Desval Er 125 Mg

DESVAL ER 125 MG by ERIS LIFESCIENCES LIMITED

Name

• Brand Name: Desval ER 125 MG Tablet
• Common Name: Divalproex (Extended-Release)

Composition

Each DESVAL ER 125 MG tablet contains 125 mg of Divalproex Sodium (sustained-release formulation) as its active ingredient. Divalproex is a combination of sodium valproate and valproic acid.

Uses

DESVAL ER 125 MG is primarily prescribed for:

• Epilepsy/Seizures: It is used to control various types of seizures, including complex partial seizures, by decreasing abnormal electrical activity in the brain.
• Bipolar Disorder: It is used to treat manic episodes associated with bipolar disorder by restoring the balance of nerve activity in the brain and providing a calming effect.
• Migraine Prophylaxis: It is indicated for the prevention of migraine headaches.

Dosage and Administration

DESVAL ER 125 MG is typically administered once daily. The initial dose is often 125 mg, which may be adjusted by a doctor based on individual response and tolerance. It can be taken with or without food, but it is recommended to take it at the same time each day to maintain consistent medication levels. The tablet should be swallowed whole and not crushed, chewed, or broken. Missing a dose may trigger seizures, and abrupt discontinuation should be avoided as it can worsen the condition.

Side Effects

Common Side Effects:

• Headache
• Nausea, vomiting, abdominal pain
• Dizziness, drowsiness, sleepiness
• Tremor
• Diarrhea, constipation
• Weight gain or loss
• Hair loss
• Blurred vision, double vision
• Weakness, fatigue
• Rash

Serious Side Effects:

• Liver damage: Risk is higher during the first 6 months of treatment. Symptoms include nausea, vomiting, loss of appetite, stomach pain, dark urine, and jaundice. Liver function tests are recommended before and during treatment.
• Pancreatitis
• Suicidal thoughts and behaviors
• Bleeding problems (e.g., bruising, red or purple spots on the skin)
• High ammonia levels in the blood (hyperammonemia)
• Low body temperature (hypothermia)
• Serious skin reactions (e.g., skin rash, hives, blistering)
• Osteoporosis (reduced bone mass) with long-term use

Precautions

• Pregnancy: DESVAL ER 125 MG is not recommended during pregnancy or if planning a pregnancy, as it can cause serious developmental defects and decreased IQ in the baby. Effective contraception should be used by women of childbearing age.
• Breastfeeding: Use with caution and only if recommended by a doctor, as it passes into breast milk.
• Liver Disease: Contraindicated in patients with acute or chronic hepatitis, a history of liver damage, or significant liver dysfunction.
• Kidney Problems: Use with caution; dose adjustment may be needed.
• Alcohol: Avoid alcohol consumption as it can increase dizziness and drowsiness.
• Driving and Operating Machinery: Avoid these activities as the medicine can cause dizziness, drowsiness, and affect focus.
• Drug Interactions: Inform your doctor about all other medications and supplements, especially lamotrigine, warfarin, oral contraceptives, and antidepressants, as interactions can occur.
• Children: Not recommended for children below 2 years of age due to a higher risk of liver intoxication. Use with caution in other pediatric patients.
• Other Conditions: Caution is advised in patients with depression, suicidal thoughts, urea cycle disorders, porphyria, pancreatitis, or systemic lupus erythematosus.

Storage

DESVAL ER 125 MG tablets should be stored at room temperature, below 30°C, away from light and moisture. Keep out of reach of children and pets.

Important Note on Active Ingredient:

There appears to be conflicting information regarding the active ingredient of "DESVAL ER 125 MG by ERIS LIFESCIENCES LIMITED". While some sources erroneously list desvenlafaxine, a serotonin-norepinephrine reuptake inhibitor (SNRI) for depression, the majority of direct and reliable sources for "DESVAL ER 125 MG" from ERIS LIFESCIENCES LIMITED confirm that its active ingredient is Divalproex (125mg), an anticonvulsant. The following FAQs are based on Divalproex 125mg Extended-Release.

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What is DESVAL ER 125 MG used for?

DESVAL ER 125 MG (Divalproex) is primarily used to treat various forms of epilepsy, including partial seizures, complex partial seizures, and absence seizures. It is also prescribed to prevent migraine headaches and to manage manic episodes associated with bipolar disorder.

How does DESVAL ER 125 MG work?

DESVAL ER 125 MG contains Divalproex, which is an antiepileptic medication. It works by decreasing the abnormal and excessive electrical activity of nerve cells in the brain. It achieves this by increasing the levels of a chemical substance called GABA, a neurotransmitter that helps block nerve transmission across the brain, thereby providing a calming effect and controlling seizures.

What is the usual dosage of DESVAL ER 125 MG?

The dose and frequency of taking DESVAL ER 125 MG will be determined by your doctor based on your medical condition. It is typically taken once a day with or without food, but it's important to take it at the same time each day to get the most benefit. The extended-release tablets should be swallowed whole and not chewed, crushed, or broken.

What are the possible side effects of DESVAL ER 125 MG?

Common side effects of DESVAL ER 125 MG can include nausea, vomiting, abdominal pain, diarrhea, dizziness, headache, drowsiness, tremor, and hair loss. More serious side effects can include fatigue, loss of coordination, blurred vision, and mood or behavioral changes. If side effects persist or worsen, consult your doctor.

Is DESVAL ER 125 MG safe during pregnancy or breastfeeding?

DESVAL ER 125 MG is generally considered unsafe during pregnancy as there is definite evidence of risk to the developing baby, and it could cause serious birth defects. Women of childbearing age should use effective contraception while taking this medicine. It is generally considered safe to use during breastfeeding, as human studies suggest the drug does not pass into breast milk in significant amounts and is not harmful to the baby. However, always consult your doctor if you are pregnant, planning a pregnancy, or breastfeeding.

Can DESVAL ER 125 MG be taken with other medications?

DESVAL ER 125 MG can interact with various other medicines. It's crucial to inform your doctor about all medications, supplements, and herbal products you are currently taking, especially other anti-epileptic medicines (like phenytoin), anti-migraine medicines, antidepressants, pain killers, immunomodulatory medicines, contraceptives, warfarin (blood thinners), zidovudine (for HIV), anti-cancer medicines, selegiline, diazepam, quetiapine, and propofol. Concurrent use with certain drugs can increase their effects or the risk of side effects.

What precautions should be taken while taking DESVAL ER 125 MG?

Before taking DESVAL ER 125 MG, inform your doctor if you have liver problems (as it is not recommended for use in patients with liver disease), kidney problems, or any other medical conditions. This medicine can cause dizziness or drowsiness, so avoid driving or operating machinery until you know how it affects you. Alcohol consumption should be avoided as it may lead to excessive drowsiness. Do not stop taking the medication abruptly, as this can lead to withdrawal symptoms or increased seizure frequency.

What happens if a dose of DESVAL ER 125 MG is missed?

If you miss a dose of DESVAL ER 125 MG, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one, as this can increase the risk of side effects or lead to serious adverse effects like seizures.

How should DESVAL ER 125 MG be stored?

DESVAL ER 125 MG tablets should be stored in a cool and dry place, away from direct sunlight, and kept out of the sight and reach of children.