Dapefy S 10/100 Mg (15 Tab )

DAPEFY S 10/100 MG Tablets

Name:

• Brand Name: Dapefy-S 10/100 MG
• Common Name: Dapagliflozin and Sitagliptin Tablets
• Manufacturer: SUN PHARMA LABORATORIES LTD.

Composition: Each tablet contains:

• Dapagliflozin: 10 mg (Sodium-Glucose Cotransporter 2 (SGLT2) inhibitor)
• Sitagliptin: 100 mg (Dipeptidyl Peptidase-4 (DPP-4) inhibitor)

Uses: DAPEFY S 10/100 MG is prescribed for the management of Type 2 Diabetes Mellitus in adults. It is used alongside diet and exercise to improve blood sugar control, particularly when other medications alone are insufficient. The medicine works by increasing glucose excretion through the kidneys and by enhancing natural incretin levels to stimulate insulin release and reduce glucose production by the liver. It also helps reduce the risk of cardiovascular events and can be used in adults with chronic kidney disease.

Dosage and Administration: This medicine should be taken orally, usually once daily, with or without food, ideally at the same time each day for optimal benefit. The dosage is determined by a healthcare professional based on the patient's medical condition and response to treatment. It is crucial not to exceed the prescribed dose or stop the medication abruptly without consulting a doctor.

Side Effects: Common side effects may include:

• Urinary tract infections (UTIs)
• Genital mycotic (fungal) infections
• Nasopharyngitis (sore throat, runny/stuffy nose)
• Headache, dizziness
• Nausea, vomiting, diarrhea, flatulence, constipation
• Joint pain (arthralgia), back pain
• Increased urination

Serious side effects, though rare, warrant immediate medical attention, such as symptoms of pancreatitis or severe allergic reactions. Hypoglycemia (low blood sugar) can occur, especially when combined with other antidiabetic drugs.

Precautions: DAPEFY S 10/100 MG is contraindicated in individuals with hypersensitivity to its active ingredients. It is not recommended for Type 1 diabetes or diabetic ketoacidosis. Caution is advised for patients with kidney, liver, or heart conditions. Alcohol consumption should be limited or avoided due to the increased risk of side effects like diabetic ketoacidosis. Pregnant and breastfeeding women should consult their doctor before use, as safety data is limited. This medicine is not recommended for children under 18 years. Patients should inform their doctor about all other medications, supplements, or herbal products they are taking to avoid potential drug interactions.

Storage: Store DAPEFY S 10/100 MG in a cool, dry place, away from direct sunlight and moisture, at room temperature (ideally below 30°C or between 20°C to 25°C). Keep out of the sight and reach of children and pets. Do not freeze.

Here are the most frequently asked questions about DAPEFY S 10/100 MG:

What is DAPEFY S 10/100 MG used for?

DAPEFY S 10/100 MG is used for the management of type 2 diabetes mellitus in adults. It is prescribed when blood sugar levels are not adequately controlled by metformin alone, or when metformin is not suitable. This medication helps lower elevated blood glucose and can reduce the risk of diabetes-related complications.

How does DAPEFY S 10/100 MG work?

This medicine contains two active ingredients: Sitagliptin (100 mg) and Dapagliflozin (10 mg). Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor that works by increasing the activity of certain chemicals in the body, which leads to increased insulin release after meals and a reduction in glucose produced by the liver. Dapagliflozin is a sodium-glucose co-transporter 2 (SGLT2) inhibitor that blocks a protein in the kidneys responsible for reabsorbing glucose back into the blood, thus causing excess sugar to be removed through the urine.

What is the usual dosage for DAPEFY S 10/100 MG?

DAPEFY S 10/100 MG is typically taken orally once daily, with or without food. It is recommended to take it at the same time each day for optimal benefits. Your doctor will determine the appropriate dosage based on your medical condition and response to treatment.

What are the possible side effects of DAPEFY S 10/100 MG?

Common side effects can include urinary tract infections, nasal congestion, sore throat, upper respiratory tract infections, headache, back pain, joint pain, nausea, diarrhea, dizziness, and genital fungal infections. If you experience severe side effects such as acute pancreatitis (severe and persistent stomach pain) or serious allergic reactions (rash, swelling of the face/tongue/lips), seek immediate medical attention.

Is DAPEFY S 10/100 MG safe during pregnancy or breastfeeding?

There is limited information on the use of DAPEFY S 10/100 MG in pregnant women, so it should generally be avoided during pregnancy unless clearly advised by your doctor after weighing the potential benefits and risks. It is not recommended during breastfeeding as it is unknown whether the medicine passes into breast milk.

Can DAPEFY S 10/100 MG be taken with other medications?

It is crucial to inform your doctor about all other medicines, herbal products, and supplements you are currently taking or plan to take. DAPEFY S 10/100 MG can interact with other medications, including insulin and insulin secretagogues (which may increase the risk of low blood sugar), diuretics (which can increase the risk of dehydration and low blood pressure), and certain antifungals (e.g., ketoconazole), antivirals (e.g., ritonavir), antibiotics (e.g., clarithromycin), and heart medications (e.g., digoxin).

What precautions should be taken while using DAPEFY S 10/100 MG?

Before starting this medication, inform your doctor if you have kidney or liver problems, a history of urinary tract infections, pancreatitis, or heart failure. It is advisable to avoid excessive alcohol consumption as it can impact blood sugar control and may increase the risk of diabetic ketoacidosis. Drink plenty of fluids to prevent dehydration. Regularly monitor your blood sugar levels as directed by your doctor. Do not stop taking the medicine abruptly, even if your blood sugar levels seem controlled, as this can lead to a rebound increase in blood sugar. Elderly patients should use this medication with caution due to a potentially higher risk of side effects. As dizziness can occur, exercise caution when driving or operating machinery.

What happens if a dose of DAPEFY S 10/100 MG is missed?

If you miss a dose of DAPEFY S 10/100 MG, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to compensate for the missed one.

How should DAPEFY S 10/100 MG be stored?

DAPEFY S 10/100 MG should be stored in a cool, dry place at room temperature, ideally below 30°C. Keep it away from direct sunlight, excessive heat, and moisture. Ensure the medicine is kept out of the sight and reach of children. Always use the medicine before its expiry date.