Empasov M Xr 12.5/1000mg Tab

EMPASOV M XR 12.5/1000MG Tablet

Name

Brand Names: Empasov M XR 12.5/1000 Tablet, Empasov M-XR 12.5/1000, Empasav M XR 12.5/1000mg.

Composition

EMPASOV M XR 12.5/1000MG Tablet contains two active ingredients:

• Empagliflozin (12.5 mg): A sodium-glucose cotransporter 2 (SGLT2) inhibitor. It works by blocking SGLT2 in the kidneys, leading to increased glucose removal through urine, thereby lowering blood sugar levels.
• Metformin (1000 mg): A biguanide. Metformin reduces glucose production by the liver, delays glucose absorption from the intestines, and increases the body's sensitivity to insulin, helping cells use glucose more effectively.

Uses

EMPASOV M XR 12.5/1000MG Tablet is primarily used for:

• Improving blood sugar control in adults with Type 2 Diabetes Mellitus, as an adjunct to diet and exercise.
• Reducing the risk of cardiovascular death in patients with established heart disease and Type 2 Diabetes.
• Preventing serious complications of diabetes such as kidney damage, eye damage, nerve problems, and limb loss.

Dosage and Administration

• Typically taken once daily.
• It can be taken with or without food, but it is often recommended to take it with food to reduce gastrointestinal discomfort.
• Swallow the tablet whole with water; do not chew, crush, or break it.
• Take it at the same time every day for optimal benefits.
• The exact dose and duration will be determined by your doctor. Do not discontinue the medicine without consulting your doctor.

Side Effects

Common Side Effects:

• Urinary tract infections (UTIs)
• Female genital mycotic (yeast) infections
• Nausea, vomiting, diarrhea, flatulence, abdominal discomfort, indigestion
• Frequent urination
• Hypoglycemia (low blood sugar), especially when used with other antidiabetic medicines or alcohol
• Taste changes, joint pain

Serious Side Effects (consult your doctor immediately if experienced):

• Lactic acidosis (rare but serious, symptoms include unusual muscle pain, trouble breathing, stomach pain, weakness, irregular heartbeat).
• Dehydration, dizziness, or lightheadedness, particularly in the elderly or those on diuretics.
• Ketoacidosis (a serious life-threatening condition).

Precautions

• Allergy: Do not use if allergic to empagliflozin, metformin, or any other ingredients.
• Pregnancy and Breastfeeding: Not recommended during pregnancy or breastfeeding, as safety has not been established.
• Kidney and Liver Impairment: Use with caution; not recommended in severe kidney or liver impairment. Your doctor will assess kidney function.
• Alcohol: Avoid or limit alcohol consumption as it can increase the risk of lactic acidosis and affect blood sugar levels.
• Dehydration: Drink plenty of fluids to prevent dehydration, especially in hot weather or during exercise.
• Drug Interactions: Inform your doctor about all medications, supplements, and herbals you are taking, especially diuretics, insulin, sulfonylureas, corticosteroids, and certain blood pressure medications.
• Medical Conditions: Caution is advised in patients with severe infections, uncontrolled diabetes, fasting for long durations, or a history of heart failure.
• Driving: May cause dizziness or drowsiness; avoid driving or operating machinery until you know how it affects you.

Storage

• Store in a cool and dry place, preferably at room temperature.
• Keep away from direct sunlight and moisture.
• Keep out of reach and sight of children and pets.
• Maintain the original packaging tightly sealed.

EMPASOV M XR 12.5/1000MG TAB is a medication containing Empagliflozin (12.5mg) and Metformin (1000mg) in an extended-release formulation, used to manage type 2 diabetes.

What is EMPASOV M XR 12.5/1000MG TAB used for?

EMPASOV M XR 12.5/1000MG TAB is used to treat type 2 diabetes mellitus in adults, in conjunction with diet and exercise, to improve blood sugar control. It also helps reduce the risk of cardiovascular death in adults with type 2 diabetes and established cardiovascular disease, and can reduce the risk of cardiovascular death and hospitalization for heart failure or progression of chronic kidney disease.

How does EMPASOV M XR 12.5/1000MG TAB work?

This medicine contains two active ingredients: Empagliflozin and Metformin. Empagliflozin works by blocking the sodium-glucose co-transporter-2 (SGLT2) in the kidneys, which increases the amount of sugar removed from the body through urine. Metformin works by decreasing glucose production in the liver, reducing glucose absorption from the intestines, and increasing the body's sensitivity to insulin. Together, these actions more effectively lower blood glucose levels.

What is the usual dosage for EMPASOV M XR 12.5/1000MG TAB?

The typical dosage is usually once daily in the morning, taken orally. It can be taken with or without food, but taking it with meals may help reduce stomach upset. Tablets should be swallowed whole and not chewed, crushed, or broken. The specific dose will be determined by your doctor based on your medical condition and response to treatment, but generally, the daily dose does not exceed 25mg of Empagliflozin and 2000mg of Metformin.

What are the possible side effects of EMPASOV M XR 12.5/1000MG TAB?

Common side effects may include frequent urination, nausea, vomiting, diarrhea, stomach ache, loss of appetite, urinary tract infections, and female genital mycotic infections. More serious but less common side effects can include lactic acidosis, severe dehydration, diabetic ketoacidosis, and hypoglycemia (low blood sugar), particularly when used with other antidiabetic medicines or alcohol.

Is EMPASOV M XR 12.5/1000MG TAB safe during pregnancy or breastfeeding?

EMPASOV M XR 12.5/1000MG TAB is generally not recommended during pregnancy, especially in the second and third trimesters, due to potential risks to the unborn baby's kidney development. For breastfeeding mothers, it is also not recommended as Empagliflozin may pass into breast milk and pose a theoretical risk to the infant's developing kidneys. Your doctor may suggest alternative, safer treatments during these periods.

Can EMPASOV M XR 12.5/1000MG TAB be taken with other medications?

Caution is advised when taking EMPASOV M XR with other medications. Diuretics (water pills) can increase the risk of dehydration. Insulin or insulin secretagogues may increase the risk of low blood sugar. Corticosteroids can increase blood sugar levels, potentially reducing the effectiveness of EMPASOV M XR. It is crucial to inform your doctor about all prescription, over-the-counter medications, supplements, and herbal products you are taking to avoid potential interactions. Alcohol consumption should be avoided due to an increased risk of lactic acidosis and hypoglycemia.

What precautions should be taken while using EMPASOV M XR 12.5/1000MG TAB?

Do not take this medicine if you are allergic to its components, have type 1 diabetes, or have severe kidney or liver disease, or metabolic acidosis. It's important to monitor your blood sugar regularly and stay well-hydrated, especially if experiencing vomiting, diarrhea, or heavy sweating. Do not stop taking the medication abruptly without consulting your doctor. Elderly patients may require more frequent monitoring of kidney function.

What happens if a dose of EMPASOV M XR 12.5/1000MG TAB is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

How should EMPASOV M XR 12.5/1000MG TAB be stored?

Store the medication in a cool, dry place, away from direct sunlight, heat, and moisture. Keep it in its original closed container and out of reach of children and pets. Do not allow it to freeze.