Insugen R 40 Iu Inj 10 Ml (vial)

INSUGEN R 40 IU INJ 10 ML (VIAL) by BIOCON BIOLOGICS LIMITED is a fast-acting insulin used to manage diabetes mellitus. It works by mimicking human insulin to help the body utilize glucose for energy, thereby ensuring rapid and consistent blood sugar control.

Name

• Brand Name: INSUGEN R 40 IU INJ 10 ML (VIAL)
• Common Name: Human Insulin/Soluble Insulin (short-acting insulin)

Composition

• Active Ingredients: Human Insulin/Soluble Insulin (40 IU)
• Preservative: M Cresol (0.25%)

Uses

INSUGEN R 40 IU INJ is prescribed for the treatment of diabetes mellitus in both adults and children (above two years of age). It is used for both Type 1 and Type 2 diabetes to regulate blood glucose levels. This medication helps manage post-meal blood sugar spikes and reduces the risk of serious diabetes complications such as kidney damage, nerve problems, and vision loss.

Dosage and Administration

This medicine is administered via subcutaneous injection (under the skin) in areas like the upper thigh, abdomen, upper arm, or buttocks. It should be injected into a lifted skin fold, approximately 20 to 30 minutes before a meal. The injection site should be rotated to prevent skin irritation or lipodystrophy. Dosage and frequency are determined by a healthcare professional based on individual blood sugar levels and therapeutic response. It should not be administered intravenously, except in specific medical situations under supervision.

Side Effects

Common side effects include:

• Hypoglycemia (low blood sugar levels), which can manifest as sweating, rapid heartbeat, weakness, blurred vision, headache, anxiety, shakiness, hunger, and nervousness.
• Injection site reactions such as pain, redness, itching, swelling, or thickening of the skin.
• Weight gain.
• Edema (tissue swelling or fluid overload).
• Lipodystrophy (abnormal changes in fat tissue under the skin at the injection site).
• Decreased potassium levels (hypokalemia).

Precautions

• Do not use if experiencing hypoglycemia (low blood sugar).
• Inform your doctor if you have kidney, liver, or heart problems, or a history of stroke.
• Caution is advised with alcohol consumption as it can affect blood glucose levels.
• Insulin requirements may change during pregnancy and breastfeeding, so consult a doctor.
• Driving or operating machinery should be done with caution, as blood sugar fluctuations can affect concentration and reaction time.
• Do not stop taking the medicine without consulting your doctor.
• Medications such as glucocorticoids, thyroid hormones, growth hormone, sympathomimetics, and other antidiabetic agents can interact with insulin, requiring dose adjustments.

Storage

Unopened vials of INSUGEN R 40 IU should be stored in a refrigerator between 2°C and 8°C. Do not freeze. Once opened, vials can be stored under 25°C (or at room temperature) away from direct heat and light and should be used within 4 weeks. Keep out of sight and reach of children.

INSUGEN R 40 IU INJ 10 ML (VIAL) by BIOCON BIOLOGICS LIMITED is a type of short-acting human insulin used to manage blood sugar levels in people with diabetes mellitus.

What is Insugen R used for?

Insugen R 40 IU Injection is primarily used for the treatment of diabetes mellitus, including both Type 1 and Type 2 diabetes, in adults and children over two years of age. It helps to regulate blood glucose levels, particularly controlling blood sugar spikes that occur after meals (postprandial blood sugar control). This medication helps prevent serious diabetes complications like kidney damage, eye damage (retinopathy), nerve damage (neuropathy), delayed wound healing, and diabetic foot ulcers.

How does Insugen R work?

Insugen R contains human insulin, a rapid-acting insulin analogue that mimics the insulin naturally produced by the human body. It works by ensuring quick and consistent sugar control. The insulin facilitates the uptake of glucose (sugar) from the blood into muscle and fat cells for energy, and it also suppresses the liver's production of sugar. It typically starts working within 30 minutes of injection and its effect can last up to 8 hours.

What is the usual dosage of Insugen R?

The dosage of Insugen R is individualized and determined by your doctor based on your blood sugar levels and therapeutic response. It is usually administered subcutaneously (under the skin) 20 to 30 minutes before a meal. Common injection sites include the thigh, stomach area (abdomen, preferably), buttocks, or upper arm. It is important to rotate injection sites to prevent skin changes like lipodystrophy.

What are the possible side effects of Insugen R?

The most common side effect is hypoglycemia (low blood sugar levels), which can manifest as cold sweats, anxiety, shakiness, hunger, fast heart rate, headache, and nervousness. Other common side effects include rash, allergic reactions at the injection site (redness, itching, pain, swelling), weight gain, edema (tissue swelling), and skin thickening at the injection site (lipodystrophy). Most of these side effects are temporary and resolve over time, but persistent side effects should be reported to your doctor.

Is Insugen R safe during pregnancy or breastfeeding?

Insugen R is generally considered safe for use during pregnancy if prescribed by a doctor. However, your insulin dose may need to be adjusted during pregnancy and after delivery, and regular monitoring of blood sugar levels is recommended. It can also be safely given to nursing mothers under the supervision of a physician.

Can Insugen R be taken with other medications?

Yes, Insugen R can be used alone or in combination with other diabetes medicines, such as long-acting insulin or oral diabetes medications. However, some medications can affect insulin requirements, either reducing or increasing them. It's crucial to inform your doctor about all medications you are taking, including over-the-counter drugs and herbal supplements, as interactions can occur with glucocorticoids, thyroid hormones, growth hormone, certain antidiabetic medications (like metformin and glimepiride), antibiotics, antidepressants, and blood pressure medications.

What precautions should be taken?

Do not use Insugen R if you have low blood sugar levels (hypoglycemia). Inform your doctor if you have kidney, liver, or heart problems, or low blood potassium levels (hypokalaemia), as dose adjustments may be needed. Avoid consuming alcohol, as it can significantly affect blood sugar levels. Drive with caution, as fluctuations in blood sugar can affect your ability to concentrate and react. Always rotate injection sites to prevent lipodystrophy. Do not stop taking Insugen R without consulting your doctor.

What happens if a dose is missed?

If a dose of Insugen R is missed, your blood sugar levels may become too high (hyperglycemia). Take the missed dose as soon as you remember. However, if it's close to the time for your next scheduled dose, skip the missed dose and continue with your regular schedule; do not double the dose to compensate. It's important to discuss a plan with your doctor regarding missed doses. Regular monitoring of blood glucose levels is crucial.

How should Insugen R be stored?

Unopened vials of Insugen R should be stored in a refrigerator at a temperature between 2°C and 8°C. It is crucial not to freeze the medicine, and it should not be used if it has been frozen. Once opened or in use, vials can typically be kept at room temperature (below 30°C or between 15°C and 30°C) for up to 28 days (4 weeks); however, specific storage instructions on the product label should always be followed. Keep the medicine out of direct sunlight and away from heat.