Ozomet G1 Tab

OZOMET G1 TAB by OZONE PHARMACEUTICALS LTD.

OZOMET G1 TAB is a combination medication designed for the management of Type 2 Diabetes Mellitus. It works synergistically to help control high blood sugar levels when diet and exercise alone are not sufficient.

Name

• Brand Name: OZOMET G1 TAB, Ozomet-G1 Tablet, Ozomet G 1MG TABLET
• Manufacturer: OZONE PHARMACEUTICALS LTD.

Composition

OZOMET G1 TAB contains two active ingredients:

• Glimepiride (1mg): A sulfonylurea that stimulates the pancreas to release more insulin, thereby lowering blood glucose.
• Metformin (500mg): A biguanide that reduces glucose production in the liver, decreases the absorption of glucose from the intestines, and improves the body's sensitivity to insulin.

Uses

OZOMET G1 TAB is prescribed for:

• Managing Type 2 Diabetes Mellitus in adults.
• Controlling blood sugar levels when diet, exercise, or a single anti-diabetic agent (Glimepiride or Metformin) do not provide adequate glycemic control.
• Preventing long-term complications associated with diabetes, such as kidney damage, eye problems, and nerve issues.

Dosage and Administration

• OZOMET G1 TAB is taken orally, typically once or twice daily.
• It should be taken with meals, preferably with the evening meal or the first meal of the day, to minimize the risk of stomach upset.
• Tablets should be swallowed whole; do not crush, chew, or break them.
• The exact dosage is determined by a healthcare professional based on individual blood glucose levels and response to treatment.
• Consistent use, along with a healthy diet and regular exercise, is crucial for optimal results.

Side Effects

Common Side Effects:

• Hypoglycemia (low blood sugar), which can manifest as shakiness, sweating, dizziness, or confusion.
• Nausea, vomiting, diarrhea, abdominal pain, loss of appetite.
• Taste disturbance (often a metallic taste).
• Headache, dizziness, weakness, fatigue.
• Skin rash, itching.

Serious Side Effects (Seek immediate medical attention if experienced):

• Lactic acidosis, with symptoms like deep or rapid breathing, persistent nausea, vomiting, stomach pain, and severe tiredness.
• Severe allergic reactions (e.g., hives, increased sensitivity to sun, inflammation of blood vessels).
• Inflammation of the liver, which may lead to jaundice (yellowing of skin or eyes).
• Anemia, thrombocytopenia, agranulocytosis.

Precautions

• Contraindications: Not recommended for individuals with Type 1 Diabetes Mellitus, diabetic ketoacidosis, severe kidney or liver disease, dehydration, severe infections, or those who are pregnant or breastfeeding.
• Alcohol: Avoid alcohol consumption as it increases the risk of hypoglycemia and lactic acidosis.
• Interactions: Inform your doctor about all other medications, including over-the-counter drugs and herbal supplements, as they may interact with OZOMET G1 TAB. Certain antidiabetic agents, ACE inhibitors, and some antibiotics can increase the risk of hypoglycemia.
• Hypoglycemia: Patients should be aware of the symptoms of low blood sugar and carry a source of fast-acting sugar (e.g., glucose tablets or fruit juice).
• Sun Sensitivity: May increase skin sensitivity to the sun; use sunscreen when outdoors.
• Pediatric Use: Not suitable for children and adolescents under 18 years of age.
• Medical Conditions: Use with caution in patients with mild to moderate kidney or liver disease; dosage adjustments may be necessary.

Storage

• Store OZOMET G1 TAB in a cool, dry place.
• Keep it away from direct sunlight, moisture, and heat.
• Maintain a temperature between 20 to 25 degrees Celsius.
• Ensure it is kept out of reach of children and pets.

Here are the frequently asked questions (FAQs) about OZOMET G1 TAB by OZONE PHARMACEUTICALS LTD.

What is OZOMET G1 TAB used for?

OZOMET G1 TAB is a combination medication primarily used to manage type 2 diabetes mellitus in adults. It is prescribed when diet and exercise alone, or glimepiride or metformin used individually, are not sufficient to adequately control blood sugar levels. It helps improve glycemic control and can prevent long-term complications of diabetes such as kidney damage, nerve problems, and vision loss.

How does OZOMET G1 TAB work?

OZOMET G1 TAB contains two active ingredients: Glimepiride and Metformin. Glimepiride, a sulfonylurea, works by stimulating the beta cells in the pancreas to release more insulin. Insulin is crucial for moving sugar from the blood into cells. Metformin, a biguanide, acts in several ways: it reduces the amount of glucose produced by the liver, decreases the absorption of glucose from the intestines, and improves the body's sensitivity to insulin, making it more effective at utilizing blood sugar. Together, these components work synergistically to lower blood sugar levels.

What is the usual dosage for OZOMET G1 TAB?

The recommended dosage of OZOMET G1 TAB varies based on individual patient needs, blood glucose levels, and response to treatment. It is typically taken orally, once or twice daily, preferably with meals to help reduce gastrointestinal side effects. The tablet should be swallowed whole and not crushed, chewed, or broken. Your doctor will determine the appropriate dose for you and it's crucial to follow their instructions precisely, without adjusting the dosage on your own.

What are the possible side effects of OZOMET G1 TAB?

Common side effects of OZOMET G1 TAB may include hypoglycemia (low blood sugar), nausea, vomiting, diarrhea, abdominal pain, headache, dizziness, and a metallic taste in the mouth. Hypoglycemia can manifest as shakiness, sweating, and confusion, and it's important to carry a source of fast-acting sugar to treat it. More serious but rare side effects can include lactic acidosis, especially in patients with kidney or liver problems, or those who consume excessive alcohol. If you experience any severe or persistent side effects, you should consult your doctor immediately.

Is OZOMET G1 TAB safe during pregnancy or breastfeeding?

OZOMET G1 TAB is generally not recommended for use during pregnancy as it may be unsafe and animal studies have shown harmful effects on the developing baby. Similarly, it is considered unsafe during breastfeeding, and data suggests it may cause toxicity to the infant. It is essential to consult your doctor if you are pregnant, planning a pregnancy, or breastfeeding before taking this medication.

Can OZOMET G1 TAB be taken with other medications?

OZOMET G1 TAB can interact with several other medications. For example, other antidiabetic agents like sulfonylureas or insulin may increase the risk of low blood sugar (hypoglycemia). Certain antibiotics, ACE inhibitors (like enalapril), blood thinners (like warfarin), and some anti-hypertensive medicines can also affect its efficacy or increase side effects. Always inform your doctor about all other medications, including over-the-counter drugs, supplements, and herbal remedies, you are currently taking to avoid potential interactions.

What precautions should be taken while on OZOMET G1 TAB?

It is crucial to adhere to a healthy diet and regular exercise regimen as part of your diabetes management plan while taking OZOMET G1 TAB. Regular monitoring of blood sugar levels is essential to assess the medication's effectiveness and allow for dosage adjustments. Avoid excessive alcohol consumption, as it can increase the risk of hypoglycemia and lactic acidosis. Caution is advised for patients with kidney or liver problems, and those with a history of lactic acidosis. OZOMET G1 TAB can also make skin more sensitive to the sun, so using sunscreen is recommended.

What happens if a dose of OZOMET G1 TAB is missed?

If you miss a dose of OZOMET G1 TAB, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to compensate for the missed one. Always consult your doctor if you are unsure what to do.

How should OZOMET G1 TAB be stored?

OZOMET G1 TAB should be stored in a cool, dry place, away from direct sunlight and moisture. The medicine should be kept at a temperature between 20°C and 25°C. Ensure it is kept out of the reach and sight of children.