Apixator 2.5 Tablet (10 Tab)

Apixator 2.5 Tablet

Apixator 2.5 Tablet, manufactured by Torrent Pharmaceuticals Ltd, is an anticoagulant medication commonly referred to as a blood thinner. It works by preventing the formation of blood clots in the body.

• Name:
  • Brand Name: Apixator 2.5 Tablet
  • Common Name: Apixaban
• Composition:
  • Apixator 2.5 Tablet contains Apixaban at a strength of 2.5 mg per tablet. Apixaban is a direct oral anticoagulant (DOAC) that works by inhibiting Factor Xa, a crucial enzyme in the blood clotting process. By blocking Factor Xa, it reduces thrombin generation and the development of blood clots.
• Uses: Apixator 2.5 Tablet is primarily used for the prevention and treatment of blood clots in adults. Specific uses include:
  • Prevention of stroke and systemic embolism in patients with non-valvular atrial fibrillation (irregular heartbeat).
  • Treatment and prevention of deep vein thrombosis (DVT), which are blood clots in the legs.
  • Treatment and prevention of pulmonary embolism (PE), which are blood clots in the lungs.
  • Prevention of venous thromboembolism (VTE) in patients undergoing elective hip or knee replacement surgery.
• Dosage and Administration:
  • Apixator 2.5 Tablet should be taken orally as directed by your doctor.
  • The tablet should be swallowed whole with a glass of water, with or without food.
  • Avoid chewing, crushing, or breaking the tablet.
  • It is typically taken twice daily, ideally at the same time each day, for optimal results.
  • Do not stop taking the medicine without consulting your doctor, as this may increase the risk of blood clots.
• Side Effects: Common side effects may include:
  • Bleeding (e.g., nosebleeds, bruising, bleeding in the eyes, stomach, nose, gums, urine, rectum, or bowel).
  • Nausea.
  • Anemia (reduction in red blood cells, leading to tiredness and weakness).
  • Bruising and swelling.
  • Low blood pressure, which may cause faintness or a quickened heartbeat. Serious side effects, such as excessive or severe bleeding, black or tarry stools, or coughing up or vomiting blood, require immediate medical attention.
• Precautions:
  • Inform your doctor about any pre-existing medical conditions, especially bleeding disorders, liver or kidney problems, or a history of stomach ulcers, recent bleeding in the brain, or high blood pressure.
  • Caution is advised during pregnancy and breastfeeding; consult your doctor before taking Apixator 2.5 Tablet.
  • Alcohol consumption may increase the risk of bleeding.
  • Inform your doctor or healthcare provider if you are scheduled for surgery or dental treatment, as temporary discontinuation of the medicine may be necessary.
  • Interactions can occur with other medicines, including antiplatelet agents (e.g., clopidogrel), NSAIDs (e.g., ibuprofen, naproxen), and certain antifungal medications (e.g., ketoconazole).
  • Apixator 2.5 Tablet is not recommended for children and adolescents under 18 years of age.
  • Caution is advised for elderly patients over 75 years of age.
• Storage:
  • Keep Apixator 2.5 Tablet at room temperature, ideally below 30°C.
  • Store it away from direct sunlight and moisture.
  • Always keep the tablet in its original packaging until it is time to take it.
  • Keep it out of reach of children.
  • Remember to use this medicine before its expiry date.

What is Apixator 2.5 Tablet used for?

Apixator 2.5 Tablet is an anticoagulant, commonly known as a blood thinner, used to prevent and treat blood clots. It helps to prevent and treat clot formation in the veins of your legs (deep vein thrombosis), lungs (pulmonary embolism), brain, and heart. It is also prescribed to reduce the risk of stroke and systemic embolism in individuals with non-valvular atrial fibrillation (irregular heartbeat) and to prevent blood clots in patients who have undergone elective hip or knee replacement surgeries.

How does Apixator 2.5 Tablet work?

Apixator 2.5 Tablet contains apixaban, a direct oral anticoagulant (DOAC) that works by selectively and reversibly blocking a crucial blood clotting factor called Factor Xa. By inhibiting Factor Xa, apixaban effectively reduces the generation of thrombin and the overall development of blood clots in the body.

What is the usual dosage for Apixator 2.5 Tablet?

Apixator 2.5 Tablet should be taken exactly as prescribed by your doctor, typically twice daily. It can be taken with or without food, but it is best to take it at a fixed time each day to maintain consistent levels in your body. Swallow the tablet whole with a glass of water; avoid chewing, crushing, or breaking it. If you have difficulty swallowing, the tablet may be crushed and mixed with water, apple juice, or apple puree immediately before consumption.

What are the possible side effects of Apixator 2.5 Tablet?

The most common side effect of Apixator 2.5 Tablet is an increased tendency to bleed, which can manifest as nosebleeds, bruising, blood in the urine or stool, or bleeding in the eyes, stomach, or gums. Other common side effects include anemia (which may cause tiredness or paleness), nausea, low blood pressure (potentially leading to fainting or a quickened heartbeat), and swelling. In rare cases, severe allergic reactions causing swelling of the lips, mouth, tongue, and throat, along with breathing difficulties, may occur and require immediate medical attention.

Is Apixator 2.5 Tablet safe during pregnancy or breastfeeding?

Apixator 2.5 Tablet is generally considered unsafe for use during pregnancy. Animal studies have shown harmful effects on the developing baby, and its use may increase the risk of bleeding during pregnancy and delivery. For breastfeeding mothers, Apixator 2.5 Tablet is also probably unsafe, as limited human data suggest the drug may pass into breast milk and potentially harm the baby. Always consult your doctor if you are pregnant, planning a pregnancy, or breastfeeding.

Can Apixator 2.5 Tablet be taken with other medications?

Combining Apixator 2.5 Tablet with other blood thinners (such as warfarin, rivaroxaban, heparin, or antiplatelet agents like clopidogrel and ticagrelor) can significantly increase the risk of bleeding and is generally contraindicated or requires extreme caution. Non-steroidal anti-inflammatory drugs (NSAIDs) like ibuprofen can also increase bleeding risk. Certain antifungal medications (e.g., ketoconazole, itraconazole) may enhance Apixator's effects, while some epilepsy medications (e.g., carbamazepine, phenytoin) and the herbal supplement St. John's Wort can decrease its effectiveness. Always inform your doctor about all prescription, over-the-counter, and herbal medications you are taking to avoid potential interactions.

What precautions should be taken while on Apixator 2.5 Tablet?

You should inform your doctor if you have any pre-existing medical conditions, particularly kidney or liver problems, high blood pressure, or bleeding disorders. Due to the increased risk of bleeding, be cautious with activities that could cause injury, such as shaving, cutting nails, or engaging in contact sports. It is crucial not to stop taking Apixator 2.5 Tablet without your doctor's guidance, as abrupt discontinuation can quickly increase your risk of a heart attack, stroke, or blood clot formation. If you are scheduled for any surgery or dental procedure, inform your healthcare provider that you are taking this medication, as it may need to be temporarily stopped. Avoid excessive alcohol consumption, as it can further increase the risk of bleeding.

What happens if a dose of Apixator 2.5 Tablet is missed?

If you miss a dose of Apixator 2.5 Tablet, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

How should Apixator 2.5 Tablet be stored?

Store Apixator 2.5 Tablet at room temperature, ideally below 30°C. Keep the medicine in its original packaging, away from direct sunlight and moisture. Ensure it is kept out of the reach of children and pets. Do not use the medicine beyond its expiry date.