Glyree 2 Mg Tablet (10 Tab)

GLYREE 2 MG TABLET

Name:

• Brand Name: Glyree 2 mg Tablet
• Common Name: Glimepiride (as the active ingredient)

Composition:

• Active Ingredients: Glimepiride 2 mg

Uses: Glyree 2 mg Tablet is an oral anti-diabetic medication used to manage Type 2 Diabetes Mellitus in adults. It is prescribed when diet and exercise alone are insufficient to control blood sugar levels. It helps by increasing insulin secretion from the pancreas and enhancing insulin sensitivity in the body's tissues, thereby lowering blood glucose. This medication helps prevent serious long-term complications associated with diabetes, such as kidney damage, blindness, nerve problems, and cardiovascular issues.

Dosage and Administration:

• Typically taken once daily with breakfast or the first main meal of the day.
• The recommended starting dose is usually 1 mg or 2 mg once daily.
• Dosage may be adjusted by a healthcare professional based on individual blood glucose levels, with a usual maintenance dose of 1–4 mg once daily and a maximum recommended dose of 8 mg once daily.
• Tablets should be swallowed whole with water and not chewed or crushed.
• It is crucial to take the medicine regularly at the same time each day and not to stop without consulting a doctor. Skipping meals while on this medication should be avoided.

Side Effects:

• Common Side Effects: Low blood sugar levels (hypoglycemia), nausea, dizziness, headache, weakness, and weight gain.
• Serious Side Effects: Severe allergic reactions (skin rash, swelling, difficulty breathing), liver problems (jaundice, hepatitis), and increased skin sensitivity to sunlight. Signs of hypoglycemia like sweating, shaking, confusion, or increased heartbeat should be addressed immediately, often by consuming sugary food or drink.

Precautions:

• Inform your doctor if you have allergies to glimepiride, sulfonylureas, or sulfonamides, or if you have Type 1 diabetes, severe kidney or liver disease, G6PD deficiency, or hormonal problems.
• Not recommended during pregnancy or breastfeeding; consult a doctor for alternatives like insulin therapy.
• Alcohol consumption should be limited or avoided as it can increase the risk of low blood sugar.
• Caution is advised when driving or operating machinery due to the risk of hypoglycemia-induced drowsiness or confusion.
• Inform your doctor about all other medicines and supplements being taken, as some can interact with Glyree 2 mg Tablet and affect blood glucose levels.

Storage:

• Store at room temperature in the original package, ideally between 15-25 °C or below 30 °C.
• Keep away from direct heat, light, and moisture.
• Keep out of sight and reach of children.

What is GLYREE 2 MG Tablet used for?

GLYREE 2 MG Tablet is an oral anti-diabetic medicine primarily used to manage Type 2 Diabetes Mellitus in adults. It helps to lower blood sugar levels when diet and exercise alone are not sufficient. It can be used by itself or in combination with insulin or other anti-diabetic medications to achieve better blood sugar control and prevent long-term complications like kidney damage, blindness, nerve problems, and cardiovascular issues.

How does GLYREE 2 MG Tablet work?

GLYREE 2 MG Tablet contains Glimepiride, which belongs to the sulfonylurea class of anti-diabetic agents. It works by stimulating the pancreas to release more insulin. Additionally, it enhances the body's sensitivity to insulin, which helps in the uptake and utilization of glucose from the bloodstream, thereby lowering blood sugar levels.

What is the usual dosage of GLYREE 2 MG Tablet?

The recommended starting dose for GLYREE 2 MG Tablet is typically 1 mg or 2 mg once daily, usually taken with breakfast or the first meal of the day. The dosage may be adjusted by your doctor based on your blood sugar levels and how you respond to the medicine. The usual maintenance dose ranges from 1–4 mg once daily, with a maximum recommended dose of 8 mg once daily. It's crucial to take it exactly as prescribed by your doctor and not to take it on an empty stomach.

What are the possible side effects of GLYREE 2 MG Tablet?

The most common side effect of GLYREE 2 MG Tablet is hypoglycemia (low blood sugar levels), which can manifest as sweating, dizziness, headache, shaking, weakness, increased hunger, and confusion. Other common side effects may include nausea, headache, dizziness, and weight gain. In some cases, increased skin sensitivity to sunlight may occur. Severe allergic reactions, liver problems (like jaundice), and a sudden drop in blood pressure are rare but serious side effects. If you experience symptoms of low blood sugar, it is advised to consume a quick-acting source of glucose like sugary food or fruit juice.

Is GLYREE 2 MG Tablet safe during pregnancy or breastfeeding?

GLYREE 2 MG Tablet is generally not recommended during pregnancy as it may harm the unborn baby. Your doctor may switch you to insulin therapy if you are pregnant or planning to conceive. For breastfeeding mothers, it is probably unsafe to use as the drug may pass into breast milk and could potentially cause low blood sugar in the infant. Always consult your doctor to discuss the risks and benefits before using this medicine if you are pregnant or breastfeeding.

Can GLYREE 2 MG Tablet be taken with other medications?

GLYREE 2 MG Tablet can interact with various medications, potentially leading to a drastic fall or increase in blood glucose levels.

• Medicines that can cause a drastic fall in blood glucose: Other antidiabetic medicines (like metformin, insulin), fluconazole, aspirin, warfarin, ramipril, lisinopril, and allopurinol.
• Medicines that can increase blood glucose: Estrogens, progestogens, diuretics, levothyroxine, rifampicin, glucocorticoids, and chlorpromazine.
• Other interactions: Caution is advised with corticosteroids, thyroid medicines, antifungals, certain pain relievers (like ibuprofen), and oral contraceptives. Always inform your doctor about all the medicines, supplements, or herbal products you are currently taking to avoid potential interactions.

What precautions should be taken with GLYREE 2 MG Tablet?

Several precautions should be taken while using GLYREE 2 MG Tablet:

• Hypoglycemia: Be aware of the signs of low blood sugar and carry a sugary snack or drink.
• Kidney and Liver Disease: Use with caution if you have kidney or liver problems, as dosage adjustments may be necessary. It is generally not recommended for severe kidney or liver disease.
• Alcohol Consumption: Limit or avoid alcohol as it can interfere with blood sugar control and increase the risk of low blood sugar.
• Sun Sensitivity: This medicine can make your skin more sensitive to sunlight, so use sunscreen or wear protective clothing.
• Stressful Conditions: Discontinue use if you are under stressful conditions like fever, trauma, surgeries, or accidents, as it may not be effective.
• G6PD Deficiency: Avoid if you have G6PD deficiency or hemolytic anemia, as it can worsen the condition.
• Type 1 Diabetes: Not recommended for Type 1 Diabetes Mellitus.
• Driving: Be cautious while driving or operating machinery, as fluctuations in blood sugar can affect alertness.

What happens if a dose of GLYREE 2 MG Tablet is missed?

If you miss a dose of GLYREE 2 MG Tablet, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to compensate for the missed one.

How should GLYREE 2 MG Tablet be stored?

GLYREE 2 MG Tablet should be stored at room temperature, ideally between 15-25 °C or below 30°C, in its original package. Keep the medicine away from direct heat, light, and moisture. Always ensure it is out of the reach of children. Do not use the medicine beyond its expiry date.