Istavel D 10/100 Mg Tablet (15 Tab)

ISTAVEL D 10/100 MG TABLET

ISTAVEL D 10/100 MG TABLET is a medication manufactured by SUN PHARMA LABORATORIES LTD., primarily used in the management of type 2 diabetes mellitus.

• Name:
  • Brand Name: ISTAVEL D 10/100 Tablet
• Composition:
  • The tablet contains a combination of two active ingredients: Dapagliflozin (10 mg) and Sitagliptin (100 mg).
  • Dapagliflozin is a sodium-glucose co-transporter 2 (SGLT-2) inhibitor, which increases glucose excretion through urine. Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor, which works by increasing insulin levels and decreasing glucagon levels to reduce glucose production by the liver.
• Uses:
  • It is prescribed for the management of type 2 diabetes mellitus in adults, especially when blood sugar levels are not adequately controlled by metformin alone, or in conjunction with diet and exercise.
  • It helps control blood sugar levels, reduces the risk of diabetes-related complications, and may also aid in weight loss and blood pressure control. It can also be used to treat chronic kidney disease in adults with reduced kidney function.
• Dosage and Administration:
  • ISTAVEL D 10/100 MG TABLET should be taken orally, exactly as recommended by your doctor. It can be taken with or without food, preferably at the same time each day for consistent results. Do not stop the medication abruptly without consulting your doctor.
• Side Effects:
  • Common side effects include urinary tract infections, nasal congestion, sore throat, upper respiratory tract infections, and headache. Some individuals may experience fungal infections in the genital area. Serious side effects can include acute pancreatitis and severe allergic reactions.
• Precautions:
  • Caution is advised in patients with kidney or liver disorders, heart failure, and those taking diuretics. It is not recommended for use in children below 18 years of age, or in individuals with type 1 diabetes or diabetic ketoacidosis. Pregnant or breastfeeding women should consult their doctor before use. Avoid excessive alcohol consumption as it may increase the risk of side effects.
• Storage:
  • Store ISTAVEL D 10/100 MG TABLET in a cool and dry place below 30°C, away from direct sunlight and moisture. Keep out of reach of children and pets.

What is ISTAVEL D 10/100 MG TABLET used for?

ISTAVEL D 10/100 MG TABLET is primarily used for the management of type 2 diabetes mellitus in adults, especially when blood sugar levels are not adequately controlled by metformin alone. It aids in improving blood sugar control and can also contribute to blood pressure control, weight loss, cardiovascular risk reduction, and the treatment of chronic kidney disease.

How does ISTAVEL D 10/100 MG TABLET work?

This medicine contains two active ingredients: Dapagliflozin and Sitagliptin. Dapagliflozin, an SGLT2 inhibitor, works by increasing the excretion of glucose (sugar) from the body through urine, thereby lowering blood sugar levels. Sitagliptin, a DPP-4 inhibitor, increases the levels of natural substances called incretins in the body, which, in turn, increase insulin levels after a meal and decrease the amount of glucose produced by the liver.

What is the usual dosage for ISTAVEL D 10/100 MG TABLET?

The dosage of ISTAVEL D 10/100 MG TABLET should be taken exactly as prescribed by your doctor. It is typically taken once daily, with or without food. For optimal benefits, it's recommended to take it consistently at the same time each day. Do not exceed the recommended dose.

What are the possible side effects of ISTAVEL D 10/100 MG TABLET?

Common side effects may include urinary tract infections (UTIs), nasal congestion, sore throat, upper respiratory tract infections, headache, dizziness, nausea, vomiting, flatulence, constipation, stomach pain, diarrhea, dry mouth, frequent urination, and fungal infections in the genital area. More serious but less common side effects can include acute pancreatitis (severe stomach pain) and serious allergic reactions (rash, hives, swelling of the face/tongue/throat).

Is ISTAVEL D 10/100 MG TABLET safe during pregnancy or breastfeeding?

There is limited information regarding the effect of ISTAVEL D 10/100 MG TABLET in pregnant women, and therefore, it should not be used during pregnancy. Similarly, it is not recommended for use in breastfeeding women as it is unknown if the medicine passes into human breast milk. Always inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

Can ISTAVEL D 10/100 MG TABLET be taken with other medications?

It is crucial to inform your doctor about all other medicines, herbal products, or supplements you are currently taking or plan to take to avoid possible interactions. Particular care should be taken if you are also taking diuretics (water pills) as this can increase the risk of dehydration and low blood pressure. Combining it with insulin or sulfonylureas may cause extremely low blood sugar levels. Interactions may also occur with certain antifungal medications (e.g., ketoconazole), antiviral agents (e.g., ritonavir), antibiotics (e.g., clarithromycin), cardiac glycosides (e.g., digoxin), corticosteroids, and estrogens.

What precautions should be taken while using ISTAVEL D 10/100 MG TABLET?

This medicine is not for individuals with type 1 diabetes or diabetic ketoacidosis. Exercise caution if you have kidney or liver problems, heart failure, or a history of urinary tract infections. It's advisable to avoid excessive alcohol consumption. Inform your doctor if you are dehydrated or have restricted food intake. Be vigilant for symptoms of acute pancreatitis or allergic reactions. Maintaining good hygiene is important to prevent genital fungal infections, and drinking plenty of fluids can help prevent dehydration. Also, inform your doctor if you are scheduled for surgery.

What happens if a dose of ISTAVEL D 10/100 MG TABLET is missed?

If you miss a dose of ISTAVEL D 10/100 MG TABLET, take it as soon as you remember. However, if it's almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to compensate for the missed one.

How should ISTAVEL D 10/100 MG TABLET be stored?

Store ISTAVEL D 10/100 MG TABLET in a cool and dry place, preferably below 30°C, away from direct sunlight and moisture. Ensure it is kept out of the reach of children and pets.