Liralin Ep 25mg Tab

LIRALIN EP 25MG TABLET

LIRALIN EP 25MG Tablet is a combination medication manufactured by USV Private Limited, primarily used for the management of Type 2 Diabetes Mellitus. It combines two active ingredients that work through different mechanisms to help control blood sugar levels.

Composition

• Active Ingredients: Each tablet contains Empagliflozin 25 mg and Linagliptin 5 mg.

Uses

LIRALIN EP 25MG Tablet is prescribed for adults with Type 2 Diabetes Mellitus to improve blood sugar (glucose) control. It is typically used as an adjunct to diet and exercise when lifestyle modifications alone are not sufficient. By managing blood sugar levels, it also helps reduce the risk of serious complications associated with diabetes, such as kidney damage, eyesight problems (retinopathy), nerve damage (neuropathy), and diabetic foot ulcer, and may also lower the risk of cardiovascular events in patients with Type 2 diabetes and established cardiovascular disease.

• Mechanism of Action:
  • Empagliflozin (an SGLT-2 inhibitor) works by increasing the removal of sugar from the body through urine via the kidneys.
  • Linagliptin (a DPP-4 inhibitor) increases levels of natural substances called incretins, which help regulate blood sugar by stimulating insulin release, particularly after meals, and decreasing the amount of sugar the liver produces.

Dosage and Administration

LIRALIN EP 25MG Tablet should be taken orally once daily, with or without food, as directed by a doctor. It is important to take the tablet at the same time each day for consistent results and to swallow it whole without crushing or chewing. Patients should not stop taking the medication without consulting their doctor.

Side Effects

Common side effects may include:

• Urinary tract infections (UTIs)
• Nasopharyngitis (inflammation of the throat and nasal passages)
• Genital fungal infections
• Hypoglycemia (low blood sugar level), especially when taken with other diabetes medications like insulin or sulfonylureas.
• Nausea
• Dizziness or lightheadedness
• Fatigue
• Cough
• Constipation

Serious side effects can include yellowing of skin/eyes (jaundice), severe abdominal pain, unusual vaginal bleeding, or allergic reactions. Patients should seek immediate medical help if serious side effects occur.

Precautions

• Allergies: Do not take LIRALIN EP 25MG Tablet if allergic to empagliflozin, linagliptin, or any of its ingredients.
• Kidney and Liver Disease: Use with caution in patients with kidney problems, and it is not recommended in severe liver impairment or severe kidney disease. Dosage adjustments may be necessary.
• Pregnancy and Breastfeeding: Generally not advised during pregnancy or while breastfeeding.
• Alcohol: Limit alcohol intake, as excessive consumption can affect blood sugar control and increase the risk of low blood sugar or dehydration.
• Dehydration: Drink plenty of fluids to help prevent dehydration.
• Type 1 Diabetes: This medication is specifically for Type 2 Diabetes and is not recommended for individuals with Type 1 Diabetes or diabetic ketoacidosis.
• Interactions: Inform your doctor about all medicines, supplements, or herbals being taken to avoid possible interactions. Taking LIRALIN EP with insulin or sulfonylureas may increase the risk of hypoglycemia.

Storage

Store in a cool and dry place away from sunlight, preferably below 30°C. Keep out of the sight and reach of children.

What is LIRALIN EP 25MG TAB used for?

LIRALIN EP 25MG TAB is primarily used for the management of Type 2 Diabetes Mellitus in adults. It helps control high blood sugar levels when used alongside diet and exercise. It may also reduce the risk of cardiovascular events and helps prevent complications of diabetes such as kidney damage, eye damage, and nerve problems.

How does LIRALIN EP 25MG TAB work?

LIRALIN EP 25MG TAB is a fixed-dose combination medication containing Linagliptin and Empagliflozin. Empagliflozin (an SGLT-2 inhibitor) works by blocking the reabsorption of glucose in the kidneys, leading to its elimination through urine, thereby lowering blood sugar. Linagliptin (a DPP-4 inhibitor) increases the release of insulin and decreases glucose production, particularly when blood sugar levels are high after a meal.

What is the usual dosage for LIRALIN EP 25MG TAB?

LIRALIN EP 25MG TAB is typically taken orally once daily, with or without food, as directed by your doctor. It is important to follow your doctor's instructions and take it at the same time each day for consistent results. Do not stop taking the medicine without consulting your doctor.

What are the possible side effects of LIRALIN EP 25MG TAB?

Common side effects may include hypoglycemia (low blood sugar), increased thirst, genital yeast infections, urinary tract infections, increased urination, nasopharyngitis (inflammation of the throat and nasal passages), and upper respiratory tract infections. Other potential side effects are cough, constipation, nausea, and dizziness.

Is LIRALIN EP 25MG TAB safe during pregnancy or breastfeeding?

LIRALIN EP 25MG TAB is not recommended for use during pregnancy or while breastfeeding. It is advised to consult your doctor for alternative treatment options if you are pregnant, planning a pregnancy, or breastfeeding.

Can LIRALIN EP 25MG TAB be taken with other medications?

Yes, LIRALIN EP 25MG TAB can be used in conjunction with other diabetes medications if prescribed by your doctor. However, close monitoring of blood sugar levels is crucial, especially if taken with insulin or sulfonylureas, as this can increase the risk of hypoglycemia. It is important to inform your doctor about all other medications, supplements, or herbals you are taking to avoid potential interactions. Do not discontinue any medication without consulting your doctor.

What precautions should be taken while using LIRALIN EP 25MG TAB?

LIRALIN EP 25MG TAB should be used with caution in patients with kidney problems, and dosage adjustments may be necessary. It is important to stay well-hydrated to prevent dehydration. Patients should maintain good genital hygiene to prevent yeast or urinary tract infections. Avoid excessive alcohol intake, as it can affect blood sugar control and increase the risk of certain side effects. This medication is not for Type 1 diabetes or diabetic ketoacidosis. Close monitoring of renal function and blood sugar levels is advised for elderly patients.

What happens if a dose of LIRALIN EP 25MG TAB is missed?

If you miss a dose, take it as soon as you remember. However, if it is close to the time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

How should LIRALIN EP 25MG TAB be stored?

LIRALIN EP 25MG TAB should be stored in a cool and dry place, typically below 30°C. It should be protected from moisture and sunlight, and kept out of the sight and reach of children.