems, a history of allergic reactions to PPIs, low levels of magnesium or vitamin B12, osteoporosis, or an autoimmune disease like lupus. Long-term use (over 3 months to a year or more) can increase the risk of low magnesium levels, bone fractures, and vitamin B12 deficiency. If you are aged 70 or older, do not take non-prescription lansoprazole for longer than recommended without consulting a doctor.

What happens if a dose of LANZOPED TAB is missed?

If you miss a dose of LANZOPED TAB, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a forgotten one.

How should LANZOPED TAB be stored?

LANZOPED TAB should be stored in a closed container at room temperature, typically between 68°F to 77°F (20°C to 25°C). Keep it away from heat, moisture, and direct light. It's important to keep this medicine, and all medicines, out of the reach of children. Do not store it in moist or damp areas like bathrooms or kitchens.