Pyloshot Cap

PYLOSHOT CAP by ARISTO PHARMA

Name

• Brand Name: PYLOSHOT CAP

Composition

PYLOSHOT CAP is a nutraceutical formulation. Each capsule contains Lactobacillus reuteri (DSMZ 17648, Pylopass™) 100 mg, equivalent to not less than 10 billion CFU (Colony Forming Units) of Lactobacillus reuteri at the end of shelf life. It also contains bulking agents, capsule shell ingredients, color, glidant, binding agent, and gelling agent.

Uses

PYLOSHOT CAP is designed to support gastrointestinal well-being and maintain microbial balance in the gut. It may help support the natural balance of gut microbiota for digestive comfort and contribute to a healthy stomach environment. This formulation is often used as an adjunct therapy to reduce the side effects associated with Helicobacter pylori (H. pylori) eradication treatment, such as those caused by antibiotic use, and can help alleviate gastrointestinal issues. It is a probiotic food supplement.

Dosage and Administration

For adults, the typical dosage is one capsule twice a day, or as directed by a healthcare professional. The capsule should be swallowed whole with water and not chewed or crushed.

Side Effects

PYLOSHOT CAP is generally well-tolerated. The most common side effect reported for probiotics is mild bloating, which usually subsides with continued use. When used alongside H. pylori eradication therapy, PYLOSHOT has been shown to reduce the incidence of side effects like vomiting, diarrhea, constipation, and headache compared to standard therapy alone. Allergic reactions such as skin rashes, itching, dizziness, coughing, or other respiratory issues, though rare, should be reported to a doctor or pharmacist.

Precautions

PYLOSHOT CAP is suitable for adults. For children under 9 years old, it should only be used under a doctor's prescription. Individuals with a history of allergy to any components of the product should not use it. Caution is advised, and medical supervision is recommended when taken alongside immunosuppressive drugs or chemotherapy.

• Drug Interactions:
  • Antibiotics: Concurrent use may reduce the effectiveness of the probiotic. It's recommended to take PYLOSHOT at least 2 hours before or 4 to 6 hours after antibiotics like tetracycline and quinolone, as calcium, magnesium, and zinc (if present in other Pyloshot formulations or taken concurrently) can affect absorption.
  • Bisphosphonates: Take PYLOSHOT at least 2 hours apart from bisphosphonates (e.g., alendronate).
  • Iron: Zinc (if present in other Pyloshot formulations or taken concurrently) competes with iron for absorption; they should not be taken together or should be taken with food if simultaneous use is necessary.
  • Levothyroxine: Take PYLOSHOT and levothyroxine at least 4 hours apart if the formulation contains calcium carbonate and magnesium. Pregnant or lactating women and individuals with medical conditions should consult a healthcare professional before use.

Storage

Store PYLOSHOT CAP below 25°C, protected from light and moisture, and out of reach of children.

Pyloshot Capsule, manufactured by Aristo Pharma, is a nutraceutical formulation containing a blend of probiotics, paraprobiotics, and minerals designed to support gastrointestinal health. It is primarily known for its role in managing stomach issues, particularly those associated with Helicobacter pylori (H. pylori) infections.

Here are some frequently asked questions about Pyloshot Capsule:

What is Pyloshot Capsule used for?

Pyloshot Capsule is used to address stomach issues, especially gastric infections like those caused by Helicobacter pylori (H. pylori). It helps reduce the side effects associated with antibiotic therapy for H. pylori, manages gastrointestinal problems, and aids in the eradication of the bacteria. The formulation also supports overall gastrointestinal well-being, digestive comfort, gut health, and maintains microbial balance within the digestive system. It can help with gut flora imbalance, digestive discomfort, and stomach acidity.

How does Pyloshot Capsule work?

Pyloshot Capsule contains Lactobacillus reuteri (DSMZ 17648, Pylopass™) as a probiotic and paraprobiotic component, alongside minerals such as calcium carbonate, magnesium oxide, and zinc. The non-viable Lactobacillus reuteri acts as a paraprobiotic, offering beneficial effects through its bioactive compounds and interacting with the host's immune system, which contributes to its stability and safety. The minerals included function as antacids, assist in maintaining electrolyte balance, support digestive enzyme function, and help regulate the stomach's acid-base balance. This combination helps alleviate symptoms and improve digestive health.

What is the usual dosage for Pyloshot Capsule?

The typical dosage is one capsule twice a day, or two capsules daily (one in the morning and one in the evening), for 14 days, or as directed by a healthcare professional. The capsules should be swallowed whole with water and should not be chewed or crushed.

What are the possible side effects of Pyloshot Capsule?

Pyloshot Capsule is generally well-tolerated. The most common side effect reported is mild bloating, which usually subsides with continued use. In studies, when Pyloshot was used alongside standard four-drug therapy for H. pylori, it was associated with a lower incidence of common side effects like vomiting, diarrhea, constipation, and headache compared to the standard therapy alone. If allergic reactions such as skin rashes, itching, dizziness, coughing, or other respiratory issues occur, discontinue use and inform your doctor or pharmacist immediately.

Is Pyloshot Capsule safe during pregnancy or breastfeeding?

There is insufficient information regarding the use of Pyloshot Capsule during pregnancy and breastfeeding, and therefore, it should be avoided unless specifically advised by a doctor. Pregnant or lactating women, or those with underlying medical conditions, should consult a healthcare professional before using this product.

Can Pyloshot Capsule be taken with other medications?

Caution is advised when taking Pyloshot Capsule with certain medications.

• Antibiotics: Concurrent use may reduce the effectiveness of probiotics. It is recommended to take Pyloshot 2 hours before or 4 to 6 hours after tetracycline and quinolone antibiotics.
• Bisphosphonates (e.g., alendronate): Minerals like calcium and magnesium can decrease the absorption of bisphosphonates. Pyloshot should be taken at least 2 hours apart from these medications.
• Iron: Zinc, present in Pyloshot, competes with iron for absorption, so they should not be taken together.
• Levothyroxine: Supplements containing calcium carbonate and magnesium can reduce levothyroxine absorption. It is recommended to take Pyloshot and levothyroxine at least 4 hours apart.
• Immunosuppressive drugs or chemotherapy: Use Pyloshot with caution and under the supervision of a doctor. Always inform your doctor or pharmacist about all medications and supplements you are taking.

What precautions should be taken while using Pyloshot Capsule?

Pyloshot Capsule is suitable for adults and children over 9 years old. For children under 9 years of age, it should only be used with a doctor's prescription. Patients with specific conditions such as immune system deficiencies, short bowel syndrome, copper deficiency, sideroblastic anemia, neutropenia, high blood calcium levels, kidney failure, fever, or a history of drug or food allergies should inform their doctor before using this product. Do not exceed the recommended daily dosage.

What happens if a dose of Pyloshot Capsule is missed?

If you miss a dose of Pyloshot Capsule, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose to make up for a missed one.

How should Pyloshot Capsule be stored?

Pyloshot Capsule should be stored at a temperature below 25°C. Keep the capsules away from light, moisture, and out of the reach of children.