Caberlin 0.5 Mg Tablet (4 Tab)

Name

• Common Name: Caberlin 0.5 mg Tablet
• Brand Name: Caberlin
• Manufacturer: SUN PHARMA LABORATORIES LTD.

Composition

• Active Ingredient: Cabergoline 0.5 mg
• Inactive Ingredients: Anhydrous lactose, leucine

Uses Caberlin 0.5 mg Tablet is primarily prescribed for the treatment of hyperprolactinemia, a condition characterized by abnormally high levels of the hormone prolactin in the body. This condition can lead to symptoms such as irregular menstruation, infertility, and unwanted breast milk production (galactorrhea). It is also used to suppress or stop breast milk production after childbirth, miscarriage, abortion, or stillbirth when breastfeeding is not desired. Additionally, it aids in managing prolactinomas, which are pituitary tumors that secrete excess prolactin.

Dosage and Administration The typical starting dosage is 0.25 mg taken orally twice weekly. The dosage may be gradually increased by 0.25 mg twice weekly at intervals of no less than 4 weeks to achieve normal serum prolactin levels. The maximum recommended dosage is 1 mg orally twice weekly. Caberlin 0.5 mg Tablet can be administered with or without food.

Side Effects Common side effects include nausea, vomiting, indigestion, constipation, headache, dizziness, fatigue, and breast pain. More serious, though less frequent, side effects can include severe dizziness, difficulty breathing, blurred vision, swelling of ankles or feet, and potential cardiac valvulopathy or fibrosis (scarring of organ tissues) with long-term, high-dose use.

Precautions

• Contraindications: Caberlin 0.5 mg Tablet is not recommended for individuals with uncontrolled hypertension, known hypersensitivity to cabergoline or other ergot derivatives, or pre-existing heart valve conditions.
• Special Populations: It should be avoided during pregnancy unless absolutely necessary due to definite evidence of risk to the developing baby. Breastfeeding mothers should not use this medicine as it suppresses lactation. Use with caution in patients with liver, kidney, or heart problems. Not recommended for females under 16 years of age.
• Interactions: Alcohol consumption should be avoided as it may worsen side effects such as dizziness and drowsiness. Inform your doctor about all other medications, especially antipsychotics (e.g., chlorpromazine, haloperidol, risperidone), anti-nausea medications (e.g., metoclopramide), and certain antibiotics (e.g., erythromycin), as they can interact with Caberlin.
• Activities: This medicine may cause dizziness and drowsiness, therefore caution is advised when driving or operating machinery.

Storage Store Caberlin 0.5 mg Tablet at room temperature, ideally between 20°C and 25°C (68°F and 77°F) or below 30°C. Keep it in the original container, away from direct sunlight, moisture, and out of reach of children.

Here are frequently asked questions and answers about CABERLIN 0.5 MG TABLET (4 TAB) by SUN PHARMA LABORATORIES LTD.

What is Caberlin 0.5 MG Tablet used for?

Caberlin 0.5 MG Tablet, containing cabergoline, is primarily used to treat hyperprolactinemia, a condition where there are abnormally high levels of the hormone prolactin in the body. High prolactin levels can lead to various issues, including irregular menstrual cycles, infertility, abnormal breast milk production (galactorrhea) in women, and sexual dysfunction in men, such as decreased libido and erectile difficulties. It is also used to suppress or stop breast milk production after childbirth, stillbirth, abortion, or miscarriage when breastfeeding is not desired. In some cases, higher doses may be used as a second-line treatment for Parkinson's disease or acromegaly.

How does Caberlin 0.5 MG Tablet work?

Caberlin 0.5 MG Tablet is a dopamine agonist. It works by mimicking the action of dopamine, a chemical in the brain, by binding to and stimulating dopamine D2 receptors, particularly in the pituitary gland. This action directly inhibits the secretion of prolactin from the pituitary gland, thereby reducing elevated prolactin levels in the blood.

What is the usual dosage for Caberlin 0.5 MG Tablet?

For hyperprolactinemia, the typical starting dosage is 0.25 mg taken twice per week (e.g., Monday and Thursday). Your doctor may gradually increase the dosage by 0.25 mg per week at monthly intervals, based on your prolactin levels and response, up to a maximum of 1 mg twice per week. To stop lactation immediately after childbirth, a single dose of 1 mg (two 0.5 mg tablets) is often given on the first day. For suppressing established lactation, the recommended dose is typically 0.25 mg every 12 hours for two days, for a total dose of 1 mg. It can be taken with or without food, but taking it with food may help reduce stomach upset.

What are the possible side effects of Caberlin 0.5 MG Tablet?

Common side effects can include nausea, constipation, headache, dizziness, weakness, fatigue, stomach pain, heartburn, and drowsiness. Some individuals may also experience low blood pressure, especially when getting up from a sitting or lying position. More serious, but rare, side effects include scarring of tissues in organs (fibrosis), particularly affecting heart valves, lungs, or the abdomen. Symptoms of these serious effects can include trouble breathing, shortness of breath, persistent cough, chest pain, swelling in the legs, ankles, or feet, and changes in heart rhythm. Psychiatric symptoms such as depression, anxiety, or, rarely, hallucinations have also been reported.

Is Caberlin 0.5 MG Tablet safe during pregnancy or breastfeeding?

During pregnancy: Caberlin (cabergoline) is considered a Pregnancy Category B drug. Animal studies have not shown a risk to the fetus, but there are not enough well-controlled studies in pregnant humans. It should only be used during pregnancy if clearly needed, and women should use effective contraception and inform their doctor immediately if they become pregnant while taking this medication.

During breastfeeding: Caberlin is generally not recommended during breastfeeding because it works by suppressing milk production. It is not known if the drug passes into breast milk, and if it does, it could cause side effects in the breastfed child.

Can Caberlin 0.5 MG Tablet be taken with other medications?

Caberlin can interact with other medications. It should not be taken with dopamine antagonists, such as certain antipsychotic drugs (e.g., haloperidol, chlorpromazine) or anti-nausea medications (e.g., metoclopramide, promethazine), as these can counteract the effects of cabergoline. Caution is also advised with other ergot derivatives. Certain antibiotics, including erythromycin, clarithromycin, and azithromycin, may increase the levels of cabergoline in the blood, potentially increasing the risk of side effects. It is crucial to inform your doctor about all medications, vitamins, and herbal supplements you are currently taking to avoid potential drug interactions. Alcohol consumption should be avoided or restricted, as it may enhance dizziness and drowsiness caused by the medication.

What precautions should be taken while using Caberlin 0.5 MG Tablet?

Before starting Caberlin, inform your doctor if you have uncontrolled high blood pressure, heart valve problems, or a history of tissue scarring (fibrosis) affecting your lungs, heart, or abdomen, as this medication can worsen these conditions. Your doctor may perform cardiovascular evaluations, including an echocardiogram, before and during treatment, especially for long-term use, to monitor for heart valve issues. Use caution if you have liver problems, as Caberlin is metabolized by the liver, and impairment can lead to drug accumulation and increased side effects. This medicine can cause dizziness or drowsiness, so you should avoid driving or operating heavy machinery until you know how it affects you. To prevent lightheadedness, rise slowly when standing up from a sitting or lying position. Women of childbearing potential should use effective contraception during treatment.

What happens if a dose of Caberlin 0.5 MG Tablet is missed?

If you miss a dose of Caberlin 0.5 MG Tablet, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to compensate for a missed one, as this can increase the risk of side effects. If more than two days have passed since the missed dose, it's generally advised to skip it and resume your next scheduled dose.

How should Caberlin 0.5 MG Tablet be stored?

Caberlin 0.5 MG Tablet should be stored at room temperature, typically between 20°C and 25°C (68°F and 77°F). Keep the medication in its original container, protected from heat, moisture, and direct light. Avoid storing it in moist or damp areas, such as bathrooms. Always keep it out of the reach of children.