Mpride 1 Tab

MPRIDE 1 Tablet

Mpride 1 Tablet is an oral anti-diabetic medication manufactured by Ajanta Medicals Pvt. Ltd., used for the management of Type 2 Diabetes Mellitus. It is a combination therapy designed to help control high blood sugar levels in adults when diet and exercise alone are insufficient.

Composition Each Mpride 1 Tablet typically contains:

• Glimepiride: 1 mg
• Metformin: 500 mg

Glimepiride, a sulfonylurea, stimulates the pancreas to release more insulin. Metformin, a biguanide, works by reducing glucose production in the liver, delaying glucose absorption from the intestines, and improving the body's sensitivity to insulin.

Uses Mpride 1 Tablet is prescribed for the treatment of Type 2 Diabetes Mellitus in adults. It aids in controlling blood sugar levels, improving insulin sensitivity, and reducing the risk of diabetes-related complications such as kidney damage, eye problems, nerve issues, heart problems, and stroke.

Dosage and Administration The tablet should be taken orally as prescribed by a doctor, usually once a day with food to minimize stomach upset. It should be swallowed whole without crushing or chewing. The dosage is determined by the physician based on the patient's condition and response to treatment, and it is crucial not to exceed the recommended dose or discontinue the medicine without consulting a doctor.

Side Effects Common side effects may include:

• Hypoglycemia (low blood sugar), with symptoms like sweating, dizziness, headache, and shaking
• Nausea, vomiting, diarrhea, abdominal pain
• Headache
• Metallic taste
• Taste changes
• Weight gain
• Upper respiratory tract infections

Serious but rare side effects can include lactic acidosis and, with long-term use, vitamin B12 deficiency.

Precautions

• Contraindications: Not recommended for patients with Type 1 Diabetes Mellitus, diabetic ketoacidosis, severe kidney or liver disease, or known allergy to its components.
• Pregnancy and Breastfeeding: Should not be used during pregnancy as it may harm the unborn baby. It is also advised against during breastfeeding as the medicine may pass into breast milk.
• Alcohol Consumption: Avoid excessive alcohol intake as it increases the risk of hypoglycemia and serious complications like lactic acidosis.
• Medical Conditions: Use with caution in patients with liver problems, kidney problems, or heart disease.
• Driving and Machinery: May cause dizziness or tiredness due to low blood sugar; caution is advised while driving or operating machinery.
• Drug Interactions: Certain medications like thiazides, corticosteroids, oral contraceptives, and estrogen may reduce its blood sugar-lowering effect. H2 blockers (e.g., cimetidine) and carbonic anhydrase inhibitors (e.g., acetazolamide) may increase metformin levels or the risk of lactic acidosis.
• Monitoring: Regular monitoring of blood sugar levels is essential.

Storage Store Mpride 1 Tablet at room temperature, typically below 30°C. Protect the product from both light and moisture to maintain its efficacy. Ensure it is stored out of the reach of children.

What is Mpride 1 Tablet used for?

Mpride 1 Tablet is primarily used to treat type 2 diabetes mellitus in adults. It helps control high blood sugar levels when diet and exercise alone are not sufficient, thereby reducing the risk of diabetes-related complications such as kidney damage, eye problems, nerve issues, and cardiovascular diseases.

How does Mpride 1 Tablet work?

Mpride 1 Tablet contains two active ingredients: Glimepiride and Metformin. Glimepiride, a sulfonylurea, works by stimulating the beta cells in the pancreas to produce and release more insulin, which helps lower blood sugar levels. Metformin, a biguanide, acts by reducing the amount of glucose produced by the liver, delaying the absorption of glucose from the intestines, and improving the body's sensitivity to insulin, allowing cells to utilize glucose more effectively.

What is the usual dosage for Mpride 1 Tablet?

The dosage of Mpride 1 Tablet is determined by your doctor based on your individual condition and response to treatment. It is typically taken orally once a day with food, preferably with the first meal of the day. It is crucial to follow your doctor's instructions and not to exceed the prescribed dosage.

What are the possible side effects of Mpride 1 Tablet?

Common side effects may include hypoglycemia (low blood sugar), nausea, vomiting, diarrhea, abdominal pain, headache, altered taste, loss of appetite, or a metallic taste. Less common but serious side effects can include lactic acidosis (a rare buildup of lactic acid in the blood) and, with long-term use, vitamin B12 deficiency. If you experience any severe or persistent side effects, you should consult your doctor.

Is Mpride 1 Tablet safe during pregnancy or breastfeeding?

Mpride 1 Tablet is generally not recommended during pregnancy as it may cause harm to the unborn baby. For breastfeeding mothers, it is also not advised as the medicine may pass into breast milk and potentially cause adverse effects in the infant. Always consult your doctor if you are pregnant, planning a pregnancy, or breastfeeding.

Can Mpride 1 Tablet be taken with other medications?

Mpride 1 Tablet can interact with various medications. These include other anti-diabetic drugs (like insulin or gliclazide, which can increase the risk of hypoglycemia), certain blood pressure medications (ACE inhibitors, Angiotensin II receptor antagonists), diuretics (thiazides), corticosteroids, oral contraceptives, and H2 blockers. It is essential to inform your doctor about all prescription drugs, over-the-counter medicines, and herbal supplements you are currently taking to avoid potential interactions.

What precautions should be taken while taking Mpride 1 Tablet?

You should avoid excessive alcohol intake while taking Mpride 1 Tablet, as it can increase the risk of low blood sugar and a serious condition called lactic acidosis. Use with caution if you have kidney, liver, or heart disease. Regular monitoring of blood sugar levels is important. If you experience symptoms of low blood sugar (e.g., sweating, dizziness, headache), consume a quick source of sugar like fruit juice or glucose tablets. Mpride 1 Tablet is not suitable for type 1 diabetes or diabetic ketoacidosis. Inform your doctor if you have a planned surgery or diagnostic imaging that involves iodine injection.

What happens if a dose of Mpride 1 Tablet is missed?

If you miss a dose of Mpride 1 Tablet, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one, as this can lead to an unsafe drop in blood sugar. Missing a dose can result in high blood sugar levels.

How should Mpride 1 Tablet be stored?

Mpride 1 Tablet should be stored at room temperature, generally below 30°C (or between 20-25°C), and protected from both light and moisture to maintain its effectiveness. Keep the medicine out of the reach and sight of children. Always check the expiry date before use.