Ctd - O 12.5 / 20

CTD-O 12.5/20 Tablet

Name

• Brand Name: CTD-O 12.5/20 Tablet
• Manufacturer: IPCA LABORATORIES LTD

Composition CTD-O 12.5/20 Tablet is a combination medication containing two active ingredients:

• Olmesartan Medoxomil (20 mg)
• Chlorthalidone (12.5 mg)

Uses This medication is primarily used for the management of essential hypertension (high blood pressure). It is often prescribed when a single medicine is not effective in controlling blood pressure. By controlling blood pressure, CTD-O 12.5/20 helps to prevent serious cardiovascular events such as heart attacks, strokes, and kidney problems.

Dosage and Administration CTD-O 12.5/20 Tablet should be taken orally as directed by your doctor, usually once daily. It can be taken with or without food. The tablet should be swallowed whole with a glass of water and not chewed, crushed, or broken. To ensure consistent effectiveness, it is important to take the medicine at the same time each day. Due to its diuretic component, which increases urination, it is advisable to avoid taking this medication within four hours of bedtime. Do not stop taking the medicine suddenly without consulting your doctor, as this can lead to a rise in blood pressure and increased risk of heart attack or stroke.

Side Effects Common side effects may include:

• Headache, dizziness, tiredness, fatigue
• Nausea, indigestion, diarrhea, stomach pain
• Sore throat, runny nose, flu-like symptoms, cough
• Chest pain, back pain, joint pain
• Urinary tract infection
• Swelling of the feet, ankles, hands, or arms
• Skin rash
• Orthostatic hypertension (feeling dizzy while standing up)
• Loss of appetite, impotence in men

Serious side effects, though rare, warrant immediate medical attention, such as severe allergic reactions (skin rash, itching, swelling of the face, mouth, and/or larynx) and severe hypotension (low blood pressure) with light-headedness or fainting. The medication may also cause an increase in uric acid, blood lipid levels, and potassium levels, as well as electrolyte imbalances, decreased blood pressure, renal dysfunction, and abnormal liver function tests.

Precautions

• Medical Conditions: Inform your doctor if you have diabetes, liver, kidney, or heart disease. Caution is advised for patients with severe kidney problems, kidney failure, lack of urine, kidney stones, hyperuricaemia, hyperlipidaemia, or volume depletion.
• Pregnancy and Breastfeeding: CTD-O 12.5/20 Tablet is not recommended for use in pregnant or breastfeeding women as it can cause serious harm to the baby.
• Children: This medicine is not recommended for children and adolescents under 18 years of age due to a lack of safety data.
• Alcohol and Driving: Avoid alcohol consumption while taking this medication as it can intensify blood pressure-lowering effects. Do not drive or operate heavy machinery if you experience dizziness, sleepiness, or tiredness.
• Interactions: Inform your doctor about all other medicines, supplements, or herbal products you are taking. Significant interactions can occur with lithium, NSAIDs, dual blockade of the Renin-Angiotensin system (e.g., enalapril, lisinopril), potassium supplements, corticosteroids, ACTH, barbiturates, and narcotics. Avoid grapefruit or grapefruit juice.
• Monitoring: Your doctor may regularly check your blood pressure, kidney function, and electrolyte balance during treatment.

Storage Store CTD-O 12.5/20 Tablets in a cool and dry place, away from direct sunlight, and below 30°C. Keep out of sight and reach of children and pets.

CTD-O 12.5/20 is a combination medication containing Olmesartan Medoxomil (20mg) and Chlorthalidone (12.5mg), manufactured by Ipca Laboratories Ltd.. It is primarily used to treat high blood pressure.

Here are some frequently asked questions about CTD-O 12.5/20:

What is CTD-O 12.5/20 used for?

CTD-O 12.5/20 is used to treat high blood pressure, also known as hypertension. This medication helps to lower elevated blood pressure, which in turn reduces the risk of serious cardiovascular complications such as heart attacks, strokes, and kidney damage. It is often prescribed when a single medication is not effective enough in controlling blood pressure.

How does CTD-O 12.5/20 work?

This medicine works through the combined action of its two active ingredients: Olmesartan Medoxomil and Chlorthalidone. Olmesartan Medoxomil is an angiotensin receptor blocker (ARB) that works by relaxing and widening blood vessels, allowing blood to flow more easily and reducing pressure on the heart. Chlorthalidone is a diuretic, also known as a "water pill," which increases the amount of urine your body produces, helping to remove excess fluid and salt from the body and thereby lowering blood pressure. Together, they effectively reduce blood pressure and improve blood flow.

What is the usual dosage of CTD-O 12.5/20?

The typical dosage for adults is one tablet once daily. Your doctor will determine the exact dosage based on your medical condition and response to treatment. It is important to take the tablet at the same time each day for optimal effect and to swallow it whole with a glass of water without crushing, chewing, or breaking it.

What are the common side effects of CTD-O 12.5/20?

Common side effects may include dizziness, headache, nausea, diarrhea, fatigue, increased urination, muscle cramps, and low blood pressure (hypotension). Dizziness is a particularly common side effect. Most side effects are usually mild and temporary.

Are there any serious side effects to be aware of?

Although rare, serious side effects can occur, including severe allergic reactions (swelling of the face, throat, tongue, or lips), significant drops in blood pressure, electrolyte imbalances (such as low sodium or potassium), kidney dysfunction, and severe diarrhea with weight loss. If you experience any severe or persistent symptoms, seek medical attention immediately.

Is CTD-O 12.5/20 safe during pregnancy or breastfeeding?

CTD-O 12.5/20 (Olmesartan and Chlorthalidone) is not recommended during the first trimester of pregnancy and is contraindicated during the second and third trimesters, as it can cause injury or death to the unborn baby. If you become pregnant, stop taking this medicine and inform your doctor right away.

For breastfeeding, it is generally advised to consult your doctor. Chlorthalidone can pass into breast milk and may also suppress lactation. There is limited information on Olmesartan's presence in breast milk, and an alternative drug may be preferred, especially for newborns or preterm infants.

Can CTD-O 12.5/20 be taken with other medications?

CTD-O 12.5/20 can interact with several other medications. It should not be taken with grapefruit, grapefruit juices, or St. John's wort. Caution is advised when taken with other blood pressure-lowering medications (like ACE inhibitors or Aliskiren, especially in diabetic patients or those with kidney impairment), NSAIDs (e.g., ibuprofen, naproxen), lithium, potassium supplements, or potassium-sparing diuretics. Always inform your doctor about all medicines, supplements, and herbal products you are taking to avoid potential interactions.

What precautions should be taken while using CTD-O 12.5/20?

Inform your doctor if you have low blood pressure, kidney disease, liver disease, heart valve problems (stenosis), heart failure, or a history of gout or diabetes. This medication may cause dizziness, so avoid driving or operating heavy machinery until you know how it affects you. Regular monitoring of blood pressure, kidney function, and electrolyte levels may be advised. It is important not to stop taking this medicine suddenly, as it can lead to a sudden rise in blood pressure.

What should I do if I miss a dose of CTD-O 12.5/20?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

How should CTD-O 12.5/20 be stored?

Store the medicine in a cool and dry place, away from direct sunlight, heat, and moisture. Keep it out of sight and reach of children.