Euclide 80 Mg (10 Tablet)

EUCLIDE 80 MG (10 TABLET) by ALKEM LABORATORIES LTD

Euclide 80 mg Tablet is an oral anti-diabetic medication used to manage type 2 diabetes mellitus in adults. It is manufactured by Alkem Laboratories Ltd..

• Composition

  • Active Ingredient: Gliclazide 80 mg.

• Uses Euclide 80 mg Tablet is primarily used for the management of type 2 diabetes mellitus when diet, exercise, and weight loss alone are insufficient to control blood sugar levels. Gliclazide, the active ingredient, works by stimulating the beta-cells in the pancreas to secrete more insulin and by enhancing the body's sensitivity to insulin. It also helps in maintaining optimal blood sugar levels by reducing glucose production in the liver.

• Dosage and Administration Euclide 80 mg Tablet is for oral administration. The total daily dose can range from 40 mg to 320 mg, adjusted according to the individual patient's response. It is typically commenced with 40-80 mg daily. A single dose should not exceed 160 mg. When higher doses are required (more than 160 mg), the tablets should be taken twice daily with the main meals. It is recommended to take this medicine with food, ideally in the morning with breakfast, to reduce the risk of low blood sugar. Do not chew, crush, or break the tablet.

• Side Effects Common side effects of Euclide 80 mg Tablet include:

  • Hypoglycaemia (low blood sugar), which may present as weakness, shaking, sweating, confusion, dizziness, headache, or intense hunger.
  • Gastrointestinal disturbances such as abdominal pain, nausea, vomiting, diarrhoea, or constipation.
  • Headache and dizziness.
  • Asthenia (feeling weak or lacking energy).
  • Skin rash or itching.

  Serious side effects, though less common, require immediate medical attention. These can include severe skin reactions (peeling and blistering), seizures, or unconsciousness.

• Precautions

  • Contraindications: Euclide 80 mg Tablet is contraindicated in patients with known hypersensitivity to gliclazide, other sulfonylureas, or related drugs. It should not be used in cases of type 1 diabetes mellitus, diabetic ketoacidosis, severe renal or hepatic impairment, porphyria, or during pregnancy and breastfeeding.
  • Alcohol: Exercise caution or avoid alcohol consumption, as it can potentiate the blood sugar-lowering effect and increase the risk of hypoglycemia.
  • Hypoglycemia: Patients should be aware of the symptoms of hypoglycemia and always carry a fast-acting carbohydrate (like candy or juice) to manage blood sugar drops. Skipping meals can affect blood sugar levels.
  • Renal/Hepatic Impairment: Caution is advised in patients with mild to moderate liver or kidney impairment, and it is not recommended in severe cases.
  • Drug Interactions: Inform your doctor about all medicines, supplements, or herbal products being taken. Interactions may occur with other antidiabetic medications, corticosteroids, oral contraceptives, miconazole, and phenylbutazone, among others.
  • Driving and Operating Machinery: Hypoglycemia may affect the ability to drive or operate machinery, so caution is advised.

• Storage Store Euclide 80 mg Tablet below 30°C (or below 25°C), in a cool, dry place, protected from light. Keep out of the reach of children.

What is EUCLIDE 80 MG used for?

EUCLIDE 80 MG, which contains Gliclazide, is an anti-diabetic medication used to treat adults with type 2 diabetes mellitus. It helps control high blood sugar levels when diet, exercise, and weight loss alone are insufficient. It is not suitable for treating type 1 diabetes.

How does EUCLIDE 80 MG work?

EUCLIDE 80 MG works by stimulating the beta-cells in your pancreas to release more insulin. Insulin is a hormone that helps your body's cells absorb glucose from the blood for energy. Additionally, it may enhance the body's sensitivity to insulin, leading to better glucose absorption and lower blood sugar levels.

What is the usual dosage for EUCLIDE 80 MG?

The dosage of EUCLIDE 80 MG is determined by your doctor and can range from 40 mg to 320 mg daily. If a daily dose exceeds 160 mg, it is typically divided into two equal parts. It is usually taken once daily, with or after a meal, often with breakfast. You should always follow your doctor's instructions and not modify the dose without consulting them.

What are the possible side effects of EUCLIDE 80 MG?

Common side effects include low blood sugar (hypoglycemia), which can manifest as sweating, shakiness, and weakness. Other common side effects may include headaches, dizziness, nausea, vomiting, stomach upset, constipation, and occasional weight gain. If you experience severe side effects like severe allergic reactions or severe hypoglycemia (leading to confusion or fainting), seek immediate medical attention.

Is EUCLIDE 80 MG safe during pregnancy or breastfeeding?

EUCLIDE 80 MG is not recommended for use during pregnancy or while breastfeeding. There is limited or no safety data available regarding its use in pregnant women, and it is unknown if gliclazide passes into human milk. If you are pregnant, planning a pregnancy, or breastfeeding, consult your doctor for alternative diabetes management options.

Can EUCLIDE 80 MG be taken with other medications?

EUCLIDE 80 MG can interact with several other medications. Its blood sugar-lowering effect may be enhanced by other antidiabetic medications, certain antibiotics (like miconazole, chloramphenicol, sulfonamides, tetracyclines), blood thinners, ACE inhibitors (e.g., captopril, enalapril), MAOIs, cimetidine, and ranitidine. Conversely, medications such as corticosteroids, oral contraceptives, diazoxide, beta-blockers, rifamycins, and chlorpromazine may reduce its effectiveness or mask symptoms of low blood sugar. It should not be used with miconazole or phenylbutazone. Always inform your doctor about all prescription and non-prescription medications, supplements, and herbal products you are taking to avoid potential interactions.

What precautions should be taken while taking EUCLIDE 80 MG?

Several precautions should be observed when taking EUCLIDE 80 MG. It is crucial to monitor your blood sugar levels regularly and always carry a sugary snack or juice to treat unexpected low blood sugar. Avoid consuming alcohol, as it can interfere with blood glucose levels and increase the risk of hypoglycemia. Exercise caution when driving or operating machinery, as low blood sugar can impair your ability. Inform your doctor if you have kidney or liver problems, thyroid disorders, a hereditary condition called glucose-6-phosphate dehydrogenase (G6PD) deficiency, or are at risk of developing low blood sugar. Do not stop taking the medicine without consulting your doctor. This medicine is not recommended for children or individuals with type 1 diabetes.

What happens if a dose of EUCLIDE 80 MG is missed?

If you miss a dose of EUCLIDE 80 MG, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

How should EUCLIDE 80 MG be stored?

EUCLIDE 80 MG should be stored in a cool, dry place, protected from direct light, and out of the sight and reach of children. The ideal storage temperature is typically below 30°C.