Stalix M 50+1000 Mg Tab

STALIX M 50+1000 MG Tablet

STALIX M 50+1000 MG Tablet, manufactured by Torrent Pharmaceuticals Ltd., is a combination medication used to manage Type 2 Diabetes Mellitus in adults. It effectively controls high blood sugar levels and helps prevent serious diabetes-related complications such as kidney damage, blindness, nerve problems, heart issues, and stroke.

• Name:

  • Brand Name: STALIX M 50+1000 MG Tablet
  • Common Name: Sitagliptin and Metformin Tablets

• Composition:

  • Active Ingredients: Each tablet contains Sitagliptin (50 mg) and Metformin (1000 mg).
    • Sitagliptin works by increasing insulin release from the pancreas and reducing glucagon secretion in a glucose-dependent manner, by inhibiting the DPP-4 enzyme.
    • Metformin reduces glucose production in the liver, decreases glucose absorption from the intestines, and enhances insulin sensitivity, improving glucose uptake and utilization in the body.

• Uses:

  • Management of Type 2 Diabetes Mellitus in adults.
  • Improves blood glucose control when either sitagliptin or metformin alone is insufficient.
  • Helps lower the risk of diabetes-related complications.

• Dosage and Administration:

  • Typically taken orally, once or twice daily, with food to minimize stomach upset.
  • Swallow the tablet whole with a glass of water; do not break, chew, or crush it.
  • Follow the dosage and duration as prescribed by your healthcare provider. Do not discontinue the medication without consulting your doctor.

• Side Effects:

  • Common Side Effects: Diarrhea, nausea, vomiting, abdominal pain/upset stomach, headache, upper respiratory tract infections (runny nose, sore throat, coughing), flatulence, and low blood sugar levels (hypoglycemia), especially when taken with other diabetes medicines like insulin or sulfonylurea.
  • Serious Side Effects (Rare): Severe allergic reactions (hives, swelling of face, lips, tongue, throat causing difficulty breathing/swallowing), severe blistering of the skin, signs of pancreatitis (severe persistent stomach pain with or without nausea/vomiting), and lactic acidosis (muscle pain, breathing difficulties, unusual fatigue, dizziness, weakness).

• Precautions:

  • Allergy: Avoid if allergic to any components of the medicine.
  • Kidney/Liver Disease: Use with caution in patients with kidney problems; not recommended for severe kidney or liver impairment due to increased risk of lactic acidosis. Regular monitoring of kidney function is advised.
  • Pregnancy and Breastfeeding: Generally not recommended. Consult your doctor if pregnant, planning to conceive, or breastfeeding.
  • Alcohol: Avoid alcohol consumption as it can increase the risk of lactic acidosis and hypoglycemia.
  • Other Conditions: Inform your doctor about any history of pancreatitis, heart disease, high blood cholesterol levels, severe systemic infections, or dehydration. Not for Type 1 Diabetes or diabetic ketoacidosis.
  • Drug Interactions: Inform your doctor about all other medications, supplements, or herbals you are taking to avoid potential interactions, especially with insulin, insulin secretagogues, or salicylates.

• Storage:

  • Store in a cool and dry place, away from direct sunlight.
  • Keep out of sight and reach of children.
  • Store at room temperature, typically not above 30°C.

What is Stalix M 50+1000 Tablet used for?

Stalix M 50+1000 Tablet is primarily used for the treatment of Type 2 diabetes mellitus in adults. It helps manage high blood sugar levels and plays a crucial role in preventing severe complications associated with diabetes, such as kidney damage, blindness, nerve problems, heart attacks, and strokes. It can be prescribed alone or in conjunction with other diabetes medications.

How does Stalix M 50+1000 Tablet work?

This medicine is a combination of two active ingredients: Sitagliptin (50mg) and Metformin (1000mg). Sitagliptin works by increasing insulin release from the pancreas and reducing glucagon secretion in a glucose-dependent manner, boosting the effects of natural substances called incretins. Metformin reduces glucose production in the liver, decreases the absorption of glucose from the intestines, and enhances the body's sensitivity to insulin. Together, these actions provide better control over blood sugar levels, especially after meals.

What is the usual dosage of Stalix M 50+1000 Tablet?

The dosage of Stalix M 50+1000 Tablet is determined by your doctor based on your individual condition, blood sugar levels, and other medications you may be taking. It is typically taken once or twice daily with food to minimize stomach upset. The tablet should be swallowed whole with a glass of water and not crushed, chewed, or broken.

What are the possible side effects of Stalix M 50+1000 Tablet?

Common side effects may include diarrhea, nausea, vomiting, upset stomach, headache, sore throat, upper respiratory tract infection, abdominal pain, decreased appetite, and metallic taste. Low blood sugar (hypoglycemia) can occur, especially if taken with other diabetes medications like insulin or sulfonylurea. Serious but rare side effects include lactic acidosis (symptoms like muscle pain, difficulty breathing, unusual fatigue, dizziness, cold extremities) and severe allergic reactions. Long-term use can also lead to Vitamin B12 deficiency.

Is Stalix M 50+1000 Tablet safe during pregnancy or breastfeeding?

Pregnancy: It is advised to consult your doctor before using Stalix M 50+1000 Tablet if you are pregnant or planning to conceive. Its safety during pregnancy has not been fully established, and some sources indicate it may be unsafe or contraindicated. It should only be used if the potential benefits clearly outweigh the risks.

Breastfeeding: It is generally considered probably unsafe to use during breastfeeding, as one of its components, Metformin, is known to be excreted into human breast milk and may harm the baby. Consult your doctor to discuss the safest feeding options for your baby.

Can Stalix M 50+1000 Tablet be taken with other medications?

It is crucial to inform your doctor about all other medications, supplements, or herbal products you are currently taking or plan to take to avoid potential drug interactions. Taking Stalix M 50+1000 Tablet with insulin or insulin secretagogues (e.g., glimepiride, gliclazide) or salicylates (e.g., aspirin) can increase the risk of low blood sugar. Other medications that may interact include ACE inhibitors, ARBs, corticosteroids, diuretics, cimetidine, rifampin, beta-blockers, digoxin, and NSAIDs.

What precautions should be taken while using Stalix M 50+1000 Tablet?

Before starting this medicine, inform your doctor if you have kidney, liver, or heart disease, pancreatic issues, or a history of pancreatitis, low vitamin B12 levels, severe infections, or dehydration. It is not suitable for Type 1 diabetes or diabetic ketoacidosis. Avoid excessive alcohol consumption, as it can increase the risk of lactic acidosis and hypoglycemia. Regular monitoring of kidney function and blood sugar levels is recommended. Continue a healthy diet and regular exercise as advised by your doctor. If you experience dizziness, exercise caution when driving or operating machinery.

What happens if a dose of Stalix M 50+1000 Tablet is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

How should Stalix M 50+1000 Tablet be stored?

Stalix M 50+1000 Tablet should be stored in a cool, dry place, away from direct sunlight. Keep it tightly closed in its original container and out of the sight and reach of children.