Azee 100 Dt

AZEE 100 DT is an antibiotic medication manufactured by Cipla Ltd. designed primarily for treating various bacterial infections in children.

Name

• Brand Name: AZEE 100 DT
• Common Name: Azithromycin (dispersible tablet)

Composition

• Each dispersible tablet contains Azithromycin 100 mg.
• AZEE 100 DT belongs to the macrolide class of antibiotics. It works by inhibiting bacterial protein synthesis, thereby stopping bacterial growth and multiplication.

Uses AZEE 100 DT is prescribed for a wide range of bacterial infections, including:

• Respiratory tract infections (e.g., pneumonia, bronchitis, tonsillitis, pharyngitis, sinusitis).
• Ear infections (acute otitis media).
• Skin and soft tissue infections.
• Gastrointestinal tract infections.
• Certain sexually transmitted infections (e.g., chlamydia, gonorrhea).
• It is not effective against viral or fungal infections.

Dosage and Administration

• The typical dosage is usually once daily, preferably in the morning; however, for conditions like typhoid, it may be twice a day.
• Dissolve the tablet in a small amount of water (e.g., 5 ml boiled and cooled water) before administration.
• It can be taken with or without food, though taking it with food is often recommended for children to minimize stomach upset.
• The exact dose and duration depend on the infection type, severity, and the patient's age and weight, as determined by a healthcare professional.
• It is crucial to complete the entire prescribed course to ensure complete eradication of bacteria and prevent antibiotic resistance. If a child vomits within 30 minutes of taking the dose, it should be readministered.

Side Effects

• Common: Diarrhea, nausea, abdominal pain, vomiting, headache, skin rash, altered taste sensation, and indigestion. These are generally mild and temporary.
• Serious (less common): Persistent vomiting, severe gastrointestinal infections, kidney damage, dizziness, fits, or allergic reactions (rash, facial swelling, breathing difficulties). Liver issues such as hepatitis have also been reported.

Precautions

• AZEE 100 DT is contraindicated in individuals with known hypersensitivity to azithromycin, erythromycin, or other macrolide antibiotics.
• Caution is advised in patients with liver, kidney, or heart problems, and those with Myasthenia Gravis.
• Antacids containing aluminum or magnesium may reduce azithromycin absorption. Significant interactions can occur with medications like warfarin, amiodarone, sotalol, and certain HIV medications, among others.
• Patients should avoid excessive sun exposure due to increased risk of sunburn. It may cause dizziness, affecting the ability to drive or operate machinery.

Storage

• Store in a cool, dry place below 30°C, away from direct light and dampness.
• Keep out of sight and reach of children and pets.
• Do not use after the expiry date.

What is AZEE 100 DT used for?

AZEE 100 DT is an antibiotic primarily used for managing various bacterial infections in children. These include infections of the respiratory tract (such as pneumonia, bronchitis, tonsillitis, pharyngitis, and sinusitis), ear infections (acute otitis media), skin and soft tissue infections, and certain sexually transmitted diseases like chlamydia. It is effective only against bacterial infections and does not work for viral or fungal infections.

How does AZEE 100 DT work?

AZEE 100 DT contains azithromycin, which is a macrolide antibiotic. It works by inhibiting the growth and multiplication of bacteria. Azithromycin binds to the 50S subunit of bacterial ribosomes, which are crucial for the bacteria to synthesize proteins. By inhibiting protein synthesis, it leads to the eventual death of the bacteria.

What is the usual dosage of AZEE 100 DT?

The dosage of AZEE 100 DT is determined by a doctor based on the type and severity of the infection, as well as the child's age and body weight. It is usually given once a day, preferably in the morning. For conditions like typhoid, it might be prescribed twice a day. The tablet should be dissolved in 5 ml (a teaspoonful) of boiled and cooled water before administration, and the child should swallow the dispersed tablet completely. It's crucial to follow the prescribed dosage and complete the full course of treatment, even if symptoms improve, to prevent the bacteria from multiplying again or becoming resistant.

What are the possible side effects of AZEE 100 DT?

Common side effects of AZEE 100 DT include diarrhea, nausea, abdominal pain, vomiting, and headache. These side effects are usually mild and temporary, often resolving as the body adjusts to the medicine. In some cases, a skin rash may occur. More serious, though rare, side effects can include persistent vomiting, kidney damage, severe allergic reactions (like rashes, itching, swelling, shortness of breath), or severe gastrointestinal infections. If any serious or worsening side effects are observed, medical attention should be sought.

Is AZEE 100 DT safe during pregnancy or breastfeeding?

AZEE 100 DT is primarily intended for use in children and adolescents aged 6 months to 18 years. It is generally not recommended for use in pregnant or breastfeeding women as there is limited safety data available for these groups, and it is contraindicated for use in pregnant and breastfeeding women. If prescribed, a doctor would weigh the benefits against the potential risks, and for breastfeeding mothers, they would advise to watch for symptoms like rashes, diarrhea, and sleepiness in the breastfed baby.

Can AZEE 100 DT be taken with other medications?

AZEE 100 DT can interact with certain medications. Antacids containing aluminum or magnesium may hinder the absorption of azithromycin. It may also interact with anticoagulants like warfarin, potentially increasing the risk of bleeding. Antiarrhythmics such as amiodarone and sotalol can interact with azithromycin, potentially leading to altered medicine effects or an increased risk of irregular heartbeats. Other macrolide antibiotics like erythromycin and clarithromycin can also interact, potentially increasing side effects. It's important to inform the doctor about all other medications being taken to avoid potential interactions.

What precautions should be taken with AZEE 100 DT?

Precautions should be taken if the patient has liver disease, as AZEE 100 DT could worsen the condition. Patients with kidney disease or heart problems (including abnormal heart rhythms or electrolyte imbalance) should also use this medicine cautiously and under a doctor's guidance. Individuals with Myasthenia Gravis should be monitored, as azithromycin could exacerbate this muscle disorder. It is recommended to avoid taking antacids simultaneously with AZEE 100 DT. Exposure to sunlight or tanning beds should also be avoided as it may increase the risk of sunburn.

What happens if a dose is missed?

If a dose of AZEE 100 DT is missed, it should be given as soon as remembered. However, if it is nearly time for the next scheduled dose, the missed dose should be skipped, and the regular dosing schedule should be continued. It is important not to give an extra dose to make up for a missed one without consulting a doctor.

How should AZEE 100 DT be stored?

AZEE 100 DT should be kept in a cool, dry place where the temperature stays below 30°C. It should be safeguarded from direct light and dampness. Always store this medication out of reach of children and pets. Ensure the medicine is used before its expiry date.