Esiflo 125 Inh

ESIFLO 125 INH by Lupin Ltd. is a combination medication used for the long-term management of respiratory conditions.

Name

• Brand Name: ESIFLO 125 INH, ESIFLO 125 HFA Transhaler, ESIFLO 125 Transhaler.

Composition

• Active Ingredients: Salmeterol (25 mcg) and Fluticasone Propionate (125 mcg). Salmeterol is a long-acting beta-2 adrenergic agonist (LABA), and Fluticasone Propionate is a corticosteroid.

Uses

ESIFLO 125 INH is prescribed for the maintenance treatment of:

• Asthma: To relieve and prevent symptoms like difficulty breathing, wheezing, shortness of breath, coughing, and chest tightness.
• Chronic Obstructive Pulmonary Disease (COPD): Including chronic bronchitis and emphysema, to control and minimize symptoms and reduce exacerbations. It is not for immediate relief of sudden breathing problems or acute asthma attacks.

Dosage and Administration

• This medicine is for inhalation only and should not be swallowed.
• It is typically administered as one or two inhalations twice daily, as directed by a physician.
• It should be taken at the same time each day for consistent effectiveness.
• Rinse your mouth with water and spit it out after each use to help prevent fungal infections.
• The first dose should ideally be taken under medical supervision.

Side Effects

Common Side Effects:

• Nausea, vomiting, headache, sore throat, cough, hoarseness of voice, respiratory tract infection.
• Fungal infections in the mouth (oral thrush).
• Musculoskeletal (bone, muscle, or joint) pain, increased heart rate.

Serious Side Effects (rare):

• Paradoxical bronchospasm (wheezing immediately after using the inhaler).
• Allergic reactions (swelling of face, lips, tongue, or throat).
• Hyperglycemia (increased blood sugar levels), Hypokalemia (low potassium levels).
• Glaucoma, cataracts, osteoporosis, Cushing's syndrome.

Precautions

• Inform your doctor if you have diabetes, thyroid disorders, high blood pressure, heart disease, liver problems, or active infections (fungal, bacterial, viral, tuberculosis).
• Use with caution in patients with seizure disorders.
• May interact with certain antifungals (e.g., ketoconazole), antivirals (e.g., ritonavir), and some blood pressure-lowering medicines (e.g., propranolol).
• Pregnant or breastfeeding individuals should consult their doctor.
• Not recommended for children under four years of age.

Storage

• Store below 30°C, in a cool and dry place, away from heat and direct light.
• Keep out of the reach of children and pets.

ESIFLO 125 INH by LUPIN LTD (also known as Esiflo 125 Transhaler or Esiflo 125 HFA Transhaler) is an inhalation medicine used for managing respiratory conditions.

What is ESIFLO 125 INH used for?

ESIFLO 125 INH is primarily used for the long-term management and control of symptoms associated with obstructive airway diseases such as asthma and Chronic Obstructive Pulmonary Disease (COPD), which includes chronic bronchitis and emphysema. It helps to relieve symptoms like wheezing, shortness of breath, coughing, and chest tightness. It is not intended for immediate relief of sudden asthma attacks, for which a quick-relief inhaler should be used.

How does ESIFLO 125 INH work?

ESIFLO 125 INH is a combination medication containing two active ingredients: Salmeterol and Fluticasone Propionate. Salmeterol is a long-acting bronchodilator that works by relaxing the muscles in the airways, which helps to widen them and make breathing easier. Fluticasone Propionate is a corticosteroid that reduces inflammation and swelling in the airways by blocking the release of certain chemical messengers that cause inflammation. Together, these two components improve lung function and make breathing easier.

What is the usual dosage for ESIFLO 125 INH?

The typical dosage of ESIFLO 125 INH is usually one or two inhalations twice daily. However, the exact dosage is determined by your doctor based on the severity of your condition and your individual response to the medication. It should be taken at the same time each day for consistent management.

What are the possible side effects of ESIFLO 125 INH?

Common side effects can include a sore throat, hoarseness of voice, cough, headache, and oral thrush (a fungal infection in the mouth). Other possible side effects may include respiratory tract infection, nausea, vomiting, musculoskeletal pain, and an increased heart rate. To help prevent oral thrush, it is important to rinse your mouth thoroughly with water and spit it out after each use of the inhaler.

Is ESIFLO 125 INH safe during pregnancy or breastfeeding?

The use of ESIFLO 125 INH during pregnancy is considered to have a moderate effect, and during breastfeeding, it has a mild effect. There is limited data on its effects during breastfeeding. It should only be used if deemed necessary by a medical professional after consulting your doctor.

Can ESIFLO 125 INH be taken with other medications?

ESIFLO 125 INH can interact with certain medications. For example, some antifungals (like ketoconazole) and antiviral medicines (like ritonavir) may increase the levels of fluticasone in your body, potentially leading to increased side effects. Certain blood pressure-lowering medicines (e.g., propranolol) can cause narrowing of the airways. Diuretics (non-potassium-sparing) may increase the risk of low potassium levels. It's crucial to inform your doctor about all ongoing medications, including herbal supplements, to avoid potential interactions.

What precautions should be taken while using ESIFLO 125 INH?

Do not use ESIFLO 125 INH to treat sudden asthma attacks; a quick-relief inhaler is needed for acute symptoms. Always rinse your mouth with water and spit it out after each inhalation to help prevent fungal infections in the mouth and throat. If you are diabetic, monitor your blood sugar levels regularly, as this medicine may cause an increase in blood sugar. Special caution is advised for patients with cardiovascular disorders, seizure disorders, liver or kidney disease, low potassium levels (hypokalemia), or active infections (fungal, bacterial, viral, or tuberculosis). ESIFLO 125 INH is not recommended for children under four years of age. Do not stop using the medicine without consulting your doctor, as discontinuing it abruptly can worsen your symptoms.

What happens if a dose of ESIFLO 125 INH is missed?

If you miss a dose of ESIFLO 125 INH, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

How should ESIFLO 125 INH be stored?

ESIFLO 125 INH should be stored in a cool and dry place, away from direct sunlight. It should be kept out of the sight and reach of children. The recommended storage temperature is typically between 10ºC to 25ºC or below 30ºC.