Voglistar Plus 0.2

VOGLISTAR PLUS 0.2

VOGLISTAR PLUS 0.2, manufactured by Mankind Pharma Ltd., is a combination medication used to manage blood sugar levels in individuals with type 2 diabetes mellitus.

• Composition: Each tablet contains Voglibose (0.2 mg) and Metformin (500 mg).

  • Voglibose is an alpha-glucosidase inhibitor that delays the digestion and absorption of carbohydrates in the small intestine, thus preventing post-meal blood sugar spikes.
  • Metformin, a biguanide, primarily works by decreasing glucose production in the liver and improving insulin sensitivity in the body's cells, allowing for more effective glucose utilization.

• Uses: VOGLISTAR PLUS 0.2 is prescribed for the treatment of type 2 diabetes mellitus, particularly when diet and exercise alone, or therapy with single agents, do not achieve adequate glycemic control. It helps in lowering post-prandial blood glucose levels, controlling blood sugar after meals, and improving insulin sensitivity.

• Dosage and Administration: This medicine is typically taken orally, usually before or with the first bite of each main meal, or as prescribed by a doctor. It is important to follow the prescribed dosage and schedule consistently. Do not exceed the recommended dose.

• Side Effects: Common side effects may include nausea, vomiting, diarrhea, abdominal pain, flatulence (gas), loss of appetite, heartburn, metallic taste, and headache. Hypoglycemia (low blood sugar) can occur, especially when used with other antidiabetic drugs, alcohol, or if meals are missed. Serious but less common side effects include allergic reactions, liver problems, changes in blood cell counts, muscle pain, weakness, dizziness, and a rare condition called lactic acidosis.

• Precautions:

  • Avoid excessive alcohol consumption, as it can increase the risk of lactic acidosis.
  • Not recommended for pregnant or breastfeeding women, or children under 18 years, due to insufficient safety data.
  • Caution is advised in elderly patients.
  • Inform your doctor about pre-existing conditions such as severe kidney or liver problems, heart disease, acute metabolic acidosis, or severe infections.
  • Regular monitoring of blood sugar levels is essential. Carry a fast-acting sugar source for hypoglycemic episodes.

• Storage: Store in a cool and dry place, below 30°C, away from direct sunlight and out of reach of children.

VOGLISTAR PLUS 0.2 by MANKIND PHARMA LTD is a combination medication used for the management of Type 2 Diabetes Mellitus. It contains two active ingredients: Voglibose and Metformin.

What is VOGLISTAR PLUS 0.2 used for?

VOGLISTAR PLUS 0.2 is used to control high blood sugar levels in adults with Type 2 Diabetes Mellitus, especially when diet and exercise alone are not sufficient. It helps lower post-meal blood glucose levels, improves insulin sensitivity, and can be used in combination with other diabetes medications. It can also reduce the risk of diabetic complications affecting the heart, kidneys, and eyes.

How does VOGLISTAR PLUS 0.2 work?

This medicine combines Voglibose and Metformin, each working through different mechanisms to control blood sugar. Voglibose, an alpha-glucosidase inhibitor, works in the small intestine to slow down the digestion and absorption of carbohydrates, which prevents sharp spikes in blood sugar levels after meals. Metformin, a biguanide, primarily reduces glucose production in the liver and improves the body's sensitivity to insulin, helping cells utilize insulin more effectively. It also has a modest effect on reducing intestinal glucose absorption.

What is the usual dosage for VOGLISTAR PLUS 0.2?

VOGLISTAR PLUS 0.2 should be taken exactly as prescribed by your doctor, typically just before or with the first bite of your main meals. The usual dosage can be one tablet, taken three times daily, but this may vary based on your health condition and response to the medicine. It's crucial to follow the prescribed dosage and not to exceed it without consulting your doctor.

What are the possible side effects of VOGLISTAR PLUS 0.2?

Common side effects include nausea, vomiting, diarrhea, abdominal pain, flatulence (gas), loss of appetite, heartburn, and a metallic taste in the mouth. Hypoglycemia (low blood sugar) can also occur, especially when combined with other antidiabetic drugs, alcohol, or if meals are missed. Less common but more serious side effects can include allergic reactions, liver problems, changes in blood cell counts, muscle pain, weakness, dizziness, and lactic acidosis.

Is VOGLISTAR PLUS 0.2 safe during pregnancy or breastfeeding?

VOGLISTAR PLUS 0.2 is generally not recommended during pregnancy due to a lack of safety data and potential harmful effects on the developing baby observed in animal studies. Similarly, it is probably unsafe during breastfeeding as limited human data suggests the drug may pass into breast milk and harm the baby. It is crucial to consult your doctor if you are pregnant or breastfeeding before taking this medicine.

Can VOGLISTAR PLUS 0.2 be taken with other medications?

It is important to inform your doctor about all other medications, including prescription drugs, over-the-counter medicines, and herbal supplements, as they may interact with VOGLISTAR PLUS 0.2. Some medicines, such as carbonic anhydrase inhibitors (e.g., topiramate, zonisamide), cationic medicines (e.g., amiloride, digoxin), and certain other medications (e.g., phenothiazines, thyroid products), can interact with VOGLISTAR PLUS 0.2, potentially increasing the risk of side effects like lactic acidosis or reducing its effectiveness.

What precautions should be taken with VOGLISTAR PLUS 0.2?

Avoid excessive alcohol consumption while taking VOGLISTAR PLUS 0.2, as it can increase the risk of hypoglycemia and a serious condition called lactic acidosis. It is not recommended for individuals with severe kidney problems, liver disease, acute metabolic acidosis (including diabetic ketoacidosis), severe infections, or a history of heart failure. Regular monitoring of blood sugar levels is essential, and blood cell counts and liver function may also need to be checked. If you experience symptoms of lactic acidosis (deep/rapid breathing, persistent nausea, vomiting, or stomach pain), seek immediate medical attention.

What happens if a dose of VOGLISTAR PLUS 0.2 is missed?

If you miss a dose, take it as soon as you remember. However, if it's almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to compensate for a missed one.

How should VOGLISTAR PLUS 0.2 be stored?

VOGLISTAR PLUS 0.2 should be stored in a cool and dry place, away from direct sunlight, and kept out of sight and reach of children. The recommended storage temperature is typically between 10ºC and 25ºC or below 30ºC.