Eltroxin 100 Mg

ELTROXIN 100 MG Tablets

ELTROXIN 100 MG is a thyroid hormone replacement medication manufactured by GlaxoSmithKline Pharmaceuticals Ltd.

Name

• Common Name: Levothyroxine sodium (or Thyroxine)
• Brand Name: ELTROXIN

Composition

Each ELTROXIN 100 MG tablet contains 100 micrograms of anhydrous levothyroxine sodium as the active ingredient. Inactive ingredients include microcrystalline cellulose, maize starch, purified talc, colloidal anhydrous silica, and magnesium stearate. Some formulations may also include acacia powder and lactose.

Uses

ELTROXIN is prescribed for the management of thyroid hormone deficiency, a condition known as hypothyroidism or underactive thyroid. It works by replacing the natural thyroid hormone (thyroxine) that the body is not producing in sufficient amounts. This helps to restore normal metabolic function and alleviate symptoms such as tiredness, weight gain, feeling cold, slow heart rate, dry skin, hair loss, and depression. It can also be used to suppress thyrotropin (TSH) for the management of TSH responsive tumors of the thyroid.

Dosage and Administration

The typical starting dose for adults is 50 to 100 micrograms daily, taken on an empty stomach, preferably 30-60 minutes before breakfast. The dose may be adjusted over time by a doctor based on individual response and blood test results. Lower doses are often used in the elderly and children, and for patients with cardiac conditions, initial doses might be as low as 12.5 to 25 micrograms. It is crucial to follow the doctor's instructions exactly and not to change the dose or switch brands without medical advice.

Side Effects

Common side effects are often associated with doses that are too high and may include headache, nervousness, sleeplessness, irritability, diarrhea, muscle spasm, weight loss, increased sweating, flushing, menstrual irregularities, and skin rash. More serious side effects can include rapid or irregular heartbeats, chest pain, increased blood pressure, and in rare cases, allergic reactions.

Precautions

• Medical Conditions: Caution is advised for patients with heart problems (angina, coronary artery disease, high blood pressure), diabetes, or adrenal insufficiency. ELTROXIN may affect blood sugar levels, requiring adjustments in antidiabetic medication.
• Interactions: Various substances can affect levothyroxine absorption or effectiveness. These include iron, calcium, magnesium, and aluminum supplements, antacids, proton pump inhibitors, soybean flour, and certain medications like orlistat, rifampicin, phenytoin, and amiodarone. A gap of at least 4 hours between taking ELTROXIN and these interacting agents is generally recommended.
• Bone Health: Long-term use or excessive doses may affect bone density, potentially leading to osteoporosis.
• Weight Loss: ELTROXIN should not be used for weight loss in individuals with normal thyroid function, as it can cause serious side effects.
• Pregnancy and Breastfeeding: Consult a doctor if pregnant or breastfeeding; dose adjustments may be necessary.

Storage

ELTROXIN tablets should be stored below 25°C in their original package, protected from light, and with the bottle tightly closed. They should not be stored in a bathroom or near a sink, as heat and dampness can degrade the medicine. Do not take tablets if their color has changed or if the expiry date has passed. Keep out of reach of children.

ELTROXIN 100 MG, manufactured by GlaxoSmithKline Pharmaceuticals Ltd., is a synthetic thyroid hormone used to treat an underactive thyroid gland (hypothyroidism). It works by replacing the hormone thyroxine that the body's thyroid gland cannot produce in sufficient quantities.

Here are some frequently asked questions about ELTROXIN 100 MG:

What is ELTROXIN 100 MG used for?

ELTROXIN 100 MG is primarily used to treat hypothyroidism, a condition where the thyroid gland doesn't produce enough thyroid hormones. This medication helps replace the missing thyroid hormone, thyroxine, which is crucial for regulating the body's metabolism, energy levels, mood, and other vital functions. It can also be used for certain TSH-responsive tumors of the thyroid gland.

How does ELTROXIN 100 MG work?

ELTROXIN 100 MG contains levothyroxine sodium, which is a synthetic version of the naturally occurring thyroid hormone thyroxine (T4). It works by supplementing the body with this hormone, thereby restoring normal thyroid hormone levels and regulating metabolic processes, cell growth, and differentiation. Levothyroxine is converted in peripheral tissues to triiodothyronine (T3), which is the active form of the thyroid hormone.

What is the usual dosage of ELTROXIN 100 MG?

For adults, the usual starting dose is 50 to 100 micrograms daily, which may be increased over time. The average adult maintenance dose typically ranges from 100 to 200 micrograms daily. Lower doses are often used for elderly patients or children. The exact dose will be determined and monitored by your doctor based on your blood tests and individual response. ELTROXIN should be taken as a single daily dose, preferably in the morning on an empty stomach, at least 30 to 60 minutes before food or other medications.

What are the possible side effects of ELTROXIN 100 MG?

Side effects are often seen when the medication is taken at higher doses than needed. Common side effects can include headache, nervousness, sleeplessness, irritability, diarrhea, muscle cramps or weakness, weight loss, increased appetite, heat intolerance, excessive sweating, flushing, and menstrual irregularities. More serious side effects, though less common, can include chest pain, rapid or irregular heartbeats, and allergic reactions such as skin rash or swelling of the face or throat. If you experience severe or bothersome side effects, or signs of too much medication, contact your doctor immediately.

Is ELTROXIN 100 MG safe during pregnancy or breastfeeding?

Yes, ELTROXIN can generally be taken during pregnancy and while breastfeeding. However, thyroid hormone levels need to be closely monitored during pregnancy, and your dosage may need to be increased to meet the higher demand for thyroid hormone. Small amounts of ELTROXIN pass into breast milk, but these are considered negligible and generally harmless to the baby. Discuss any concerns with your doctor.

Can ELTROXIN 100 MG be taken with other medications?

ELTROXIN can interact with several other medications, affecting its absorption or efficacy, or the efficacy of the other drugs. It is important to inform your doctor about all medications you are taking, including over-the-counter drugs, herbal supplements, and vitamins.

Some medications that may interact include:

• Antacids, calcium, iron, and magnesium supplements: These can decrease ELTROXIN absorption. It's recommended to take ELTROXIN at least 4 hours apart from these.
• Certain antidepressants: Such as SSRIs and tricyclic antidepressants.
• Anticoagulants (e.g., Warfarin): ELTROXIN can increase their effect, potentially requiring a dosage adjustment of the anticoagulant.
• Medicines for diabetes (e.g., insulin): ELTROXIN may raise blood sugar levels, necessitating adjustment of antidiabetic medication.
• Epilepsy medications (e.g., phenytoin, carbamazepine): These can enhance the metabolism of thyroid hormones.
• Proton pump inhibitors (PPIs): Co-administration may decrease the absorption of thyroid hormones.
• Orlistat (weight loss drug): May decrease levothyroxine absorption; administer at least 4 hours apart.
• Soy-containing compounds and high-fiber diets: Can decrease intestinal absorption.

What precautions should be taken when using ELTROXIN 100 MG?

It is crucial to follow your doctor's instructions carefully and not to change your dose without consulting them. ELTROXIN should not be used for weight loss in individuals with normal thyroid function, as it can cause serious side effects. Exercise caution if you have heart conditions (like angina or high blood pressure), diabetes, or adrenal gland disorders. Regular blood tests are necessary to monitor your thyroid hormone levels and ensure the medication is working effectively. Do not switch brands of levothyroxine without consulting your doctor, as different brands may not have the same effect.

What happens if a dose of ELTROXIN 100 MG is missed?

If you miss a dose, take it as soon as you remember. However, if it's almost time for your next scheduled dose, skip the missed one and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. Missing one or two doses usually won't cause noticeable symptoms, but consistently missing doses can lead to a return of hypothyroidism symptoms. If you are unsure, consult your doctor or pharmacist.

How should ELTROXIN 100 MG be stored?

ELTROXIN tablets should be stored below 25°C in their original packaging, protected from light and moisture. Keep the bottle tightly closed and out of reach of children. Do not store it in a bathroom or near a sink, as heat and dampness can degrade the medication. Check the expiry date and do not use the medication if the tablets' color has changed.