Dapanova 5 Mg Tab

DAPANOVA 5 MG TABLET

DAPANOVA 5 MG TABLET is a medication primarily used for the management of Type 2 Diabetes Mellitus. It also plays a role in addressing certain cardiovascular and renal conditions.

• Name:

  • Brand Name: DAPANOVA 5 MG TABLET
  • Common Name: Dapagliflozin (5 mg)
  • Manufacturer: Medley Pharmaceuticals Ltd.

• Composition:

  • Each tablet contains Dapagliflozin 5 mg as the active ingredient. Dapagliflozin belongs to a class of medicines known as sodium-glucose co-transporter 2 (SGLT2) inhibitors.

• Uses: DAPANOVA 5 MG TABLET is prescribed for:

  • Type 2 Diabetes Mellitus: To enhance control of blood glucose levels in adults, often complementing diet and exercise. It can be used alone or in combination with other antidiabetic medications such as metformin, sulfonylureas, thiazolidinediones, DPP-4 inhibitors, and insulin. It works by removing excess sugar from the body via urine.
  • Heart Failure: To reduce the likelihood of hospitalization due to heart failure in adult patients, particularly those with type 2 diabetes and established cardiovascular disease or multiple risk factors. It helps lower the effort your heart needs to pump blood.
  • Chronic Kidney Disease: To manage chronic kidney disease in adults with reduced kidney function, helping to protect the kidneys from losing their function.

• Dosage and Administration:

  • DAPANOVA 5 MG TABLET should be taken as instructed by a doctor.
  • It is typically taken once daily, with or without food.
  • Swallow the tablet whole with a glass of water; do not crush, break, or chew it.
  • It is recommended to take the medicine at the same time each day for consistency.
  • The dosage may be adjusted by the doctor, potentially increasing up to 10 mg once daily, based on individual response and condition severity. Do not exceed the prescribed dosage without consulting a doctor.

• Side Effects:

  • Common Side Effects:
    • Urinary tract infections (UTIs)
    • Genital mycotic infections (yeast infections in the genital area)
    • Increased urination (polyuria) and painful or difficult urination (dysuria)
    • Back pain
    • Nasopharyngitis (inflammation of the nasal passages and throat, commonly known as a cold)
    • Dehydration and increased thirst
    • Dizziness
    • Skin rash
    • Constipation, dry mouth
  • Serious Side Effects (Seek medical attention if experienced):
    • Signs of an allergic reaction (skin rash, itching, swelling of the face, tongue, or throat, causing difficulty in breathing and swallowing).
    • Diabetic ketoacidosis (symptoms include nausea or vomiting, stomach pain, excessive thirst, fast and deep breathing, confusion, unusual sleepiness, a sweet smell to breath, or rapid weight loss).
    • Hypoglycemia (low blood sugar), especially when used with other antidiabetic medications or alcohol. Symptoms may include cold sweats, cool pale skin, tremors, and anxiety.

• Precautions:

  • Allergies: Do not take if allergic to Dapagliflozin or any other components of the tablet.
  • Medical Conditions: Inform your doctor if you have severe kidney disease, are on dialysis, have severe low blood pressure, severe dehydration, type 1 diabetes, liver disease, high blood ketone levels, or a history of urinary tract infections.
  • Pregnancy and Breastfeeding: DAPANOVA 5 MG TABLET is generally not recommended during pregnancy or while breastfeeding due to potential risks.
  • Alcohol Consumption: Caution is advised as alcohol can affect glucose levels and increase the risk of low blood sugar.
  • Drug Interactions: Inform your doctor about all medications, supplements, and herbal products you are taking, especially insulin or insulin secretagogues (e.g., glimepiride), UGT enzyme inducers (e.g., rifampin), diuretics, and certain heart medicines.
  • Hydration and Hygiene: Drink plenty of fluids to prevent dehydration and maintain good hygiene to reduce the risk of genital and urinary tract infections.
  • Monitoring: Regular monitoring of blood sugar levels and kidney function is crucial during treatment.
  • Driving: Your ability to drive may be affected by fluctuations in blood sugar levels.
  • Pediatric Use: Not recommended for children below 10 years for type 2 diabetes, or below 18 years for heart failure and kidney disease.
  • Elderly Patients: Use with caution in older patients (above 70 years) as they may be more susceptible to side effects.

• Storage:

  • Store in a cool and dry place, away from direct sunlight.
  • Keep out of sight and reach of children.
  • Typically stored at temperatures between 10ºC to 25ºC or below 30ºC.

Here are frequently asked questions about DAPANOVA 5 MG TAB (Dapagliflozin 5mg) by MEDLEY, along with concise answers:

What is DAPANOVA 5 MG TAB used for?

DAPANOVA 5 MG TAB is primarily used to manage type 2 diabetes mellitus in adults and children aged 10 years and older, especially when diet and exercise alone are not sufficient to control blood glucose levels. It is also used to treat heart failure and chronic kidney disease in adults, and can reduce the risk of hospitalization for heart failure in individuals with type 2 diabetes and cardiovascular disease or multiple cardiovascular risk factors.

How does DAPANOVA 5 MG TAB work?

DAPANOVA 5 MG TAB contains Dapagliflozin, which is a sodium-glucose cotransporter 2 (SGLT2) inhibitor. It works by blocking the action of the SGLT2 protein in the kidneys, which helps to prevent the reabsorption of glucose (blood sugar) back into the bloodstream. As a result, excess glucose is excreted from the body through urine, leading to lower blood sugar levels. This mechanism also helps to protect kidney function and reduce the strain on the heart.

What is the usual dosage for DAPANOVA 5 MG TAB?

For type 2 diabetes, the recommended starting dose for adults and children aged 10 and over is usually 5 mg once daily, which may be increased to 10 mg once daily for additional glycemic control. For heart failure or chronic kidney disease, the usual dose for adults is 10 mg once daily. It should be taken once a day, at the same time each day, with or without food.

What are the possible side effects of DAPANOVA 5 MG TAB?

Common side effects can include urinary tract infections (UTIs), genital yeast infections (thrush), increased urination, back pain, mild skin rash, and dizziness. Other potential side effects include feeling thirsty, nausea, and, rarely, vomiting. It can also cause low blood sugar (hypoglycemia), especially when taken with other diabetes medications like insulin. Serious but rare side effects include diabetic ketoacidosis (DKA) and necrotizing fasciitis of the perineum (Fournier's gangrene).

Is DAPANOVA 5 MG TAB safe during pregnancy or breastfeeding?

Dapagliflozin is generally not recommended during pregnancy, especially during the second and third trimesters, due to limited information and potential risks to the baby's developing kidneys observed in animal studies. For breastfeeding, it is also not usually recommended because it's unknown how much passes into breast milk and there's a theoretical risk of affecting the infant's sugar levels and kidney development. It is important to discuss with your doctor for alternative treatments if you are pregnant, planning to become pregnant, or breastfeeding.

Can DAPANOVA 5 MG TAB be taken with other medications?

Yes, DAPANOVA 5 MG TAB can be taken with other diabetes medications, including insulin and metformin, under medical supervision. However, if taken with insulin or sulfonylureas, the dose of these medications may need to be reduced to prevent low blood sugar. Caution is advised when taking it with diuretics, as it may increase the risk of dehydration and low blood pressure. It's advisable to inform your doctor about all medications and supplements you are taking.

What precautions should be taken with DAPANOVA 5 MG TAB?

It is important to monitor blood sugar levels regularly. If you experience severe nausea, vomiting, or diarrhea, or if you are unwell, consult your doctor as this can increase the risk of diabetic ketoacidosis (DKA). Be aware of symptoms of UTIs and genital infections, and seek medical advice if they occur. This medication may also cause dizziness, so use caution when standing up or driving. Inform your doctor if you have kidney or liver problems, or a history of DKA or urinary tract infections.

What happens if a dose of DAPANOVA 5 MG TAB is missed?

If you miss a dose, take it as soon as you remember, unless it's less than 12 hours until your next scheduled dose. In that case, skip the missed dose and take your next dose at the usual time. Do not take a double dose to make up for a forgotten one.

How should DAPANOVA 5 MG TAB be stored?

DAPANOVA 5 MG TAB should be stored at room temperature, away from excessive heat, moisture, and direct sunlight. Keep it in a secure location and out of the reach of children and pets. Unused or expired medication should be disposed of safely, ideally by returning it to a pharmacy.