Feburic 80 Mg Tablet (15 Tab)

FEBURIC 80 MG TABLET

FEBURIC 80 MG TABLET, manufactured by AJANTA PHARMA LIMITED, is a medication prescribed for managing elevated uric acid levels.

• Name:

  • Brand Name: Feburic 80 Tablet
  • Common Name: Febuxostat (active ingredient)

• Composition:

  • Each film-coated tablet contains 80 mg of Febuxostat as the active ingredient.
  • Excipients include Lactose monohydrate, Microcrystalline cellulose, Magnesium stearate, Hydroxypropylcellulose, Croscarmellose sodium, and Colloidal silicon dioxide.

• Uses: FEBURIC 80 MG TABLET is primarily used for the following conditions:

  • Treatment and prevention of gout, a type of arthritis caused by the accumulation of uric acid crystals in the joints, leading to pain, swelling, and redness.
  • Chronic hyperuricemia (elevated uric acid levels in the blood), especially when urate deposition has already occurred, such as in gouty arthritis.
  • It is suitable for adult patients who have not responded well to allopurinol or are intolerant to it.
  • May also support patients with chronic kidney disease by managing uric acid levels and help in preventing uric acid kidney stones.

• Dosage and Administration:

  • The recommended oral dose for adults is typically 80 mg once daily.
  • It can be taken with or without food.
  • It is advised to take the medicine at the same time each day to maintain consistent levels in the body.
  • Upon initiation of treatment, there might be a temporary increase in gout symptoms (gout flares) due to changes in serum uric acid levels. Doctors may prescribe additional medications like NSAIDs or colchicine for at least the first six months to help manage these flares.
  • The therapeutic goal is to decrease and maintain serum uric acid levels below 6 mg/dL.

• Side Effects:

  • Common Side Effects: Liver function abnormalities, nausea, joint pain, skin rashes, headache, diarrhea, dizziness, and localized swelling (edema).
  • Serious Side Effects: Include heart problems (such as an increased risk of heart attack or stroke), severe skin reactions (like Stevens-Johnson Syndrome), serious allergic/hypersensitivity reactions, and liver problems. Patients should seek immediate medical attention if they experience symptoms of liver disease (persistent nausea, dark urine, yellowing of eyes or skin) or severe allergic reactions.

• Precautions:

  • Patients with pre-existing major cardiovascular diseases (e.g., myocardial infarction, stroke, or unstable angina) should use Feburic with caution due to observed higher numbers of fatal cardiovascular events in some studies compared to allopurinol.
  • Caution is advised for patients with kidney or liver problems. Regular blood tests may be required to monitor liver function.
  • Not recommended for use in children under 18 years of age, or in pregnant or breastfeeding women.
  • Patients with a history of allergies to febuxostat or any of its components should avoid this medicine.
  • Inform your doctor about all current medications as Feburic may interact with drugs like azathioprine, mercaptopurine, and theophylline.
  • Caution is required in patients with thyroid disorders or Lesch-Nyhan syndrome.

• Storage:

  • Store below 30°C.
  • Keep in a cool and dry place, away from direct sunlight.
  • Keep out of sight and reach of children.

FEBURIC 80 MG TABLET contains Febuxostat and is primarily used for the long-term management of chronic hyperuricemia (high uric acid levels in the blood) in adults who have gout. Gout is a type of arthritis caused by the accumulation of uric acid crystals in the joints, leading to pain, swelling, and stiffness.

What is FEBURIC 80 MG TABLET used for?

FEBURIC 80 MG TABLET is prescribed for the treatment of chronic hyperuricemia in adult patients with gout, including those with a history or presence of tophi (uric acid deposits) and/or gouty arthritis. It is often used for individuals who have not responded adequately to other treatments, such as allopurinol, or who cannot tolerate them.

How does FEBURIC 80 MG TABLET work?

FEBURIC 80 MG TABLET contains febuxostat, which belongs to a class of medicines called xanthine oxidase inhibitors. It works by blocking the enzyme xanthine oxidase, an enzyme in the body responsible for converting purines into uric acid. By inhibiting this enzyme, febuxostat reduces the production of uric acid, thereby lowering its levels in the blood. This helps prevent the formation of uric acid crystals in the joints and tissues, which in turn reduces gout symptoms like pain and inflammation.

What is the usual dosage for FEBURIC 80 MG TABLET?

The recommended oral dose for FEBURIC 80 MG TABLET in adults is 80 mg once daily, taken with or without food. It is important to take the medicine at the same time each day to help with adherence. Your doctor may initially prescribe a lower dose and adjust it based on your serum uric acid levels, aiming to maintain levels below 6 mg/dL.

What are the possible side effects of FEBURIC 80 MG TABLET?

Common side effects may include headache, nausea, diarrhea, skin rashes, abnormal liver function, and muscle pain. Some patients may experience an increase in gout attacks (flares) during the initial months of treatment as uric acid levels change and crystals mobilize from tissues. Your doctor may prescribe additional medications to manage these initial flares. More serious but rare side effects can include heart problems, severe allergic reactions (such as Stevens-Johnson Syndrome), and significant liver problems.

Is FEBURIC 80 MG TABLET safe during pregnancy or breastfeeding?

FEBURIC 80 MG TABLET is generally not recommended for use during pregnancy unless your doctor determines it is absolutely necessary, and only after a thorough evaluation of the potential benefits versus risks. It is not known whether febuxostat is excreted in human breast milk, but animal studies have indicated its presence in breast milk and impaired development in suckling offspring. Therefore, FEBURIC 80 MG TABLET should not be used while breastfeeding.

Can FEBURIC 80 MG TABLET be taken with other medications?

It is crucial to inform your doctor about all prescription and non-prescription medications, vitamins, and herbal supplements you are taking to avoid potential drug interactions. FEBURIC 80 MG TABLET should not be taken with certain immunosuppressants like mercaptopurine and azathioprine, as it can lead to a significant increase in their levels and severe toxicity. Caution is also advised when taking it with theophylline.

What precautions should be taken while using FEBURIC 80 MG TABLET?

• Gout Flares: You might experience an increase in gout flares when starting treatment. Do not discontinue the medicine; your doctor may prescribe other medications to manage these flares.
• Cardiovascular Health: If you have a history of major cardiovascular diseases (e.g., heart attack, stroke), your doctor will carefully consider the risks and benefits, as some studies have shown a higher number of fatal cardiovascular events with febuxostat compared to allopurinol in such patients.
• Liver and Kidney Issues: Use with caution if you have severe liver or kidney problems. Your doctor may recommend regular monitoring of your liver and kidney function.
• Allergic Reactions: Be vigilant for signs of severe allergic reactions, such as skin rash, itching, swelling of the face or throat, or difficulty breathing, and seek immediate medical attention if they occur.
• Children: This medicine is not recommended for individuals under 18 years of age.
• Driving and Operating Machinery: Since FEBURIC 80 MG TABLET may cause dizziness, drowsiness, or blurred vision, avoid driving or operating heavy machinery until you understand how the medication affects you.
• Alcohol Consumption: Exercise caution with alcohol consumption, as it can increase uric acid levels and potentially reduce the effectiveness of the treatment.

What happens if a dose of FEBURIC 80 MG TABLET is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to compensate for the missed one.

How should FEBURIC 80 MG TABLET be stored?

FEBURIC 80 MG TABLET should be stored in a cool, dry place, away from direct sunlight and moisture. It is generally recommended to store it at room temperature, typically below 30°C (between 15°C and 30°C), and out of the reach of children.