Glador M2 Fortetablet (15 Tab)

GLADOR M2 FORTE TABLET (15 TAB) by LUPIN LTD.

GLADOR M2 Forte Tablet is a combination medication specifically designed for the management of Type 2 Diabetes Mellitus in adults. It works to improve blood glucose control when diet, exercise, and single-agent therapy are insufficient.

• Name:

  • Brand Name: GLADOR M2 Forte Tablet
  • Common Name: Glimepiride and Metformin Tablets

• Composition:

  • Active Ingredients: Each tablet contains Glimepiride (2 mg) and Metformin (1000 mg).
  • Glimepiride belongs to the sulfonylurea class, stimulating pancreatic beta cells to increase insulin release and enhancing insulin sensitivity.
  • Metformin is a biguanide that reduces glucose production in the liver and decreases glucose absorption from the intestine. It also improves the body's response to insulin.

• Uses:

  • Primarily used to manage Type 2 Diabetes Mellitus.
  • Helps lower both fasting and post-meal blood glucose levels.
  • Aids in preventing long-term diabetes-related complications such as kidney damage, eye problems, nerve issues, and loss of limbs.

• Dosage and Administration:

  • Typically, one tablet is taken once daily, or as directed by a doctor.
  • It should be taken with meals, preferably during breakfast or the first main meal of the day, to minimize gastrointestinal side effects.
  • Swallow the tablet whole with water; do not crush, chew, or split it.
  • Dosage may vary based on individual blood glucose levels and response to treatment.

• Side Effects:

  • Common: Hypoglycemia (low blood glucose), abdominal pain, nausea, vomiting, diarrhea, headache, and taste disturbances.
  • Serious (rare): Lactic acidosis (symptoms include muscle pain or weakness, dizziness, tiredness, difficulty breathing, stomach pain), and vitamin B12 deficiency with long-term use.

• Precautions:

  • Pregnancy and Breastfeeding: Not recommended during pregnancy and breastfeeding, as components can pass into breast milk.
  • Alcohol: Avoid excessive alcohol consumption as it increases the risk of hypoglycemia and lactic acidosis.
  • Liver/Kidney Impairment: Use with caution in patients with liver disease. Not recommended for those with severe kidney problems due to the risk of lactic acidosis.
  • Allergies: Do not take if allergic to glimepiride, metformin, or any other ingredients.
  • Interactions: May interact with other anti-diabetic agents (increased hypoglycemia risk), thiazide diuretics, and corticosteroids (may increase blood sugar).
  • Regular monitoring of blood sugar, kidney function, and blood cell counts is crucial.

• Storage:

  • Store at room temperature, below 30°C.
  • Protect from direct sunlight and moisture.
  • Keep out of the reach of children.

Here are some frequently asked questions about GLADOR M2 FORTE TABLET (15 TAB) by LUPIN LTD.:

What is GLADOR M2 FORTE TABLET used for?

GLADOR M2 FORTE TABLET is used to treat type 2 diabetes mellitus in adults. It is prescribed when diet and exercise alone are not sufficient to control blood sugar levels, or when blood sugar is not adequately managed by a single antidiabetic medication. It helps to lower blood glucose and prevent long-term diabetes-related complications such as kidney damage, eye problems, and nerve issues.

How does GLADOR M2 FORTE TABLET work?

This medicine contains two active ingredients: Glimepiride and Metformin. Glimepiride works by stimulating the beta cells in the pancreas to release more insulin, which helps to lower blood sugar levels. Metformin works by reducing the amount of glucose produced by the liver, slowing down the absorption of sugar from food in the intestines, and improving the body's sensitivity to insulin, allowing cells to use blood sugar more effectively.

What is the usual dosage of GLADOR M2 FORTE TABLET?

Typically, the starting dose involves one tablet once or twice daily, taken with meals to minimize gastrointestinal side effects. The exact dosage will be determined and adjusted by your doctor based on your blood glucose response and individual needs. It is crucial to swallow the tablet whole with water and not to crush, chew, or split it.

What are the possible side effects of GLADOR M2 FORTE TABLET?

Common side effects may include low blood sugar (hypoglycemia), stomach pain, nausea, diarrhea, vomiting, headache, metallic taste, and dizziness. More serious, but rare, side effects can include lactic acidosis (an accumulation of lactic acid in the body), vitamin B12 deficiency (with long-term use), liver problems, and severe allergic reactions. If you experience persistent or severe side effects, consult your doctor.

Is GLADOR M2 FORTE TABLET safe during pregnancy or breastfeeding?

GLADOR M2 FORTE TABLET is generally not recommended for use during pregnancy as it may harm the unborn baby. Insulin is usually the preferred medication for managing blood sugar levels in pregnant women with diabetes. It is also advised to avoid this medicine while breastfeeding, as its components may pass into breast milk and potentially cause adverse effects in the baby.

Can GLADOR M2 FORTE TABLET be taken with other medications?

GLADOR M2 FORTE TABLET can interact with various other medications. Taking it with other antidiabetic agents (like insulin) may increase the risk of low blood sugar. Certain medications such as thiazide diuretics and corticosteroids can increase blood sugar levels, potentially reducing its effectiveness. It may also interact with some antibiotics, antifungals, HIV/AIDS drugs, antacids, and heart medicines. Always inform your doctor about all medications, supplements, and herbal products you are currently taking to avoid potential drug interactions.

What precautions should be taken while using GLADOR M2 FORTE TABLET?

It is important to avoid alcohol consumption while taking this medication, as it can increase the risk of hypoglycemia (low blood sugar) and lactic acidosis. Regular monitoring of your blood sugar levels is essential. Inform your doctor if you have kidney or liver problems, heart disease, severe infections, or are planning to undergo surgery. This medicine is not for type 1 diabetes or diabetic ketoacidosis. Be aware of the symptoms of hypoglycemia (e.g., sweating, dizziness, shaking) and carry a source of fast-acting sugar (like glucose tablets or fruit juice) with you.

What happens if a dose of GLADOR M2 FORTE TABLET is missed?

If you miss a dose of GLADOR M2 FORTE TABLET, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one, as this can increase the risk of side effects like hypoglycemia.

How should GLADOR M2 FORTE TABLET be stored?

GLADOR M2 FORTE TABLET should be stored in a cool and dry place, away from direct sunlight and moisture. Keep it out of reach and sight of children. Typically, it should be stored at room temperature, between 10ºC to 25ºC or below 30ºC.