Pilorute Ep Cream 30g

PILORUTE EP CREAM 30G

Pilorute EP Cream 30G is a topical medication manufactured by Mankind-Futura, designed to provide relief from the symptoms associated with piles (hemorrhoids) and anal fissures.

Composition

Pilorute EP Cream contains a combination of active ingredients:

• Calcium Dobesilate (0.25% w/w): A vasoprotective agent that strengthens blood vessels, reduces leakage, and promotes healing.
• Hydrocortisone Acetate (0.25% w/w): A corticosteroid that decreases itching, inflammation, redness, and swelling.
• Lidocaine (Lignocaine) (3% w/w): A local anesthetic that blocks pain signals, providing temporary relief from pain and discomfort.
• Phenylephrine (0.1% w/w): A decongestant that shrinks swollen blood vessels, alleviating irritation and discomfort.
• Troxerutin (2% w/w): Improves blood flow and capillary function, reducing swelling and inflammation.
• Zinc Oxide: An astringent with antiseptic properties that helps reduce painful swelling, shrink hemorrhoids, and protect the skin from infection.

Uses

Pilorute EP Cream is primarily used for the treatment of:

• Piles (hemorrhoids), including grade 1 and 2 internal hemorrhoids, by shrinking blood vessels and relieving bleeding, itching, discomfort, and pain.
• Anal fissures, which are small tears in the lining of the anus, by reducing inflammation and promoting healing.
• Post-hemorrhoid removal surgery to aid healing and prevent recurrence.
• Proctitis (inflammation of the rectum lining) and painful evacuation.

Dosage and Administration

This medicine is for external use only.

• Clean and dry the affected area thoroughly before application.
• Wash hands before and after applying the cream.
• Apply a thin layer of the cream to the affected area, usually 2-3 times a day or as advised by your doctor.
• An applicator may be provided; if so, lubricate it and insert it 2-3 cm inside the anus for internal application.
• Avoid contact with eyes, ears, nose, or mouth. If accidental exposure occurs, rinse thoroughly with water and seek medical attention if necessary.
• Do not stop using it until the full course of treatment is finished, even if symptoms improve.

Side Effects

Common side effects are generally mild and temporary, occurring at the application site:

• Burning sensation
• Irritation
• Redness
• Itching

If these side effects persist or worsen, consult your doctor. Serious side effects are not commonly reported, but seek medical attention if severe reactions occur.

Precautions

• Hypersensitivity: Do not use if allergic to any of the ingredients.
• Pregnancy and Breastfeeding: Consult a doctor before use; generally, it should be used in pregnancy only if clearly necessary and with caution in breastfeeding women.
• Children: Not recommended for use in children under 12 years of age without consulting a doctor.
• Underlying Conditions: Use with caution in patients with lung, liver, or heart problems.
• Drug Interactions: Inform your doctor about all other medications being used, especially other numbing creams, certain laxatives, and medicines for chest pain, high blood pressure, cancer, infections, malaria, or fits.
• Avoid using with tuberculous or fungal lesions, skin vaccinia, varicella, and acute herpes simplex infection.

Storage

• Store at room temperature (below 25°C or 30°C), in a cool, dry place, away from heat, light, and moisture.
• Keep out of sight and reach of children and pets.
• Do not use after the expiration date.

What is Pilorute EP Cream used for?

Pilorute EP Cream is an anorectal preparation used to treat various conditions associated with discomfort in the anal area. It is primarily used for the treatment of piles (haemorrhoids), which are inflamed and swollen veins in the rectum and anus that cause pain, itching, and bleeding. It also treats anal fissures (small tears in the lining of the anus) and can provide symptomatic relief and support healing after haemorrhoid removal surgery, as well as manage proctitis (inflammation of the rectal lining) and painful evacuation.

How does Pilorute EP Cream work?

Pilorute EP Cream contains a combination of active ingredients that work together to alleviate symptoms. Calcium Dobesilate and Troxerutin are vasoprotective agents that strengthen blood vessel walls, reduce their permeability, decrease inflammation, improve blood circulation, and promote healing by reducing leakage from blood vessels. Hydrocortisone, a steroid, reduces itching, redness, and swelling. Lidocaine (also known as Lignocaine) is a local anaesthetic that blocks nerve pain signals, providing rapid relief from pain and itching. Phenylephrine acts as a decongestant and vasoconstrictor, shrinking swollen blood vessels to relieve swelling and irritation. Zinc Oxide has astringent, antiseptic, and protective properties, helping to soothe the area, prevent infection, and promote tissue healing.

What are the active ingredients in Pilorute EP Cream?

Pilorute EP Cream contains a combination of six active ingredients: Calcium Dobesilate (0.25% w/w), Hydrocortisone (0.25% w/w), Lidocaine (3% w/w), Phenylephrine (0.1% w/w), Troxerutin (2% w/w), and Zinc Oxide (5% w/w).

How should I apply Pilorute EP Cream?

Pilorute EP Cream is for external topical use only. Before application, ensure the affected area is clean and dry. Wash your hands thoroughly before and after use. Apply a thin layer of the cream over the affected area, usually 2-3 times a day or as directed by your physician. It's important to use the medicine regularly for the prescribed duration. Avoid getting the cream into your eyes, nose, or mouth. If accidental exposure occurs, rinse thoroughly with water and seek immediate medical attention.

What are the possible side effects of Pilorute EP Cream?

Pilorute EP Cream is generally well-tolerated. The most common side effects are usually temporary and occur at the application site, including a burning sensation, irritation, itching, and redness. If these symptoms persist or worsen, you should consult your doctor. In rare instances, consuming an excessive amount or accidental ingestion may lead to symptoms like nausea, dyspepsia, abdominal pain, or diarrhea.

Is Pilorute EP Cream safe during pregnancy or breastfeeding?

Information regarding the use of Pilorute EP Cream during pregnancy and breastfeeding is not fully established. It is crucial to consult your doctor before using this medicine if you are pregnant, planning a pregnancy, or breastfeeding. Your doctor will assess the potential risks and benefits.

Can Pilorute EP Cream be taken with other medications?

While drug interactions with topically applied Pilorute EP Cream are generally unlikely, it is important to inform your doctor about all other medications you are currently taking, including prescription, over-the-counter drugs, and herbal supplements. Caution is advised when using this cream concurrently with anticoagulant medications, as it has the potential to alter the coagulation profile. Additionally, avoid taking other laxatives without consulting your doctor, as some medications like iron tablets and antibiotics can cause constipation and might require a different approach.

What precautions should be taken while using Pilorute EP Cream?

Ensure the cream is for external use only and avoid contact with your eyes, nose, or mouth. Inform your doctor about any pre-existing medical conditions, especially liver or kidney diseases, or heart problems, as the cream should be used with caution in such cases. Do not use Pilorute EP Cream if you have a history of hypersensitivity or allergy to any of its ingredients. It is generally not recommended for use in children under 12 years of age, and should be used with caution in elderly patients. Also, do not cover the treated area with bandages or dressings unless specifically directed by your doctor.

What should I do if a dose is missed?

If you miss a dose of Pilorute EP Cream, apply it as soon as you remember. However, if it is almost time for your next scheduled application, skip the missed dose and continue with your regular dosing schedule. Do not apply a double dose to make up for the missed one.

How should Pilorute EP Cream be stored?

Pilorute EP Cream should be stored at room temperature, away from direct sunlight and heat. Keep it out of reach of children and pets.