Glycinorm Total 60

What is GLYCINORM TOTAL 60 used for?

GLYCINORM TOTAL 60 is used to treat Type 2 diabetes mellitus in adults. It helps to control high blood sugar levels when diet, exercise, and treatment with single medications are not enough. This medicine can also help prevent serious diabetes complications like kidney damage, blindness, nerve problems, and loss of limbs.

How does GLYCINORM TOTAL 60 work?

GLYCINORM TOTAL 60 is a combination of three antidiabetic medicines: Gliclazide, Metformin, and Pioglitazone.

• Gliclazide works by stimulating the pancreas to release more insulin.
• Metformin lowers glucose production in the liver, delays glucose absorption from the intestines, and increases the body's sensitivity to insulin.
• Pioglitazone decreases the amount of glucose released by the liver and improves how well tissues like muscles and fats respond to insulin.

What is the usual dosage for GLYCINORM TOTAL 60?

The usual dosage of GLYCINORM TOTAL 60 is determined by your doctor based on your individual needs and response to treatment. It is typically taken orally, once or twice daily, preferably with or immediately after meals to minimize gastrointestinal side effects. You should swallow the tablet whole with a glass of water and not crush, chew, or break it. Never exceed the prescribed dose without consulting your doctor.

What are the possible side effects of GLYCINORM TOTAL 60?

Common side effects can include low blood sugar (hypoglycemia), nausea, vomiting, diarrhea, stomach pain, taste changes, weight gain, headache, dizziness, and respiratory infection. Serious but less common side effects can include lactic acidosis (a build-up of lactic acid in the body) and symptoms of heart failure (like unusual shortness of breath or swelling in the ankles or legs). If you experience severe or persistent side effects, or symptoms of lactic acidosis or heart failure, contact your doctor immediately.

Is GLYCINORM TOTAL 60 safe during pregnancy or breastfeeding?

GLYCINORM TOTAL 60 is generally not recommended for use during pregnancy or breastfeeding. It is advised to consult your doctor for alternative treatment options if you are pregnant, planning to become pregnant, or breastfeeding.

Can GLYCINORM TOTAL 60 be taken with other medications?

GLYCINORM TOTAL 60 can interact with several other medications. It's crucial to inform your doctor about all prescription drugs, over-the-counter medicines, herbal tonics, and supplements you are currently taking. Interactions can occur with other antidiabetic agents (e.g., insulin), pain killers (e.g., aspirin, ibuprofen), certain antibiotics (e.g., ciprofloxacin, chloramphenicol), antifungal agents (e.g., fluconazole), thiazide diuretics, corticosteroids (e.g., prednisolone), and cationic medications.

What precautions should be taken while using GLYCINORM TOTAL 60?

Several precautions should be observed:

• Alcohol: Avoid or limit alcohol consumption as it can increase the risk of low blood sugar and lactic acidosis.
• Medical Conditions: This medicine is not recommended for Type 1 diabetes, diabetic ketoacidosis, severe heart failure, severe kidney or liver disease, or bladder cancer. Use with caution if you have kidney or liver problems, heart disease, or are elderly.
• Driving/Operating Machinery: GLYCINORM TOTAL 60 may cause dizziness or fatigue, so avoid driving or operating heavy machinery if you experience these symptoms.
• Hypoglycemia: Be aware of the symptoms of low blood sugar (sweating, dizziness, headache, shakiness) and carry a fast-acting source of glucose (like sugary food or fruit juice) to manage it.

What happens if a dose of GLYCINORM TOTAL 60 is missed?

If you miss a dose of GLYCINORM TOTAL 60, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

How should GLYCINORM TOTAL 60 be stored?

GLYCINORM TOTAL 60 tablets should be stored at room temperature, ideally below 30°C. Keep them protected from moisture and light, and out of reach of children.