Aceclo Sr Tablets

ACECLO SR TABLETS

ACECLO SR TABLETS, manufactured by Aristo Pharmaceuticals Private Limited, is a sustained-release medication primarily used for pain relief and reduction of inflammation.

• Composition The active ingredient in ACECLO SR TABLETS is Aceclofenac (200 mg). It is a non-steroidal anti-inflammatory drug (NSAID) that works by blocking the production of prostaglandins, chemicals in the body responsible for pain, inflammation, and fever.

• Uses ACECLO SR TABLETS are prescribed for the management of pain, stiffness, and swelling associated with various conditions affecting joints and muscles. These include:

  • Rheumatoid arthritis
  • Osteoarthritis
  • Ankylosing spondylitis
  • Short-term relief from general pain such as headaches, body aches, toothaches, backaches, menstrual pain, sprains, and strains.

• Dosage and Administration The typical recommended dose for adults is one 200 mg Aceclofenac SR tablet daily, or as prescribed by a physician. The tablet should be swallowed whole with a glass of water and not crushed or chewed. It is generally advised to take this medicine with food or milk to minimize potential stomach discomfort. The dosage and duration of treatment should always be as directed by a doctor.

• Side Effects Common side effects may include nausea, vomiting, diarrhoea, stomach upset, indigestion, abdominal pain, headache, and dizziness. More serious side effects can include severe allergic reactions, severe skin rashes (like Stevens-Johnson Syndrome), meningitis, and kidney failure, as well as gastrointestinal bleeding or ulcers, especially with long-term use.

• Precautions ACECLO SR TABLETS are contraindicated in pregnancy, particularly during the third trimester, and caution is advised during breastfeeding. It should be used with caution or is contraindicated in patients with a history of stomach ulcers, bleeding disorders, severe liver or kidney disease, heart disease, or uncontrolled hypertension. Alcohol consumption should be avoided as it may increase the risk of side effects like dizziness and stomach bleeding. This medicine may cause dizziness or drowsiness, so caution is advised when driving or operating machinery. Inform your doctor about any other medications, supplements, or pre-existing conditions as interactions can occur with anticoagulants, diuretics, lithium, methotrexate, mifepristone, and steroids. Long-term treatment may require regular monitoring of kidney function, liver function, and blood component levels.

• Storage Store ACECLO SR TABLETS in a cool, dry place, at room temperature below 30°C (or 25°C), away from direct light and moisture. Keep the medicine out of reach of children.

Here are some frequently asked questions about ACECLO SR TABLETS:

What is ACECLO SR TABLET used for?

ACECLO SR TABLET is a non-steroidal anti-inflammatory drug (NSAID) primarily used to relieve pain, swelling, and inflammation associated with various musculoskeletal conditions. These include osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis (a type of arthritis affecting the spine). It can also be used for other types of pain such as toothache, trauma, lumbago, and post-operative pain.

How does ACECLO SR TABLET work?

ACECLO SR TABLET contains Aceclofenac, which works by blocking the action of an enzyme called cyclo-oxygenase (COX) in the body. COX enzymes are responsible for producing prostaglandins, chemical messengers that cause pain, swelling, and inflammation at sites of injury or disease. By inhibiting these enzymes, Aceclofenac reduces the production of prostaglandins, thereby alleviating pain and inflammation.

What is the usual dosage for ACECLO SR TABLET?

For adults, the recommended dose for Aceclofenac sustained-release (SR) tablets, such as ACECLO SR TABLET, is typically one 200 mg tablet once daily. It should be swallowed whole with water and not crushed or chewed. It is generally advised to take this medicine with or after food to help minimize the risk of stomach upset. Always follow your doctor's prescribed dosage and duration of treatment.

What are the possible side effects of ACECLO SR TABLET?

Common side effects can include gastrointestinal discomfort such as nausea, vomiting, diarrhea, flatulence, constipation, abdominal pain, indigestion, and heartburn. Other side effects may include skin rashes, dizziness, and visual disturbances (blurry vision). If you experience severe side effects like gastrointestinal bleeding (black or bloody stools, vomiting blood), severe abdominal pain, or allergic reactions (swelling of face/mouth, breathing difficulties), seek immediate medical attention. Long-term use or high doses can increase the risk of serious complications, including stomach bleeding, ulcers, and kidney problems.

Is ACECLO SR TABLET safe during pregnancy or breastfeeding?

ACECLO SR TABLET is generally not recommended during pregnancy, especially in the third trimester, as it may pose risks to the fetus, including cardiopulmonary toxicity and renal dysfunction. It should be avoided unless the potential benefits clearly outweigh the possible risks, and any use during the first or second trimester should be at the lowest effective dose for the shortest possible duration under strict medical supervision.

For breastfeeding, ACECLO SR TABLET should also be avoided unless deemed necessary by a doctor. While data on its excretion into breast milk is limited, its high protein-binding capacity suggests that amounts in milk are likely to be very low. However, an alternative drug may be preferred, particularly for newborns or preterm infants.

Can ACECLO SR TABLET be taken with other medications?

You should not take ACECLO SR TABLET with other NSAIDs (including aspirin and COX-2 selective inhibitors) unless specifically prescribed by your doctor, as this can increase the risk of gastrointestinal bleeding and other adverse reactions.

It may interact with certain medications, including:

• Blood thinners (anticoagulants like warfarin): May increase the risk of bleeding.
• Diuretics and antihypertensives: May reduce their effectiveness and affect kidney function.
• Lithium and methotrexate: May increase their plasma concentrations, potentially leading to toxicity.
• Corticosteroids: Can heighten the risk of gastrointestinal ulcers or bleeding. Always inform your doctor about all other medications you are taking, including over-the-counter drugs and herbal supplements, to avoid potential interactions.

What precautions should be taken while taking ACECLO SR TABLET?

• Stomach Upset: Always take the tablet with food or milk to minimize stomach irritation.
• Pre-existing Conditions: Inform your doctor if you have a history of stomach ulcers, gastrointestinal bleeding, asthma, heart disease (including heart failure, hypertension), kidney or liver impairment, or bleeding disorders.
• Alcohol Consumption: Avoid alcohol as it can increase drowsiness and significantly raise the risk of stomach bleeding and liver stress.
• Driving/Operating Machinery: This medicine may cause dizziness, drowsiness, or visual disturbances; avoid driving or operating machinery if you experience these effects.
• Long-term Use: Long-term treatment may require regular monitoring of kidney function, liver function, and blood counts.

What happens if a dose is missed?

If you forget to take a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the forgotten one, as this can increase the risk of side effects.

How should ACECLO SR TABLET be stored?

Store ACECLO SR TABLET in a dry and cool place, away from direct light and heat. Ensure it is kept out of the reach and sight of children. The storage temperature should generally not exceed 30°C.