Valera 5 Mg Tablet

VALERA 5 MG TABLET

Name:

• Brand Name: Valera 5 MG Tablet
• Common Name: Evogliptin Tartrate (equivalent to Evogliptin 5 mg)

Composition: Each film-coated tablet contains Evogliptin Tartrate equivalent to 5 mg of Evogliptin. Valera 5 MG Tablet is a dipeptidyl peptidase-4 (DPP-4) inhibitor.

Uses: Valera 5 MG Tablet is prescribed for the management of Type 2 Diabetes Mellitus (T2DM) in adults. It is used as an adjunct to diet and exercise to improve glycemic control. It can be used as a monotherapy or in combination with other anti-diabetic medications such as metformin. The medicine works by increasing insulin secretion after meals and decreasing the production of hormones that raise blood sugar levels, thereby regulating post-meal blood glucose levels and reducing fasting blood sugar. This helps prevent serious complications of diabetes like kidney damage, blindness, and nerve damage.

Dosage and Administration: The typical adult dosage is one 5 mg film-coated tablet taken orally once daily. It can be taken with or without food, but it is recommended to take it at the same time each day for consistent effectiveness. The tablet should be swallowed whole with a glass of water and not crushed, chewed, or broken. Do not discontinue the medication without consulting your doctor.

Side Effects: Common side effects may include:

• Hypoglycemia (low blood sugar), especially when used with insulin or sulfonylurea.
• Abdominal pain, indigestion, gastritis.
• Diarrhea, nausea, vomiting.
• Common cold (nasopharyngitis), upper respiratory tract infection.
• Headache, dizziness, fatigue.
• Itching.
• Joint pain.
• Toothache. Less common but serious side effects can include pancreatitis and allergic reactions.

Precautions:

• Contraindications: Do not take Valera 5 MG Tablet if you are allergic to Evogliptin or any of its ingredients. It is not recommended for patients with Type 1 Diabetes Mellitus, severe ketosis, diabetic coma, or pre-coma. It is also not recommended for patients with severe renal impairment or end-stage renal disease requiring dialysis due to limited clinical data.
• Specific Conditions: Caution is advised for patients with liver issues, especially severe liver disease, as clinical data is limited. Exercise caution in patients with kidney conditions, and dose adjustment may be necessary. Inform your doctor if you have a history of heart failure or acute pancreatitis.
• Pregnancy and Breastfeeding: Valera 5 MG Tablet is generally not recommended during pregnancy or breastfeeding. Consult your doctor if you are pregnant, planning to become pregnant, or are breastfeeding.
• Drug Interactions: Inform your doctor about all prescribed and over-the-counter medications, herbal products, and supplements you are taking. Interactions can occur with certain antibiotics (e.g., clarithromycin, rifampicin) and other antidiabetic medications (e.g., metformin, sulfonylureas, insulin), potentially increasing the risk of hypoglycemia.
• Alcohol: While alcohol is not known to directly interact with Valera Tablet, it can affect blood sugar levels, so it's advisable to avoid it.
• Pediatric and Elderly Use: Safety and efficacy have not been established in children. Caution is advised for patients over 65 years due to limited safety data.

Storage: Keep Valera 5 MG Tablet out of the sight and reach of children. Store the medicine below 25°C and do not freeze it.

What is VALERA 5 MG TABLET used for?

VALERA 5 MG TABLET is primarily used to manage Type 2 Diabetes Mellitus (T2DM). It is prescribed for adults to help control high blood sugar levels, often in conjunction with a healthy diet and regular exercise. It can be used alone or in combination with other antidiabetic medications like metformin.

How does VALERA 5 MG TABLET work?

VALERA 5 MG TABLET contains Evogliptin, which belongs to a class of medicines called dipeptidyl peptidase-4 (DPP-4) inhibitors. It works by increasing the release of insulin from the pancreas after meals and decreasing the amount of glucagon, a hormone that raises blood sugar levels. This mechanism helps to regulate post-meal blood glucose and maintain stable blood sugar levels.

What is the usual dosage for VALERA 5 MG TABLET?

The usual adult dosage for VALERA 5 MG TABLET is 5 mg of Evogliptin, administered orally once daily. Your doctor will determine the correct dosage and frequency based on your health condition and blood sugar levels.

What are the possible side effects of VALERA 5 MG TABLET?

Common side effects can include hypoglycemia (low blood sugar), abdominal pain, indigestion, diarrhea, common cold, itching, nausea, vomiting, headache, dizziness, fatigue, nasopharyngitis, gastritis, and joint pain. Serious side effects, though rare, can include pancreatitis and heart failure. If you experience any severe or persistent side effects, you should consult your doctor.

Is VALERA 5 MG TABLET safe during pregnancy or breastfeeding?

VALERA 5 MG TABLET is generally not recommended during pregnancy, and caution is advised. Limited human data are available, and animal studies have shown potential harmful effects on the developing baby. Similarly, it is not recommended during breastfeeding as limited human data suggest the drug may pass into breast milk and could harm the baby. Always consult your doctor if you are pregnant, planning a pregnancy, or breastfeeding.

Can VALERA 5 MG TABLET be taken with other medications?

VALERA 5 MG TABLET can be safely combined with other antidiabetic medications such as metformin, pioglitazone, and glimepiride, as advised by your doctor. However, certain antibiotics like clarithromycin and rifampicin might interact with Valera Tablet, potentially affecting its efficacy or increasing the risk of side effects. It is crucial to inform your doctor about all prescribed and over-the-counter medications, as well as any herbal products or supplements you are taking, to avoid harmful interactions.

What precautions should be taken while taking VALERA 5 MG TABLET?

VALERA 5 MG TABLET is not recommended for individuals with Type 1 Diabetes Mellitus, diabetic ketoacidosis, severe renal impairment, or end-stage renal disease requiring dialysis. It should also be avoided if you are allergic to Evogliptin or any of its ingredients. Use with caution if you have liver issues, heart problems, or a history of acute pancreatitis. Maintaining a healthy diet and regular exercise is important while taking this medicine. Limiting alcohol intake is also advisable as it can increase the risk of low blood sugar.

What happens if a dose of VALERA 5 MG TABLET is missed?

If you miss a dose of VALERA 5 MG TABLET, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

How should VALERA 5 MG TABLET be stored?

VALERA 5 MG TABLET should be stored in a cool, dry place, ideally below 30°C, and kept out of the sight and reach of children and pets. It should not be frozen. Always check the expiry date before consuming the medicine.