Clarinova 500 Tablet

CLARINOVA 500 TABLET

Clarinova 500 Tablet, manufactured by Mankind Pharma Ltd., is an antibiotic medication used to treat various bacterial infections.

• Name:

  • Brand Name: Clarinova 500 Tablet
  • Common Name: Clarithromycin (active ingredient)

• Composition:

  • Clarinova 500 Tablet contains Clarithromycin 500 mg as its active ingredient. It belongs to the macrolide class of antibiotics.

• Uses: Clarinova 500 Tablet is prescribed for a wide range of bacterial infections, including:

  • Respiratory tract infections (e.g., bronchitis, pneumonia, sinusitis, tonsillitis, pharyngitis)
  • Ear, nose, and throat infections
  • Skin and soft tissue infections (e.g., cellulitis)
  • Helicobacter pylori (H. pylori) infection, which is associated with peptic ulcer disease
  • Mycobacterium avium complex (MAC) infections in individuals with reduced immunity.

• Dosage and Administration:

  • The dosage and duration are as advised by your doctor based on the severity of the condition.
  • Swallow the tablet whole with a glass of water; do not chew, crush, or break it.
  • It can be taken orally, preferably one hour before or two hours after a meal, or with or without food as advised by your doctor.
  • Maintain regular intervals between each dose and complete the full course of treatment, even if symptoms improve, to prevent recurrence and antibiotic resistance.
  • Do not take antacids within two hours of taking Clarinova 500 Tablet as they can interfere with absorption.

• Side Effects: Common side effects may include:

  • Diarrhea
  • Nausea
  • Vomiting
  • Abdominal pain/Indigestion/Dyspepsia
  • Headache
  • Rash
  • Taste change (metallic taste)
  • Insomnia (difficulty in sleeping)

  Serious side effects are rare but can include liver issues, severe allergic reactions, or irregular heartbeat (QT prolongation). Consult a doctor if these or any other severe or persistent side effects occur.

• Precautions:

  • Inform your doctor about any previous history of allergy to clarithromycin or other macrolide antibiotics.
  • Caution is advised in patients with kidney or liver problems; dose adjustments may be necessary.
  • Not recommended during pregnancy unless clearly necessary and advised by a doctor.
  • Consult your doctor if breastfeeding, as clarithromycin may pass into breast milk.
  • Avoid alcohol consumption as it may worsen side effects like dizziness.
  • This medicine may cause dizziness, headache, or affect vision; avoid driving or operating machinery if affected.
  • Inform your doctor about all other medications you are taking, especially other drugs that can cause abnormal heart rhythms (e.g., terfenadine, astemizole, cisapride, pimozide), statins, ergot alkaloids, benzodiazepines, antidiabetic medications, warfarin, and medications for epilepsy or asthma, due to potential drug interactions.
  • Do not use in children below 12 years of age without consulting a doctor.

• Storage:

  • Store below 30°C in the original packaging.
  • Keep in a cool and dry place away from sunlight.
  • Keep out of sight and reach of children.
  • Do not use after the expiry date.

CLARINOVA 500 TABLET contains Clarithromycin 500 mg as its active ingredient. It is a macrolide antibiotic used to treat a variety of bacterial infections.

What is CLARINOVA 500 TABLET used for?

CLARINOVA 500 TABLET is used to treat a wide range of bacterial infections in different parts of the body. These include respiratory tract infections (like pneumonia, bronchitis, sinusitis), ear infections, throat infections (pharyngitis, tonsillitis), and skin and soft tissue infections (such as cellulitis). It is also used in combination with other medicines to treat stomach ulcers caused by the bacterium Helicobacter pylori.

How does CLARINOVA 500 TABLET work?

The active ingredient, clarithromycin, works by stopping the growth of bacteria. It achieves this by binding to the 50S ribosomal subunit within the bacteria, which is essential for protein synthesis. By disrupting this process, clarithromycin prevents bacteria from producing the proteins they need to grow and multiply, thereby helping the body's immune system clear the infection.

What is the usual dosage of CLARINOVA 500 TABLET?

For adults, the usual dosage for bacterial infections is typically 250 mg to 500 mg twice a day for 7 to 14 days. For severe infections, the dose may be increased to 500 mg twice daily. When used to treat ulcers associated with H. pylori, it is often prescribed as 500 mg every 8 to 12 hours for 10 to 14 days, in combination with other medications. The exact dose and duration of treatment will depend on the type and severity of the infection, and it should always be taken as prescribed by your doctor.

What are the possible side effects of CLARINOVA 500 TABLET?

Common side effects can include nausea, vomiting, diarrhea, abdominal pain, headache, and an altered sense of taste (often described as metallic). Other possible side effects include indigestion, heartburn, rash, and difficulty sleeping (insomnia). Less common but serious side effects can include severe allergic reactions, liver problems (e.g., jaundice, dark urine), and irregular heartbeats (QT prolongation). If you experience severe or persistent side effects, or signs of an allergic reaction, seek medical attention immediately.

Is CLARINOVA 500 TABLET safe during pregnancy or breastfeeding?

Clarithromycin is generally not recommended for use during pregnancy unless there are no safer alternatives and the potential benefits outweigh the risks to the fetus. Animal studies have shown adverse effects on the fetus. If you are pregnant or planning to become pregnant, discuss this with your doctor.

Regarding breastfeeding, clarithromycin passes into breast milk in small amounts. While generally considered unlikely to cause harm, caution is advised. Breastfed infants should be monitored for potential side effects such as diarrhea, candidiasis (thrush or diaper rash), rash, upset stomach, or unusual sleepiness. It is important to consult your doctor or health visitor if you are breastfeeding and considering or taking this medication.

Can CLARINOVA 500 TABLET be taken with other medications?

Clarithromycin can interact with many other medications, and some combinations should be avoided. Severe interactions can occur with certain drugs like pimozide, cisapride, ergotamine, dihydroergotamine, and some statins (e.g., simvastatin, lovastatin) due to an increased risk of serious side effects, including muscle problems and heart issues. It also interacts with medications for heart conditions, diabetes, and gout (like colchicine). Always inform your doctor and pharmacist about all prescription, non-prescription, vitamin, nutritional supplements, and herbal products you are taking or plan to take to check for potential interactions.

What precautions should be taken while taking CLARINOVA 500 TABLET?

Before taking CLARINOVA 500 TABLET, inform your doctor if you have any allergies (especially to macrolide antibiotics like erythromycin or azithromycin), liver or kidney problems, or a history of heart conditions such as QT prolongation or abnormal heart rhythms. It's crucial to complete the full prescribed course of treatment, even if you start feeling better, to prevent the infection from returning and to reduce the risk of antibiotic resistance. Do not share this medicine with others.

What happens if a dose of CLARINOVA 500 TABLET is missed?

If you miss a dose, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a forgotten one.

How should CLARINOVA 500 TABLET be stored?

CLARINOVA 500 TABLET (clarithromycin tablets) should be stored at room temperature, generally between 20°C to 25°C (68°F to 77°F). Keep the medicine in its original container, tightly closed, and protect it from light. It should be kept out of reach of children. Do not store it in the bathroom or kitchen, as heat and moisture can reduce its effectiveness.