Rowasa 500 Mg Sachet

ROWASA 500 MG SACHET

ROWASA 500 MG SACHET, manufactured by Abbott India Limited, is a medicine used primarily for managing inflammatory bowel diseases.

• Name: ROWASA 500 MG SACHET. It is also referred to as Rowasa 500 mg Pellets.
• Composition: Each sachet contains 500 mg of Mesalazine (also known as Mesalamine), which is an aminosalicylate.
• Uses:
  • Ulcerative Colitis: It is prescribed for the management of mild to moderate ulcerative colitis, a chronic inflammatory bowel disease affecting the large intestine and rectum. It helps alleviate symptoms such as diarrhea, rectal bleeding, and abdominal pain, and is used to maintain remission and prevent relapse of symptoms.
  • Crohn's Disease: It is also used to control symptoms in Crohn's disease, another chronic inflammatory bowel disease that can affect any part of the gastrointestinal tract.
• Dosage and Administration:
  • Take the sachet orally, as directed by your doctor.
  • Swallow the pellets whole without chewing or crushing them to ensure controlled release.
  • It can be taken before meals, and the granules can be washed down with water or orange juice, or mixed with yogurt and consumed immediately.
  • Do not exceed the recommended dose.
• Side Effects:
  • Common: Headache, dizziness, nausea, vomiting, abdominal pain, diarrhea, flatulence, and rash. Joint or leg pain has also been reported.
  • Serious: Rare but serious side effects can include worsening stomach pain or bloody diarrhea, severe skin reactions (like Stevens-Johnson syndrome), and blood disorders.
• Precautions:
  • Allergies: Not recommended for individuals with known allergies to Mesalazine, salicylates, or sulphasalazine.
  • Pregnancy and Breastfeeding: Use with caution and only if clearly necessary; consult a doctor.
  • Organ Impairment: Use with caution in patients with liver or kidney problems, with monitoring of organ function. Avoid if severe kidney impairment.
  • Other Conditions: Caution is advised in patients with active peptic ulcer disease or lung problems like asthma.
  • Drug Interactions: May interact with immunosuppressants (e.g., azathioprine), anticoagulants (e.g., warfarin), NSAIDs, and antacids. Inform your doctor about all medications you are taking.
  • Do not stop the medication suddenly without consulting your doctor.
• Storage: Store in a cool, dry place below 30°C, away from direct sunlight and moisture. Keep out of reach of children. Use before the expiry date.

Here are some frequently asked questions about ROWASA 500 MG SACHET (Mesalazine), along with concise answers:

What is ROWASA 500 MG SACHET used for?

ROWASA 500 MG SACHET is primarily used to treat mild to moderate ulcerative colitis and Crohn's disease, which are chronic inflammatory bowel diseases. It helps reduce inflammation, alleviate symptoms such as diarrhea, rectal bleeding, and abdominal pain, and can also help prevent flare-ups of ulcerative colitis.

How does ROWASA 500 MG SACHET work?

ROWASA 500 MG SACHET contains Mesalazine, an anti-inflammatory drug. It works by inhibiting the production of certain chemical substances, such as prostaglandins and leukotrienes, that cause pain and swelling in the intestines. This action reduces inflammation, ulceration, and associated symptoms in the colon.

What is the usual dosage for ROWASA 500 MG SACHET?

The exact dose and duration of ROWASA 500 MG SACHET will be determined by your doctor based on your age, body weight, and medical condition. It is typically advised to take it once daily, preferably before meals. The contents of the sachet can be emptied directly onto the tongue and washed down with water or orange juice, or mixed with yogurt and consumed immediately without chewing. Do not exceed the recommended dose.

What are the possible side effects of ROWASA 500 MG SACHET?

Common side effects may include headache, dizziness, nausea, vomiting, abdominal pain, diarrhea, and flatulence (gas). More severe but rare side effects can include severe skin reactions like Stevens-Johnson syndrome or toxic epidermal necrolysis, kidney impairment, and worsening of symptoms. If side effects persist or worsen, or if you experience severe symptoms like stomach pain, cramps, severe headache, fever, or rash, consult your doctor immediately.

Is ROWASA 500 MG SACHET safe during pregnancy or breastfeeding?

ROWASA 500 MG SACHET should be used with caution during pregnancy and breastfeeding, and only if clearly necessary. If you are pregnant or breastfeeding, inform your doctor before taking this medicine, as they will weigh the potential risks and benefits. For breastfeeding mothers, monitoring the infant for diarrhea is advised.

Can ROWASA 500 MG SACHET be taken with other medications?

Mesalazine, the active ingredient in ROWASA, can interact with certain medications. Inform your doctor about all medicines you are taking, including over-the-counter drugs, vitamins, and herbal supplements. Specific interactions include:

• Immunosuppressants like azathioprine and 6-mercaptopurine: Increased risk of blood disorders.
• Anticoagulants like warfarin: The effect of warfarin might be enhanced, increasing the risk of bleeding.
• Antacids containing magnesium or aluminum: May decrease the absorption of mesalazine, making it less effective.
• Non-steroidal anti-inflammatory drugs (NSAIDs): May increase the risk of kidney impairment.

What precautions should be taken with ROWASA 500 MG SACHET?

Avoid taking ROWASA 500 MG SACHET if you have severe kidney failure or bleeding disorders. Use with caution if you have mild to moderate kidney or liver problems, lung problems (like asthma), or an active peptic ulcer. Elderly patients should use it with caution. If you develop any skin reactions, stomach pain, cramps, severe headache, fever, or rash, stop taking the medicine and consult your doctor. Do not stop taking the medicine without consulting your doctor, as symptoms may return.

What happens if a dose of ROWASA 500 MG SACHET is missed?

If you miss a dose, take it as soon as you remember. However, if it's almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

How should ROWASA 500 MG SACHET be stored?

Store ROWASA 500 MG SACHET in a cool, dry place, away from direct sunlight and moisture. The temperature should be below 30°C, ideally between 10ºC to 25ºC. Keep it out of reach and sight of children.