Pregacip M Capsule (10 Cap)

PREGACIP M CAPSULE (10 CAP) by CIPLA LTD.(GENERIC DIVISION)

PREGACIP M CAPSULE is a prescription medication combining two active ingredients to manage nerve-related pain and support nerve health.

• Name:

  • Brand Name: PREGACIP M CAPSULE
  • Common Name: Pregabalin and Methylcobalamin Capsules

• Composition:

  • Each capsule typically contains:
    • Pregabalin: 75 mg
    • Methylcobalamin: 750 mcg

• Uses: PREGACIP M CAPSULE is primarily used for the treatment of neuropathic pain, which is pain caused by nerve damage. This includes conditions such as:

  • Diabetic neuropathy
  • Post-herpetic neuralgia (nerve pain after shingles)
  • Fibromyalgia-related pain
  • Pain associated with spinal cord injuries
  • Peripheral neuropathy It may also contribute to anxiety relief, general pain management, improved sleep quality, and mood stabilization. Pregabalin also possesses anticonvulsant activity.

• Dosage and Administration: The typical recommended dosage is one capsule twice a day, taken orally with water. It can be taken with or without food, but consistency in daily intake is important to maintain stable medication levels. Do not crush, chew, or break the capsule. It is crucial to follow the doctor's prescribed dose and duration and not to stop the medication abruptly without consulting a doctor, as this can lead to withdrawal symptoms.

• Side Effects:

  • Common Side Effects: Dizziness, drowsiness, fatigue, blurred vision, headache, dry mouth, nausea, vomiting, diarrhea, increased appetite, weight gain, uncoordinated body movements, hot sensation, and sweating.
  • Serious Side Effects: Report immediately if you experience allergic reactions (e.g., itching, rash, difficulty breathing, swelling of the face, lips, tongue, or neck), unusual mood changes, new or worsening depression, suicidal thoughts or behavior, signs of heart failure, kidney problems (decreased urination), or oedema (swelling of limbs). Convulsions may occur if the medicine is stopped suddenly.

• Precautions:

  • Avoid driving or operating heavy machinery until you understand how the medication affects you, as it can cause dizziness and drowsiness.
  • Alcohol consumption should be avoided as it can increase the risk of dizziness and drowsiness.
  • Inform your doctor about all existing medical conditions, especially kidney disease, liver problems, heart disease (including heart failure), and diabetes.
  • Patients with diabetes who experience weight gain may require adjustments in their diabetic medication.
  • Not recommended for individuals below 18 years of age.
  • Pregnant or breastfeeding women should consult their doctor before use, as it may be unsafe during pregnancy and breastfeeding is generally not recommended.
  • The medication can be habit-forming, so follow prescribed dosage and duration.
  • Do not discontinue treatment without medical advice to prevent withdrawal symptoms and potential worsening of the condition.

• Storage: Store PREGACIP M CAPSULE in a cool, dry place, typically below 30°C. Protect it from direct sunlight and moisture. Keep the medication out of reach of children and pets.

What is PREGACIP M CAPSULE used for?

PREGACIP M CAPSULE is primarily used to treat neuropathic pain, which is pain caused by nerve damage. This can include conditions such as diabetic neuropathy (nerve pain due to diabetes), postherpetic neuralgia (nerve pain after shingles), peripheral neuropathy, and nerve pain associated with spinal cord injury. It may also be used to help manage fibromyalgia, restless legs syndrome, anxiety, and to improve sleep quality in some individuals.

How does PREGACIP M CAPSULE work?

PREGACIP M CAPSULE is a combination of two active ingredients: Pregabalin and Methylcobalamin. Pregabalin works by decreasing the pain signals sent by damaged nerves in the body, primarily by modulating calcium channel activity in nerve cells. Methylcobalamin, a form of Vitamin B12, helps in the formation of new nerve cells, rejuvenates damaged nerve cells, and aids in nerve regeneration by producing myelin, which is the protective layer around nerve fibers.

What is the usual dosage for PREGACIP M CAPSULE?

The dosage of PREGACIP M CAPSULE is determined by your doctor based on your medical condition, age, body weight, and kidney function. For neuropathic pain, an initial dose of Pregabalin, for example, might be 75 mg two times a day (150 mg/day), which can be increased based on efficacy and tolerability, typically up to 300 mg/day, and in some cases, up to 450 mg/day (with a maximum of 600 mg/day). Methylcobalamin dosages commonly range from 0.5 mg to 1.5 mg per day orally, or 750 mcg to 1500 mcg in combination capsules. This medicine is often prescribed as one capsule twice daily. Always follow your doctor's instructions regarding dosage and duration of treatment.

What are the possible side effects of PREGACIP M CAPSULE?

Common side effects may include dizziness, drowsiness, headache, dry mouth, nausea, vomiting, diarrhea, increased appetite, weight gain, blurred vision, and uncoordinated body movements. Some individuals may also experience fatigue, stomach pain, or irritability. Rarely, more serious side effects can occur, such as allergic reactions (swelling of the face, lips, tongue, difficulty breathing, hives), suicidal thoughts, swelling of the limbs, or heart problems. If you experience any severe or persistent side effects, or any signs of an allergic reaction, you should contact your doctor immediately.

Is PREGACIP M CAPSULE safe during pregnancy or breastfeeding?

PREGACIP M CAPSULE is generally not recommended during pregnancy unless specifically advised by a doctor, and only if the potential benefits are considered to outweigh the risks. The safety and efficacy during pregnancy have not been fully evaluated, and animal studies have shown reproductive toxicity. Women of childbearing potential should use effective contraception while taking this medication. During breastfeeding, PREGACIP M CAPSULE should be used with caution and only if your doctor deems it necessary. It is unknown if Pregabalin is excreted in human breast milk, though it has been found in rat milk.

Can PREGACIP M CAPSULE be taken with other medications?

PREGACIP M CAPSULE may interact with certain other medications. It's important to inform your doctor about all prescription, over-the-counter, and herbal medicines you are taking. Caution is advised when taken with painkillers (e.g., oxycodone), opioids, anti-anxiety drugs (e.g., lorazepam), antacids (e.g., omeprazole), certain antibiotics (e.g., neomycin), anti-gout medication (e.g., colchicine), and other central nervous system (CNS) depressants, as these combinations can increase the risk of side effects like dizziness, drowsiness, respiratory failure, or coma.

What precautions should be taken while taking PREGACIP M CAPSULE?

It is important to avoid alcohol consumption while taking PREGACIP M CAPSULE as it can worsen side effects like dizziness and drowsiness. Due to the potential for dizziness and sleepiness, you should avoid driving or operating heavy machinery until you know how the medication affects you. Inform your doctor if you have kidney or liver disease, heart problems (as it may increase the risk of heart failure), diabetes (as weight gain might necessitate changes in diabetic medicines), a history of alcoholism, drug abuse, or suicidal thoughts. Do not stop taking the medication suddenly, as this can lead to withdrawal symptoms such as anxiety, sleeping difficulties, nausea, pain, and sweating; instead, the dosage should be gradually reduced under medical supervision.

What happens if a dose of PREGACIP M CAPSULE is missed?

If you miss a dose of PREGACIP M CAPSULE, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one, as this can increase the risk of side effects.

How should PREGACIP M CAPSULE be stored?

PREGACIP M CAPSULE should be stored in a cool and dry place, away from direct sunlight, and at temperatures not exceeding 30°C. Keep the medicine out of the sight and reach of children and pets.