Trenaxa 500 Mg Tablet (10 Tab)

TRENAXA 500 MG TABLET

TRENAXA 500 MG TABLET, manufactured by Macleods Pharmaceuticals Ltd., is an antifibrinolytic medication used to manage and prevent excessive bleeding.

• Name:

  • Brand Name: Trenaxa 500 Tablet
  • Common Name: Tranexamic Acid Tablet

• Composition:

  • Each tablet contains 500 mg of Tranexamic Acid as the active ingredient. Tranexamic acid works by inhibiting the breakdown of blood clots, thereby helping to control abnormal bleeding.

• Uses: Trenaxa 500 Tablet is prescribed for the short-term treatment and prevention of excessive bleeding in various conditions, including:

  • Heavy menstrual bleeding (menorrhagia)
  • Nosebleeds (epistaxis)
  • Bleeding after tooth extractions, particularly in patients with hemophilia
  • Post-surgical bleeding (e.g., after prostate, bladder, or cervical operations)
  • Internal bleeding due to various conditions.
  • Hereditary angioneurotic edema.

• Dosage and Administration:

  • This medicine should be taken orally, exactly as advised by a doctor.
  • It can be taken with or without food.
  • The typical adult dose for local fibrinolysis is 2 to 3 tablets (1000 mg to 1500 mg) two to three times daily. For heavy periods, it may be 1 to 1.5 grams three to four times daily for 3-4 days, initiated when bleeding becomes profuse.
  • Do not chew, crush, or break the tablet.
  • The dose and duration of treatment are determined by the doctor based on the patient's condition.

• Side Effects:

  • Common Side Effects: Nausea, vomiting, diarrhea, stomach pain, headache, back pain, muscle cramps, and fatigue. Taking the tablet with food may help reduce stomach upset.
  • Serious Side Effects: Rarely, it may cause problems from blood clots (e.g., deep vein thrombosis, pulmonary embolism), vision changes, severe allergic reactions (rash, swelling of face/tongue/throat, difficulty breathing), or sudden dizziness/fainting. Seek immediate medical attention if these occur.

• Precautions:

  • Inform your doctor if you have a history of blood clots, kidney disease, severe renal impairment, bleeding in the brain (subarachnoid hemorrhage), color vision problems, or seizures.
  • Use with caution in pregnant or breastfeeding women; consult a doctor.
  • Avoid or limit alcohol consumption as it may increase drowsiness and dizziness.
  • Caution is advised when driving or operating machinery as it may cause dizziness or tiredness.
  • Inform your doctor about all medications, especially blood thinners (e.g., warfarin, heparin) and oral contraceptives, as they can interact with Trenaxa 500 Tablet and increase the risk of blood clots.

• Storage:

  • Store in a cool and dry place, away from direct sunlight and moisture.
  • Keep out of sight and reach of children.
  • Store below 30°C.

TRENAXA 500 MG TABLET contains tranexamic acid, an anti-fibrinolytic agent used to manage and prevent excessive bleeding in various medical conditions.

What is Trenaxa 500 MG Tablet used for?

Trenaxa 500 MG Tablet is primarily used to control and prevent abnormal or excessive bleeding. This includes heavy menstrual bleeding (menorrhagia), nosebleeds (epistaxis), bleeding after surgeries (such as prostate, bladder, or cervical surgery, and dental extractions in patients with hemophilia), and internal bleeding due to various conditions. It can also be used for bleeding associated with trauma and endometriosis.

How does Trenaxa 500 MG Tablet work?

Trenaxa 500 MG Tablet contains tranexamic acid, which works by regulating the breakdown of blood clots in the body. It inhibits the action of plasmin, an enzyme that is responsible for dissolving blood clots. By blocking plasmin, tranexamic acid helps to stabilize existing blood clots, thereby reducing and preventing excessive blood loss.

What is the usual dosage for Trenaxa 500 MG Tablet?

The dosage of Trenaxa 500 MG Tablet is determined by your doctor based on your specific medical condition and response to treatment. It is typically taken orally, with or without food, 2-3 times a day, or as prescribed. For heavy menstrual bleeding, a common adult dosage can be 1300 mg (two 650 mg tablets, or equivalent) three times a day for a maximum of 5 days during monthly menstruation. It's crucial to follow your doctor's instructions and not exceed the prescribed dose.

What are the possible side effects of Trenaxa 500 MG Tablet?

Common side effects may include nausea, vomiting, diarrhea, stomach pain or discomfort, headache, and muscle cramps or musculoskeletal pain. Less common or more serious side effects can include dizziness, fatigue, low blood pressure (hypotension), allergic reactions (skin rash, itching), and in rare cases, visual disturbances or eye discomfort. If you experience any severe or persistent side effects, especially vision problems, consult your doctor immediately.

Is Trenaxa 500 MG Tablet safe during pregnancy or breastfeeding?

During pregnancy, Trenaxa 500 MG Tablet should be used with caution and only if prescribed by your doctor, as there is limited information on its effects in human pregnancy. It is considered probably safe to use during breastfeeding, but close monitoring of the infant is required, and you should consult your doctor before use.

Can Trenaxa 500 MG Tablet be taken with other medications?

Trenaxa 500 MG Tablet can interact with certain medications. It should be used with caution if you are taking blood thinners (anticoagulants) like warfarin or heparin, as this combination might reduce the effectiveness of Trenaxa or increase the risk of bleeding. Taking it with birth control pills (oral contraceptives) may increase the risk of blood clot formation, including deep vein thrombosis. Inform your doctor about all medications and supplements you are currently taking.

What precautions should be taken with Trenaxa 500 MG Tablet?

Avoid using Trenaxa 500 MG Tablet if you have a history of blood clotting disorders, kidney disease, convulsions, or a history of stroke, unless specifically advised by your doctor. Inform your doctor about any pre-existing medical conditions, especially liver, kidney, or eye problems. Regular eye tests and blood tests may be advised to monitor for any vision problems or liver/kidney function issues. If you experience dizziness or changes in vision, avoid driving or operating machinery. Alcohol consumption should be avoided or limited as it may cause excessive drowsiness.

What happens if a dose of Trenaxa 500 MG Tablet is missed?

If you miss a dose of Trenaxa 500 MG Tablet, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to compensate for the missed one.

How should Trenaxa 500 MG Tablet be stored?

Trenaxa 500 MG Tablet should be stored in a cool and dry place, away from direct sunlight and moisture, and below 25°C or 30°C. Keep it out of sight and reach of children and pets.