Amazeo Od 200 Mg

AMAZEO OD 200 MG Tablet, manufactured by Torrent Pharmaceuticals Ltd., is an atypical antipsychotic medication primarily used for the management of schizophrenia. The "OD" in its name signifies "Once Daily," indicating its sustained-release formulation designed for convenient single daily dosing.

Name

• Brand Name: Amazeo OD 200 MG
• Common Name: Amisulpride

Composition

• Active Ingredient: Amisulpride (200 mg)

Uses

Amazeo OD 200 MG is prescribed for:

• Schizophrenia: It treats both acute and chronic schizophrenic disorders, addressing positive symptoms (such as delusions, hallucinations, and thought disorders) and negative symptoms (like blunted affect, emotional and social withdrawal).
• Postoperative Nausea/Vomiting: It is also used to prevent nausea and vomiting that may occur after surgery.

Dosage and Administration

Amazeo OD 200 MG tablets are for oral consumption and should be swallowed whole with water; they should not be crushed, chewed, or broken. It can be taken with or without food, preferably at the same time each day to maintain consistent medication levels. Doses up to 300 mg can be taken once daily, while doses exceeding 300 mg are typically divided into two portions (morning and evening). Your doctor will determine the appropriate dosage, which can range from 50 mg to 800 mg daily, and sometimes up to 1200 mg daily in individual cases.

Side Effects

Common Side Effects:

• Drowsiness, sleepiness, blurred vision, dizziness
• Nausea, vomiting, constipation, dry mouth
• Weight gain
• Increased prolactin levels (may cause breast pain, unusual breast milk production, menstrual irregularities, erectile dysfunction, gynecomastia)
• Difficulty sleeping (insomnia), anxiety, agitation
• Extrapyramidal symptoms (e.g., tremors, rigidity, involuntary muscle contractions like dystonia, akathisia)

Serious Side Effects:

• Severe allergic reactions (swelling of face/throat, difficulty breathing/swallowing, rash)
• Seizures or fits
• Neuroleptic Malignant Syndrome (high temperature, stiff muscles, fast heartbeat/breathing, confusion)

Precautions

• Pregnancy and Breastfeeding: Not recommended during pregnancy or for breastfeeding mothers due to potential harm to the child.
• Children and Elderly: Contraindicated in children under 18. Use with caution in elderly patients due to increased risk of side effects.
• Alcohol: Avoid alcohol consumption as it may worsen side effects like drowsiness.
• Driving/Machinery: Avoid driving or operating heavy machinery if experiencing drowsiness, dizziness, or blurred vision.
• Medical Conditions: Inform your doctor if you have a history of diabetes, Parkinson's disease, kidney or liver dysfunction, heart conditions (especially those predisposing to QT prolongation), breast cancer or prolactin-dependent tumors, pheochromocytoma, or a history of seizures.
• Drug Interactions: Avoid concomitant use with levodopa, medications affecting heart rhythm, and exercise caution with other sedatives, diuretics, laxatives, and other antipsychotics/antidepressants/anti-seizure medications. Do not stop taking the medicine suddenly without consulting your doctor, as it can worsen symptoms or cause withdrawal effects.

Storage

Store the medicine below 30°C or at room temperature. Keep out of sight and reach of children.

AMAZEO OD 200 MG contains Amisulpride as its active ingredient, which is an atypical antipsychotic medication. It is manufactured by Torrent Pharmaceuticals Ltd..

What is AMAZEO OD 200 MG used for?

AMAZEO OD 200 MG is primarily used to treat schizophrenia, a mental health condition characterized by disturbed thinking, emotions, perception of reality, and behavior. It helps manage both positive symptoms, such as delusions, hallucinations, and disorganized thinking, and negative symptoms, including apathy, emotional withdrawal, and reduced motivation.

How does AMAZEO OD 200 MG work?

AMAZEO OD 200 MG works by selectively blocking dopamine D2 and D3 receptors in the brain. By modulating dopamine and serotonin activity, it helps to improve disturbed thoughts, feelings, and behavior associated with schizophrenia. At lower doses, it can also enhance dopamine activity, which may help improve mood and reduce negative symptoms.

What is the usual dosage for AMAZEO OD 200 MG?

The dosage of Amisulpride (the active ingredient in AMAZEO OD 200 MG) varies depending on the symptoms and individual patient response. For acute psychotic episodes, doses between 400 mg/day and 800 mg/day are commonly recommended, and in some cases, the daily dose may be increased up to 1200 mg/day. For patients with predominant negative symptoms, oral doses typically range from 50 mg/day to 300 mg/day. Doses up to 300 mg daily can be taken as a single dose, preferably at the same time each day, while higher doses should be split into morning and evening administrations. Your doctor will determine the appropriate dose and duration of treatment.

What are the possible side effects of AMAZEO OD 200 MG?

Common side effects can include drowsiness or sleepiness, anxiety, agitation, difficulty sleeping (insomnia), constipation, nausea, vomiting, dry mouth, weight gain, blurred vision, dizziness (which can be due to low blood pressure), and difficulty in getting or maintaining an erection. Hormonal changes, such as increased prolactin levels, may lead to breast pain, unusual breast milk production, or menstrual irregularities in women, and breast enlargement in men. More serious but rare side effects include irregular heartbeat, seizures, and a potentially fatal condition called Neuroleptic Malignant Syndrome (characterized by high fever, muscle stiffness, and altered consciousness).

Is AMAZEO OD 200 MG safe during pregnancy or breastfeeding?

AMAZEO OD 200 MG is not recommended during pregnancy, and its safety in human pregnancy has not been established. Animal studies have shown harmful effects on the fetus. If used during the last three months of pregnancy, the baby may experience symptoms like agitation, increased muscle tension, tremors, sleepiness, breathing problems, or feeding difficulties. You should not breastfeed while taking Amisulpride, as it can pass into breast milk in significant amounts. Your doctor will discuss the risks and benefits if treatment is necessary.

Can AMAZEO OD 200 MG be taken with other medications?

AMAZEO OD 200 MG can interact with several medications. It is not recommended with levodopa (used for Parkinson's disease) as they have opposing effects. Caution is advised with other sedatives, heart medications, antimalarial medicines, antihistamines, and drugs that lower blood potassium levels (like diuretics and laxatives). It can also enhance the effects of alcohol, leading to increased drowsiness. Always inform your doctor about all other medicines, supplements, or herbal remedies you are taking.

What precautions should be taken while taking AMAZEO OD 200 MG?

Inform your doctor if you have kidney problems, diabetes, Parkinson's disease, epilepsy (fits), an unusual heart rate, or low potassium levels in your blood. Special care is needed for elderly patients due to a higher risk of low blood pressure or sleepiness. It is also not recommended if you have breast cancer, a prolactin-dependent tumor, or a tumor on your adrenal gland (phaeochromocytoma). Avoid driving or operating heavy machinery if you experience drowsiness, blurred vision, or slow reflexes.

What happens if a dose of AMAZEO OD 200 MG is missed?

If you forget to take a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a forgotten tablet.

How should AMAZEO OD 200 MG be stored?

AMAZEO OD 200 MG tablets should be stored in a cool, dry place, ideally below 25°C or 30°C, and away from direct sunlight and moisture. Keep the medicine out of the sight and reach of children. Do not store it in the bathroom or near a sink.