Glycobreez F Dpi Cap

GLYCOBREEZ F DPI CAP

GLYCOBREEZ F DPI CAP is a combination medication manufactured by Mankind Pharma Ltd., used for the long-term maintenance treatment of chronic obstructive pulmonary disease (COPD).

Composition

Each GLYCOBREEZ F DPI CAP contains a fixed-dose combination of two active ingredients:

• Glycopyrrolate: 25.00 MCG (also referred to as Glycopyrronium bromide 25 MCG)
• Formoterol Fumarate: 12.00 MCG (also referred to as Formoterol 12mcg or Formoterol Fumarate 6mcg/25mcg)

Uses

GLYCOBREEZ F DPI CAP is prescribed for the management of chronic obstructive pulmonary disease (COPD). It works by making breathing easier for patients with this condition. Specific uses include:

• Managing symptoms such as bronchospasm, wheezing, and shortness of breath.
• Improving lung function and airflow.
• Reducing mucus production and preventing airway narrowing.
• Long-term maintenance treatment of COPD, chronic bronchitis, and control of emphysema symptoms.
• Prevention of airflow obstruction and COPD exacerbations.

Dosage and Administration

GLYCOBREEZ F DPI CAP is for inhalation only using a special dry powder inhaler device; the capsule should never be swallowed. It should be taken regularly at the same time each day, as prescribed by your doctor, even if symptoms are not present, to ensure effectiveness.

• This medicine does not work immediately and should not be used to relieve sudden breathing problems or acute asthma attacks. A quick-relief inhaler should be used for acute attacks.
• The first dose should be taken under medical supervision, as it may cause immediate wheezing or tightening of the airways (bronchospasm).

Side Effects

Common side effects may include:

• Dry mouth (which can be managed with frequent rinses, good oral hygiene, increased water intake, and sugarless candy)
• Indigestion
• Nasopharyngitis (inflammation of the throat and nasal passages)
• Chest pain
• Fever
• Sore throat
• Cough
• Headache
• Sinus inflammation
• Inflammation of the nose
• Urinary tract infection
• Dizziness
• Increased glucose level in blood
• Urinary retention
• Nausea

Serious side effects can include paradoxical bronchospasm (sudden worsening of breathing after using the inhaler). Seek immediate medical attention for signs of a very bad reaction such as severe wheezing, chest tightness, blue or gray skin color, seizures, or swelling of the face, lips, tongue, or throat.

Precautions

• Allergies: Inform your doctor if you have an allergy to formoterol, glycopyrrolate, or any other ingredients in the medicine, including lactose or milk protein.
• Pregnancy: Use with caution during pregnancy. Animal studies have shown harmful effects on the fetus, and potential benefits should be weighed against risks. Doctor consultation is advised.
• Breastfeeding: Caution is advised. Limited human data suggests no significant risk to the baby, but long-term use might reduce milk production. Doctor consultation is advised.
• Medical Conditions: Inform your doctor if you have infections in your mouth or lungs, liver or kidney disease, narrow-angle glaucoma, urinary retention, heart conditions (arrhythmias, hypertension), or prostate enlargement.
• Driving and Operating Machinery: This medicine may cause dizziness or affect vision and coordination, potentially impairing your ability to drive.
• Alcohol: Avoid consuming alcohol as it may lead to excessive drowsiness.
• Drug Interactions: Beta-blockers, other anticholinergic medicines (e.g., ipratropium, tiotropium), and diuretics may interact with GLYCOBREEZ F DPI CAP.
• Potassium Levels: Your doctor may monitor your blood potassium levels, as COPD medicines and low oxygen levels can lower them.
• Not for Asthma: GLYCOBREEZ F is specifically for COPD and not indicated for acute asthma attacks.

Storage

Store GLYCOBREEZ F DPI CAP in a cool, dry place, away from direct sunlight and excess heat and moisture. Keep it out of reach of children. The recommended storage temperature is typically below 30°C or between 10°C to 25°C.

Here are the most frequently asked questions about GLYCOBREEZ F DPI CAP:

What is GLYCOBREEZ F DPI CAP used for?

GLYCOBREEZ F DPI CAP is a combination medicine primarily used to make breathing easier for patients with Chronic Obstructive Pulmonary Disease (COPD). It helps manage symptoms such as bronchospasm, wheezing, and shortness of breath, improving overall lung function and quality of life. It is intended for long-term maintenance treatment and not for relieving sudden acute asthma attacks.

How does GLYCOBREEZ F DPI CAP work?

GLYCOBREEZ F DPI CAP combines two medicines: Formoterol and Glycopyrrolate. Formoterol is a long-acting beta2-adrenergic agonist (LABA) that works by relaxing the smooth muscles surrounding the airways, thereby widening them and improving airflow. Glycopyrrolate is a long-acting muscarinic antagonist (LAMA) or anticholinergic that blocks certain receptors in the airways, reducing mucus secretion and preventing the narrowing of airways. Together, they provide a dual-action approach to relieve symptoms and maintain open airways.

What is the usual dosage for GLYCOBREEZ F DPI CAP?

The dosage of GLYCOBREEZ F DPI CAP should be taken exactly as prescribed by your doctor. It is typically administered as an inhalation using a special dry powder inhaler device, and the capsule should never be swallowed. It is important to take the lowest effective dose needed to control your condition. Do not take it more often than every 12 hours unless specifically instructed by your doctor.

What are the possible side effects of GLYCOBREEZ F DPI CAP?

Common side effects may include dry mouth, headache, sore throat, cough, indigestion, nasopharyngitis (inflammation of the throat and nasal passages), chest pain, fever, sinus inflammation, and urinary tract infection. Other possible side effects include dizziness, increased glucose levels in the blood, and high blood pressure. Dry mouth can often be managed with frequent mouth rinses, good oral hygiene, increased water intake, and sugarless candy. In some cases, paradoxical bronchospasm (sudden worsening of breathing after use) may occur. Your doctor may also monitor your blood potassium levels.

Is GLYCOBREEZ F DPI CAP safe during pregnancy or breastfeeding?

For pregnancy, GLYCOBREEZ F DPI CAP may be unsafe to use. Animal studies have shown harmful effects on the developing baby, and limited human studies exist. Your doctor will weigh the potential benefits against any risks before prescribing it. Regarding breastfeeding, it is generally considered probably safe, as limited human data suggests it does not represent a significant risk to the baby. However, long-term use might reduce milk production. It is crucial to consult your doctor for personalized advice during both pregnancy and breastfeeding.

Can GLYCOBREEZ F DPI CAP be taken with other medications?

There can be potential drug interactions with GLYCOBREEZ F DPI CAP. For instance, beta-blockers (like propranolol or atenolol) may reduce the effectiveness of Formoterol. Taking it with other anticholinergic medicines (like ipratropium or tiotropium) may increase side effects such as dry mouth and urinary retention. Always inform your doctor about all the medications, including over-the-counter drugs and supplements, you are currently taking to avoid potential interactions.

What precautions should be taken while using GLYCOBREEZ F DPI CAP?

This medicine is not meant for immediate relief of sudden breathing problems or acute asthma attacks; use a quick-relief inhaler for such situations. The first dose should be taken under medical supervision, as it may cause wheezing or tightening of the airways immediately after use. Avoid consuming alcohol with this medicine, as it may lead to excessive drowsiness. Patients with a history of cardiovascular conditions or thyroid disorders, narrow-angle glaucoma, urinary retention, or prostate enlargement should use it with caution. If you have infections in your mouth or lungs, or liver or kidney disease, inform your doctor. Do not stop using it without consulting your doctor, even if your symptoms improve.

What happens if a dose of GLYCOBREEZ F DPI CAP is missed?

If you miss a dose of GLYCOBREEZ F DPI CAP, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

How should GLYCOBREEZ F DPI CAP be stored?

GLYCOBREEZ F DPI CAP should be stored at room temperature, away from excess heat and moisture. Keep it out of reach of children.