Sgltd S 10/100 Mg Tablet (10 Tab)

SGLTD S 10/100 MG TABLET

Name

• Brand Name: SGLTD S 10/100 MG TABLET
• Manufacturer: MANKIND PHARMA LTD.

Composition SGLTD S 10/100 MG TABLET is a fixed-dose combination medication containing:

• Dapagliflozin: 10 mg (a sodium-glucose cotransporter 2 (SGLT2) inhibitor)
• Sitagliptin: 100 mg (a dipeptidyl peptidase-4 (DPP-4) inhibitor)

Uses This medicine is prescribed for the management of type 2 diabetes mellitus in adults. It is used to help control blood sugar levels when diet, exercise, and other medications alone are not sufficient. SGLTD S 10/100 also helps improve glycemic control and may reduce the risk of heart attack, heart failure, other cardiovascular events, and slow the progression of diabetic and non-diabetic kidney disease.

Dosage and Administration Take SGLTD S 10/100 MG TABLET orally as directed by your doctor, usually once daily with or without food. The tablet should be swallowed whole and not crushed or chewed. It is recommended to take it at the same time each day for optimal benefits. Do not exceed the prescribed dosage or stop taking the medication without consulting your doctor.

Side Effects

• Common Side Effects: Hypoglycemia (low blood sugar), joint pain, increased urination, genital yeast infection, thirst, common cold, headaches, back pain, diarrhea, nausea, urinary tract infections, nasal congestion, sore throat, upper respiratory tract infections, flatulence, constipation, stomach pain, dizziness, and swelling of hands or legs.
• Serious Side Effects: Seek immediate medical attention if you experience severe and persistent stomach pain (possibly indicating an inflamed pancreas), severe allergic reactions (rash, hives, swelling of the face/throat), or symptoms of diabetic ketoacidosis (nausea, vomiting, abdominal pain, excessive thirst, confusion).

Precautions

• Pregnancy and Breastfeeding: Not recommended during the second and third trimesters of pregnancy or while breastfeeding. Consult your doctor for advice.
• Kidney and Liver Conditions: Use with caution in patients with kidney problems or severe liver disease. It is not recommended for individuals with severe kidney impairment, end-stage renal disease, or those on dialysis. Regular monitoring may be necessary.
• Alcohol: Limit alcohol consumption as it may impact blood sugar control.
• Dehydration: Drink plenty of fluids to prevent dehydration, which can be a side effect.
• Drug Interactions: Inform your doctor about all other medicines, supplements, or herbal products you are taking, especially diuretics or insulin/insulin secretagogues.
• Driving: This medicine may cause dizziness or hypoglycemia; avoid driving or operating heavy machinery if you experience these effects.

Storage Store SGLTD S 10/100 MG TABLET in a cool, dry place, away from direct sunlight, and ideally below 30°C. Keep it in its original packaging to protect it from light and moisture, and out of the reach of children and pets.

SGLTD S 10/100 MG TABLET contains Dapagliflozin (10mg) and Sitagliptin (100mg). It is manufactured by Mankind Pharma Ltd..

Here are some frequently asked questions about SGLTD S 10/100 MG TABLET:

What is SGLTD S 10/100 MG TABLET used for?

SGLTD S 10/100 MG TABLET is primarily used to manage Type 2 diabetes mellitus in adults. It helps control high blood sugar levels, especially when diet, exercise, and other medications alone are not sufficient. This medication can also help in reducing the risk of heart attack, heart failure, or other cardiovascular events in diabetic patients. Additionally, it may be used to treat chronic kidney disease in adults with reduced kidney function.

How does SGLTD S 10/100 MG TABLET work?

This tablet is a combination of two antidiabetic medications: Dapagliflozin and Sitagliptin.

• Dapagliflozin (an SGLT2 inhibitor) works by increasing the removal of excess sugar from the body through the urine via the kidneys, thereby lowering blood glucose levels.
• Sitagliptin (a DPP-4 inhibitor) improves insulin levels and lowers glucagon levels (a hormone that raises blood glucose), which decreases the amount of glucose produced by the liver, thus helping to control blood sugar.

What is the usual dosage for SGLTD S 10/100 MG TABLET?

The dosage of SGLTD S 10/100 MG TABLET should be taken as directed by your doctor. It is typically taken orally once daily, with or without food, usually in the morning. It is important to take it at the same time each day to help remember the dose. Do not alter your dosage or stop taking the medicine without consulting your doctor.

What are the possible side effects of SGLTD S 10/100 MG TABLET?

Common side effects may include urinary tract infection, nasal congestion, sore throat, upper respiratory tract infection, headache, dizziness, back pain, joint pain, diarrhea, and nausea. Some individuals may also experience genital yeast infections or increased urination. If you experience severe or worsening symptoms, consult your doctor.

Is SGLTD S 10/100 MG TABLET safe during pregnancy or breastfeeding?

SGLTD S 10/100 MG TABLET is generally not recommended during pregnancy, especially during the second and third trimesters, as limited information is available on its effects and one of its active ingredients (dapagliflozin) is contraindicated. It is also not advised during breastfeeding as it may pass into breast milk and potentially cause adverse effects in infants. Always inform your doctor if you are pregnant, planning to conceive, or breastfeeding before taking this medicine.

Can SGLTD S 10/100 MG TABLET be taken with other medications?

Before taking SGLTD S 10/100 MG TABLET, inform your doctor about all other medicines, supplements, and herbal products you are currently taking to avoid potential drug interactions. It may interact with diuretics (like furosemide, hydrochlorothiazide), insulin, insulin secretagogues (like glipizide, glyburide), and certain antibiotics (like gatifloxacin, clarithromycin). These interactions can increase the risk of side effects like dehydration, low blood pressure, or low blood sugar.

What precautions should be taken while using SGLTD S 10/100 MG TABLET?

It is important to continue with a healthy diet and regular exercise as advised by your doctor. Avoid or limit alcohol consumption, as it can affect blood sugar control and increase the risk of serious side effects like diabetic ketoacidosis. Inform your doctor if you have kidney or liver problems, heart disease, a history of pancreatitis, gallstones, or a urinary tract infection. Monitor your blood sugar levels regularly. If you experience symptoms of low blood sugar (hypoglycemia) such as sweating, dizziness, or a fast heartbeat, consume sugary food or fruit juice immediately.

What happens if a dose of SGLTD S 10/100 MG TABLET is missed?

If you miss a dose, take it as soon as you remember. However, if it's almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

How should SGLTD S 10/100 MG TABLET be stored?

Store SGLTD S 10/100 MG TABLET in a cool, dry place, ideally below 30°C, and away from direct sunlight. Keep it in its original packaging to protect it from light and moisture. Ensure it is kept out of the sight and reach of children.