Amazeo Od 400 Mg Tablet (10 Tab)

AMAZEO OD 400 MG TABLET (10 TAB)

AMAZEO OD 400 MG TABLET, manufactured by Torrent Pharmaceuticals Ltd., is an atypical antipsychotic medication primarily used to manage certain mental health conditions.

Composition

Each tablet contains Amisulpride 400mg as the active ingredient.

Uses

AMAZEO OD 400 MG TABLET is prescribed for:

• Schizophrenia: It treats both positive symptoms (e.g., delusions, hallucinations, thought disorders) and negative symptoms (e.g., blunted affect, emotional and social withdrawal, lack of interest) by helping to restore chemical imbalances in the brain.
• Bipolar disorder: It may also be used to control mania, aggression, impulsive behavior, and irritability associated with bipolar disorder.
• Postoperative nausea/vomiting: It has anti-emetic properties and can be used to prevent nausea and vomiting that may occur after surgery.

Dosage and Administration

AMAZEO OD 400 MG TABLET is for oral administration and can be taken with or without food. For doses above 300 mg, such as 400 mg, it may be advised to take half the dose in the morning and half in the evening. It is important to take the medicine at the same time each day to maintain a consistent level in the body. The tablets should be swallowed whole and not crushed, chewed, or broken. Do not stop taking this medication abruptly without consulting your doctor, as it can worsen symptoms or cause withdrawal effects.

Side Effects

Common Side Effects:

• Nausea, vomiting, dry mouth, constipation
• Weight gain, increased blood sugar, increased cholesterol and triglycerides
• Drowsiness, sleepiness, dizziness, blurred vision, insomnia
• Decreased blood pressure (especially upon changing positions)
• Dystonia (involuntary muscle contractions), akathisia (inability to stay still), parkinsonism (trembling, muscle stiffness)
• Increased prolactin level in blood, unusual production of breast milk, breast pain, breast enlargement (gynecomastia in men), absence of menstrual period, erectile dysfunction
• Anxiety, agitation

Serious Side Effects (Consult a doctor immediately if experienced):

• Neuroleptic Malignant Syndrome (characterized by high temperature, stiff muscles, fast heartbeat, confusion)
• Allergic reactions (swelling of face, lips, tongue, throat, difficulty breathing, rash)
• Fits or seizures
• Heart rhythm problems (prolonged QT interval)

Precautions

• Contraindications: Do not use if under 15 years of age, allergic to Amisulpride, have breast cancer or a prolactin-dependent tumor, pheochromocytoma (adrenal gland tumor), or a pituitary tumor. It is also not recommended for breastfeeding women.
• Pregnancy: Consult your doctor if pregnant or planning a pregnancy, as it may be unsafe during pregnancy.
• Elderly Patients: Use with caution in patients over 65 years due to increased risk of hypotension or sedation.
• Medical Conditions: Inform your doctor if you have kidney disease (dose adjustment may be needed), liver disease (use with caution in moderate to severe impairment), diabetes, Parkinson's disease (may worsen symptoms), epilepsy/seizures, unusual heart rate, slow heartbeat, low potassium levels, or a history of blood clots, heart problems, or stroke.
• Interactions: Inform your doctor about all other medications you are taking, especially levodopa, medicines for heart rhythm disorders, diltiazem, cisapride, pregabalin, tramadol, quinidine, halofantrine, erythromycin, pimozide, haloperidol, guanfacine, CNS depressants, clonidine, calcium channel blockers, tricyclic antidepressants, digoxin, lithium, antihypertensives, barbiturates, and benzodiazepines.
• Alcohol: Avoid alcohol consumption as it can increase drowsiness and other side effects.
• Driving/Operating Machinery: This medicine can cause dizziness, drowsiness, and blurred vision. Avoid driving or operating heavy machinery until you know how it affects you.
• Orthostatic Hypotension: To reduce the risk of dizziness or fainting, rise slowly when getting up from a sitting or lying position.

Storage

Store below 30°C in a cool and dry place. Keep out of reach of children.

Here are frequently asked questions about AMAZEO OD 400 MG TABLET:

What is Amazeo OD 400 MG Tablet used for?

Amazeo OD 400 MG Tablet is primarily used to treat schizophrenia, a mental disorder characterized by hallucinations, delusions, and abnormal thinking and behavior. It is also prescribed for bipolar disorder and other psychotic illnesses. In some cases, it may be used for postoperative nausea and vomiting.

How does Amazeo OD 400 MG Tablet work?

This medicine contains Amisulpride, which is an atypical antipsychotic. It works by blocking specific dopamine receptors (D2 and D3) in the brain, helping to restore the balance of certain natural chemical messengers. This action improves thoughts, feelings, and behavior, thereby managing the symptoms of schizophrenia.

What is the usual dosage for Amazeo OD 400 MG Tablet?

The dosage and duration of treatment are determined by your doctor based on your individual condition. It is generally advised to take the tablet with or without food, preferably before bedtime, at the same time each day to maintain a consistent level of medicine in your body. Doses exceeding 300 mg might sometimes be taken as half in the morning and half in the evening. The tablet should be swallowed whole and not chewed, crushed, or broken.

What are the possible side effects of Amazeo OD 400 MG Tablet?

Common side effects can include nausea, vomiting, dry mouth, constipation, blurred vision, insomnia (difficulty sleeping), dizziness, sleepiness, and erectile dysfunction. It may also lead to weight gain, increased blood sugar, cholesterol levels, and a sudden drop in blood pressure when changing positions. More serious but less common side effects can include involuntary muscle contractions (dystonia, akathisia), increased prolactin levels in the blood, and rarely, neuroleptic malignant syndrome or seizures.

Is Amazeo OD 400 MG Tablet safe during pregnancy or breastfeeding?

Amazeo OD 400 MG Tablet is generally not recommended for use during pregnancy or in women planning for pregnancy, as animal studies have shown harmful effects on the developing baby, and human data is limited. It is also considered probably unsafe and not recommended during breastfeeding, as the drug may pass into breast milk and harm the baby. Always consult your doctor if you are pregnant, planning to conceive, or breastfeeding.

Can Amazeo OD 400 MG Tablet be taken with other medications?

You should inform your doctor about all medications you are currently taking, including over-the-counter drugs and herbal supplements. It is not recommended to take Amazeo OD 400 MG Tablet with levodopa (used for Parkinson's disease) or certain medicines for heart rhythm disorders, as their effects can be opposite or interactions may occur. Alcohol consumption should be avoided or limited as it can worsen side effects like drowsiness.

What precautions should be taken with Amazeo OD 400 MG Tablet?

This medicine should be used with caution in elderly patients and those with kidney disease, liver problems, diabetes, Parkinson's disease, heart conditions (especially those predisposing to QT interval prolongation), a history of seizures, or blood clots. It is not recommended for individuals under 15 or 18 years of age, or those with breast cancer, prolactin-dependent tumors, pheochromocytoma, or pituitary tumors. Due to potential dizziness and sleepiness, avoid driving or operating heavy machinery until you know how the medicine affects you.

What happens if a dose of Amazeo OD 400 MG Tablet is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up. It is important not to suddenly stop this medication without consulting your doctor, as it can worsen your symptoms or cause withdrawal effects.

How should Amazeo OD 400 MG Tablet be stored?

Amazeo OD 400 MG Tablet should be stored in a cool and dry place, and kept out of the reach of children.