Amlosafe Tm 80 Mg Tablet (10 Tab)

AMLOSAFE TM 80 MG TABLET

Name: Amlosafe TM 80 Tablet (Brand Name)

Composition: Each tablet contains Amlodipine (5 mg) and Telmisartan (80 mg).

Uses: AMLOSAFE TM 80 MG TABLET is a combination medication primarily used for the management of high blood pressure (hypertension). It is often prescribed when a single blood pressure medicine does not adequately control blood pressure. This medicine also helps in reducing the risk of cardiovascular events such as heart attacks and strokes. It can also be used to manage chronic stable angina, vasospastic angina, and coronary artery disease.

Dosage and Administration: This medicine should be taken orally as a whole tablet with a glass of water, and should not be crushed or chewed. It can be taken with or without food, preferably at a fixed time each day, as prescribed by your doctor. The dosage is determined by your doctor based on your condition and response to the medicine. It is crucial to adhere to the prescribed dosage and duration for optimal results.

Side Effects: Common side effects include headache, dizziness, nausea, back pain, fatigue, peripheral oedema (swelling in limbs), flushing, and palpitations. More serious, though less common, side effects can include a severe decrease in blood pressure, swelling of body parts, unexplained weight gain, chest pain, and high blood potassium levels. Consult your doctor if any side effects persist or worsen.

Precautions:

• Pregnancy & Breastfeeding: AMLOSAFE TM 80 MG TABLET is generally not recommended during pregnancy due to potential risks to the developing baby. It is also not recommended during breastfeeding.
• Alcohol: Avoid alcohol consumption as it may increase the risk of dizziness and further lower blood pressure.
• Medical Conditions: Caution is advised for patients with liver disease, kidney disease, diabetes, heart conditions (like severe congestive heart failure), or those on a low-sodium diet. Regular monitoring of blood pressure and kidney function is necessary.
• Drug Interactions: Inform your doctor about all ongoing medications, as it can interact with potassium-sparing diuretics, NSAIDs, statins (e.g., simvastatin), digoxin, aliskiren, and certain antifungal medicines or antibiotics.
• Driving: This medicine may cause dizziness or sleepiness, so avoid driving or operating machinery until you know how it affects you.

Storage: Store below 30°C in a cool and dry place, away from direct sunlight. Keep out of sight and reach of children.

AMLOSAFE TM 80 MG Tablet, manufactured by Aristo Pharmaceuticals Private Limited, is a combination medication containing Amlodipine (5 mg) and Telmisartan (80 mg). It is primarily used for the management of high blood pressure.

What is AMLOSAFE TM 80 MG Tablet used for?

AMLOSAFE TM 80 MG Tablet is primarily used to treat high blood pressure (hypertension). It is often prescribed when a single blood pressure medication is not sufficient to control blood pressure effectively. Additionally, it can help manage conditions like chronic stable angina, vasospastic angina, and coronary artery disease, thereby reducing the risk of heart attack, stroke, and kidney problems associated with high blood pressure.

How does AMLOSAFE TM 80 MG Tablet work?

This medicine works through a dual mechanism due to its two active ingredients:

• Amlodipine (5 mg): This is a calcium channel blocker that relaxes and widens blood vessels by inhibiting the movement of calcium ions into smooth muscle cells in the heart and blood vessels. This action reduces the resistance against which the heart pumps blood, thereby lowering blood pressure.
• Telmisartan (80 mg): This is an angiotensin II receptor antagonist (ARB). It blocks the effects of angiotensin II, a hormone that causes blood vessels to narrow and increases blood pressure. By blocking this hormone, Telmisartan promotes blood vessel relaxation and widening, and reduces water retention, further contributing to blood pressure reduction. Together, these components provide more comprehensive blood pressure control.

What is the usual dosage of AMLOSAFE TM 80 MG Tablet?

The dosage of AMLOSAFE TM 80 MG Tablet should be taken exactly as prescribed by your doctor. Typically, it is taken once daily, with or without food. It is important to swallow the tablet whole with water and not to crush or chew it. Do not exceed the prescribed dose without consulting your doctor.

What are the possible side effects of AMLOSAFE TM 80 MG Tablet?

Common side effects may include headache, dizziness, nausea, back pain, fatigue, peripheral oedema (swelling in the limbs), flushing, palpitations, and sleepiness. Some individuals might also experience a sudden drop in blood pressure, a racing heartbeat, abdominal pain, or diarrhea. Most of these side effects are temporary and usually resolve over time. However, if you experience severe side effects or if any symptoms persist or worsen, such as severe low blood pressure, unexplained swelling or weight gain, chest pain, or high blood potassium levels, you should consult your doctor immediately.

Is AMLOSAFE TM 80 MG Tablet safe during pregnancy or breastfeeding?

Pregnancy: AMLOSAFE TM 80 MG Tablet is considered unsafe and is not recommended during pregnancy, particularly during the second and third trimesters, due to definite evidence of risk to the developing baby. In rare, life-threatening situations, a doctor might weigh the benefits against the potential risks. If you are pregnant, planning to become pregnant, or become pregnant while taking this medication, you should consult your doctor immediately.

Breastfeeding: The use of AMLOSAFE TM 80 MG Tablet is generally not recommended during breastfeeding as its components may pass into breast milk and potentially harm the baby. An alternative treatment should be preferred, and it is crucial to consult your doctor if you are breastfeeding.

Can AMLOSAFE TM 80 MG Tablet be taken with other medications?

AMLOSAFE TM 80 MG Tablet can interact with various medications. It's important to inform your doctor about all prescription, over-the-counter, and herbal supplements you are taking.

• Potassium-sparing diuretics (e.g., amiloride, spironolactone) and potassium supplements: May increase the risk of high potassium levels in the blood (hyperkalemia).
• Non-steroidal anti-inflammatory drugs (NSAIDs) like ibuprofen or naproxen: Can reduce the blood pressure-lowering effects and increase the risk of kidney problems.
• Digoxin (a heart medication): Telmisartan may increase its blood levels.
• Statins (e.g., simvastatin): Blood levels of simvastatin may be increased.
• Aliskiren: Its use is not recommended, especially in elderly patients with diabetes or kidney disease, due to increased risks of kidney impairment and low blood pressure.
• Antifungal drugs (e.g., ketoconazole, itraconazole) and certain antibiotics (e.g., erythromycin, clarithromycin): May increase the blood levels of Telmisartan.
• Other blood pressure medications: May enhance the blood pressure-lowering effect, potentially causing very low blood pressure.
• Insulin or other antidiabetic medicines: May alter blood sugar levels, requiring dose adjustments.

What precautions should be taken while using AMLOSAFE TM 80 MG Tablet?

• Alcohol: Limit or avoid alcohol consumption as it can increase the risk of dizziness and further lower blood pressure.
• Liver and Kidney Conditions: Use with caution if you have liver or kidney disease. Your doctor may need to adjust the dosage.
• Heart Conditions: Exercise caution if you have severe congestive heart failure or other heart conditions.
• Diabetes: Close monitoring of blood sugar levels is recommended as the medicine can affect glucose control.
• Driving and Operating Machinery: This medication can cause dizziness, tiredness, or sleepiness. Avoid driving or operating heavy machinery until you understand how the medicine affects you.
• Dehydration: Inform your doctor if you have severe dehydration or low blood pressure volume.
• Grapefruit Juice: Avoid consuming grapefruit or grapefruit juice, as it may interact with the medication and increase blood levels of its components, leading to a higher risk of side effects.
• Regular Monitoring: Regular monitoring of blood pressure and kidney function tests may be necessary during treatment.
• Do not stop taking the medicine abruptly without consulting your doctor, as this can cause your blood pressure to rise.

What happens if a dose of AMLOSAFE TM 80 MG Tablet is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

How should AMLOSAFE TM 80 MG Tablet be stored?

Store AMLOSAFE TM 80 MG Tablet in a cool and dry place, away from direct sunlight, typically below 30°C. Keep it out of sight and reach of children.