Mahagaba Nt 75 Mg Tablet (10 Tab)

MAHAGABA NT 75 MG TABLET (10 TAB)

MAHAGABA NT 75 MG TABLET is a combination medication manufactured by Mankind Pharma Ltd..

• Composition: Each tablet contains Pregabalin 75 mg and Nortriptyline 10 mg. Pregabalin is an anticonvulsant, and Nortriptyline is a tricyclic antidepressant.
• Uses: This medicine is primarily prescribed for the management of neuropathic pain. This includes pain arising from nerve damage due to conditions such as diabetic peripheral neuropathy, postherpetic neuralgia (shingles), and spinal cord injury. It may also be used for fibromyalgia and sciatic pain, and can help with associated symptoms like mood changes, sleep problems, and tiredness. Some sources also indicate its use as an adjunct therapy for partial seizures.
• Dosage and Administration: MAHAGABA NT 75 MG TABLET should be taken orally, with or without food, as directed by your doctor. It is often advised to take it at the same time each day, preferably at bedtime, to maintain a consistent level of medicine in the blood. Do not crush, break, or chew the tablet. It is crucial not to stop taking this medicine suddenly without consulting a doctor, as this may worsen symptoms or lead to withdrawal effects.
• Side Effects: Common side effects may include dizziness, sleepiness/drowsiness, dry mouth, blurred vision, constipation, increased appetite, and weight gain. Less common or rare side effects can include headache, nausea, vomiting, fatigue, uncoordinated body movements, difficulty passing urine, swelling of hands and feet (peripheral edema), memory problems, confusion, changes in mood or behavior, and suicidal thoughts. If any side effects persist or worsen, consult your doctor promptly.
• Precautions:
  • Pregnancy and Breastfeeding: It is generally not recommended for use during pregnancy or breastfeeding unless considered clearly necessary and advised by a doctor.
  • Alcohol: Avoid alcohol consumption as it can increase drowsiness and other side effects.
  • Driving and Machinery: Due to potential dizziness and sleepiness, do not drive or operate machinery until you know how the medicine affects you.
  • Medical Conditions: Inform your doctor about any history of kidney or liver problems, heart conditions, mental health disorders (including bipolar disorder or depression), or glaucoma.
  • Drug Interactions: Discuss all medications, including other antidepressants, antipsychotics, sympathomimetic agents, and certain blood pressure medicines, with your doctor to avoid potential interactions. Avoid MAO inhibitors within 14 days of taking this medicine.
  • Children and Elderly: MAHAGABA NT 75 MG TABLET is not recommended for children below 6 years of age. Use with caution in elderly patients due to an increased risk of side effects.
  • Suicidal Thoughts: This medicine can increase the risk of suicidal thoughts and behavior in some individuals; seek immediate medical advice if such signs emerge.
• Storage: Store below 30°C, away from moisture and heat. Keep out of reach of children.

What is MAHAGABA NT 75 MG TABLET used for?

MAHAGABA NT 75 MG TABLET is primarily used to treat neuropathic pain, which is pain caused by nerve damage. This can include conditions such as diabetic peripheral neuropathy, postherpetic neuralgia (nerve pain after shingles), pain due to spinal cord injury, fibromyalgia, and sciatic nerve pain. It may also be used in the management of seizures.

How does MAHAGABA NT 75 MG TABLET work?

This medicine is a combination of two active ingredients: Pregabalin and Nortriptyline. Pregabalin is an anticonvulsant that works by affecting chemicals in the brain that send pain signals across the nervous system and by modulating calcium channel activity in nerve cells. Nortriptyline is a tricyclic antidepressant that increases the levels of certain chemical messengers (serotonin and noradrenaline) in the brain, which helps to reduce pain messages reaching the brain and can also improve mood. Together, they effectively relieve neuropathic pain.

What is the usual dosage for MAHAGABA NT 75 MG TABLET?

MAHAGABA NT 75 MG TABLET should be taken exactly as prescribed by your doctor. It can be taken with or without food, preferably at the same time each day to maintain a consistent level of the medicine in your blood. The tablet should be swallowed whole with a glass of water; do not crush, break, or chew it. Your doctor will determine the correct dose and duration based on your condition.

What are the possible side effects of MAHAGABA NT 75 MG TABLET?

Common side effects may include dizziness, sleepiness or drowsiness, nausea, dry mouth, blurred vision, peripheral oedema (swelling of hands and feet), weight gain, constipation, and headache. Other possible side effects can include increased appetite, confusion, insomnia, decreased sex drive, tremor, and memory impairment. More serious but less common side effects can include suicidal thoughts or allergic reactions (such as swelling of the face or tongue, or skin redness with blisters). If you experience any severe or persistent side effects, or unusual changes in mood or behavior, you should consult your doctor immediately.

Is MAHAGABA NT 75 MG TABLET safe during pregnancy or breastfeeding?

MAHAGABA NT 75 MG TABLET is generally not recommended for use during pregnancy or by women of childbearing age unless considered clearly necessary by a doctor, as there is limited information on its safety in humans, and animal studies have shown potential harmful effects on the developing baby. Similarly, it is not recommended during breastfeeding because the drug may pass into breast milk and could harm the baby. Always consult your doctor to weigh the benefits and potential risks before taking this medication if you are pregnant, planning pregnancy, or breastfeeding.

Can MAHAGABA NT 75 MG TABLET be taken with other medications?

It is crucial to inform your doctor about all medications, supplements, and herbal products you are currently taking or plan to take to avoid potential drug interactions. MAHAGABA NT 75 MG TABLET should not be taken with MAO inhibitors (a type of antidepressant) within 14 days of use. Interactions can also occur with other antidepressants, antipsychotics, sympathomimetic agents (like ephedrine), certain blood pressure medications, medicines for irregular heartbeat, epilepsy medications (e.g., valproic acid, carbamazepine), anxiety medications (e.g., barbiturates), cimetidine, oxycodone, and ketamine.

What precautions should be taken while using MAHAGABA NT 75 MG TABLET?

Avoid consuming alcohol while taking this medicine as it can significantly increase dizziness and sleepiness. Since this medication can cause drowsiness and dizziness, do not drive or operate heavy machinery until you know how it affects you. It is not recommended for children as its safety and effectiveness have not been established. Use with caution if you have kidney or liver disease, heart problems, bipolar syndrome, or a history of seizures. Do not stop taking this medication abruptly without consulting your doctor, as this can lead to withdrawal symptoms. Also, be aware that it may cause weight gain and can make you more sensitive to sunburns, so use protective clothing and sunscreen outdoors.

What happens if a dose of MAHAGABA NT 75 MG TABLET is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one, as this can increase the risk of side effects. Missing a dose may also lead to a rise in blood pressure.

How should MAHAGABA NT 75 MG TABLET be stored?

MAHAGABA NT 75 MG TABLET should be stored at room temperature (20-25°C), away from moisture and heat. Keep this medicine out of the reach and sight of children and pets.