Susten Sr400 Mg Tablet

SUSTEN SR400 MG TABLET

SUSTEN SR400 MG TABLET, manufactured by SUN PHARMA LABORATORIES LTD., is a sustained-release medication containing a vital female sex hormone.

• Name:

  • Brand Name: SUSTEN SR 400 MG TABLET
  • Common Name: Progesterone (Natural Micronised)

• Composition:

  • Each tablet contains Natural Micronised Progesterone 400 mg.

• Uses: SUSTEN SR400 MG TABLET is prescribed for various gynaecological conditions and to support reproductive health, primarily those stemming from progesterone deficiency or hormonal imbalances.

  • Female Infertility: Used in the management of infertility, including luteal phase support in assisted reproductive technologies (ART) like IVF, by preparing the uterus for pregnancy and increasing the chances of successful conception.
  • Pregnancy Support: Supports the early stages of pregnancy, reduces the risk of threatened abortions, and helps prevent pre-term delivery.
  • Menstrual Disorders: Addresses conditions such as abnormal uterine bleeding, secondary amenorrhea (absence of menstrual periods), irregular menstruation, and painful bleeding due to hormonal imbalance.
  • Hormone Replacement Therapy (HRT): Used in combination with estrogen to alleviate menopausal symptoms and prevent endometrial hyperplasia (thickening of the lining of the uterus), thereby reducing the risk of uterine cancer.
  • Premenstrual Syndrome (PMS): May be used to relieve symptoms of PMS.

• Dosage and Administration:

  • SUSTEN SR400 MG TABLET should be taken orally as prescribed by a healthcare professional.
  • Swallow the tablet whole with a glass of water; do not crush, chew, or break it.
  • It can often be taken with or without food, but if nausea occurs, taking it with food may help. Some sources suggest taking it on an empty stomach.
  • Adhere to the prescribed dose and duration. Taking it at the same time each day helps maintain consistent hormone levels.

• Side Effects:

  • Common Side Effects: Headache, breast pain or tenderness, irregular vaginal bleeding or spotting, stomach or abdominal cramps, bloating, nausea, vomiting, constipation, hair loss, fluid retention (edema), vaginal yeast infection, dizziness, drowsiness, mood swings, tiredness, vaginal discharge, frequent urination, joint pain, and hot flashes. These often subside as the body adjusts.
  • Serious Side Effects (Seek immediate medical attention if experienced): Signs of liver disease (e.g., yellow skin or eyes), severely high blood pressure, migraine-like headaches (occurring for the first time), sudden or gradual partial or complete loss of eyesight, bulging of one or both eyes, double vision, swelling of the optic nerve, retinal vascular lesions, and signs of blood clots (e.g., painful swelling and redness of the legs, sudden chest pain, trouble breathing). Other serious effects can include allergic reactions, swelling, painful urination, depression, memory loss, breast lumps, and dark patches on the skin.

• Precautions:

  • Contraindications: Do not take SUSTEN SR400 MG TABLET if you have a known allergy or hypersensitivity to progesterone or its components, or if you have or have had breast cancer, uterine cancer, unexplained vaginal bleeding, blood clots (thrombosis, DVT, pulmonary embolism), severe liver disease, porphyria, cerebral hemorrhage, or an incomplete abortion.
  • General Warnings:
    • Exercise caution if you have kidney disease, heart problems, high blood pressure, diabetes, asthma, epilepsy, or depression.
    • Consult your doctor if you are pregnant, planning pregnancy (though often prescribed in early pregnancy for support), or breastfeeding.
    • May cause dizziness or drowsiness; avoid driving or operating machinery if affected.
    • Inform your doctor about all other medications, supplements, or herbal products you are currently taking, especially antifungal medicines containing ketoconazole, as interactions may occur.
    • Not recommended for children and adolescents under 18 years of age. Caution is advised with alcohol consumption.

• Storage:

  • Store at controlled room temperature, typically between 20°C to 25°C (68°F to 77°F) or below 30°C.
  • Keep away from moisture, heat, and direct light.
  • Do not freeze.
  • Keep out of reach and sight of children and pets.

SUSTEN SR400 MG TABLET contains progesterone, a female hormone crucial for regulating the menstrual cycle and supporting pregnancy. It is commonly used in various gynecological conditions where there is a deficiency of this hormone.

What is SUSTEN SR400 MG TABLET used for?

SUSTEN SR400 MG TABLET is primarily used to treat female infertility, hormonal imbalances, and related menstrual and pregnancy issues. Specific uses include:

• Hormone Replacement Therapy (HRT): To manage menopausal symptoms and prevent endometrial hyperplasia (thickening of the uterine lining) when given with estrogen.
• Luteal Phase Support: To support the early stages of pregnancy, especially during assisted reproductive technologies like IVF, and to reduce the risk of threatened abortions and preterm delivery.
• Menstrual Disorders: To regulate irregular menstrual cycles, treat amenorrhea (absence of menstrual periods), and manage abnormal uterine bleeding.
• Endometrial Preparation: To prepare the uterus for implantation during fertility treatments.

How does SUSTEN SR400 MG TABLET work?

SUSTEN SR400 MG TABLET contains a synthetic form of progesterone that mimics the natural progesterone produced in the body. It works by replenishing or supplementing the body's progesterone levels. This helps in regulating the menstrual cycle, preparing the uterine lining for a fertilized egg, maintaining early pregnancy by inhibiting uterine contractions, and providing relief from menopause symptoms by balancing hormone levels.

What is the usual dosage of SUSTEN SR400 MG TABLET?

The dosage of SUSTEN SR400 MG TABLET varies based on the condition being treated and individual factors. It should be taken exactly as prescribed by your doctor. It can often be taken with or without food, but taking it at the same time daily is recommended for optimal results. It is important to swallow the tablet whole and not to crush, break, or chew it.

What are the possible side effects of SUSTEN SR400 MG TABLET?

Common side effects may include headache, breast pain or tenderness, irregular vaginal bleeding or spotting, stomach or abdominal cramps, bloating, nausea, vomiting, diarrhea, constipation, dizziness, drowsiness, mood changes, hair loss, fluid retention (edema), and vaginal discharge or yeast infection. Most of these side effects are usually mild and resolve on their own, but if they persist or worsen, you should consult your doctor. Serious side effects, though rare, can include signs of liver disease (like yellow skin or eyes), severely high blood pressure, migraine-like headaches, sudden vision loss, blood clots, or severe allergic reactions.

Is SUSTEN SR400 MG TABLET safe during pregnancy or breastfeeding?

Pregnancy: SUSTEN SR400 MG TABLET is commonly prescribed during early pregnancy, especially in cases of threatened miscarriage or recurrent pregnancy loss due to low progesterone, and is considered safe if prescribed by a doctor. However, it is crucial to consult your doctor before taking it if you are pregnant or planning for pregnancy. Breastfeeding: Components of this medicine may pass into breast milk. It is advisable to consult your doctor if you are breastfeeding, as its effect on breastfed infants is unknown, and the doctor will weigh the benefits and risks.

Can SUSTEN SR400 MG TABLET be taken with other medications?

SUSTEN SR400 MG TABLET can interact with certain medications, potentially reducing its effectiveness or causing undesirable side effects. It's important to inform your doctor about all medicines, supplements, and herbal products you are currently taking. Some medications known to interact include antiepileptics (e.g., carbamazepine, phenytoin), antibiotics (e.g., rifampicin, tetracyclines), anti-HIV medications (e.g., nelfinavir, ritonavir), St. John's Wort, antifungal agents (e.g., ketoconazole), cyclosporine, and blood-thinning medicines (e.g., warfarin).

What precautions should be taken with SUSTEN SR400 MG TABLET?

Before taking SUSTEN SR400 MG TABLET, inform your doctor if you have:

• Allergies to progesterone or soy.
• A history of breast cancer, uterine cancer, or unexplained vaginal bleeding.
• Blood clots or a blood clotting disorder, a history of heart attack or stroke.
• Liver disease.
• Diabetes, high blood pressure, migraine, gallstones, asthma, epilepsy (fits), or a history of depression.
• Kidney disease.
• Drowsiness or dizziness can occur, so caution is advised while driving or operating machinery. Regular medical examinations, including breast and uterine examinations, may be recommended by your doctor during treatment.

What happens if a dose of SUSTEN SR400 MG TABLET is missed?

If you miss a dose of SUSTEN SR400 MG TABLET, take it as soon as you remember. However, if it's almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to compensate for the missed one. It is important not to increase your dosage without consulting your doctor.

How should SUSTEN SR400 MG TABLET be stored?

SUSTEN SR400 MG TABLET should be stored in a cool and dry place, away from direct sunlight, typically between 10ºC to 25ºC or below 30ºC. Keep it in a tightly sealed container, away from moisture, heat, and light, and out of the reach and sight of children and pets. It should not be frozen.