Empahope S 10/100mg Tab

EMPAHOPE S 10/100MG TAB is a medication manufactured by MACLEODS PHARMACEUTICALS LTD, primarily used for the management of Type 2 Diabetes Mellitus.

Name

• Brand Name: EMPAHOPE S 10/100MG TAB
• Manufacturer: MACLEODS PHARMACEUTICALS LTD

Composition

Each tablet contains a combination of two active ingredients:

• Empagliflozin: 10mg
• Sitagliptin: 100mg

Uses

EMPAHOPE S 10/100MG TAB is prescribed for adults with Type 2 Diabetes Mellitus to help control high blood sugar levels. It is used when diet and exercise alone are insufficient to manage the condition. The medication works by two mechanisms: Empagliflozin helps the kidneys remove excess sugar from the body through urine, while Sitagliptin enhances the body's insulin production when blood sugar is high and reduces sugar production by the liver. This dual action supports better long-term diabetes management and helps reduce the risk of diabetes-related complications. It is not indicated for Type 1 Diabetes or diabetic ketoacidosis.

Dosage and Administration

The dosage should be taken as advised by a healthcare professional. It can be taken with or without food, preferably after meals or at a fixed time each day, ideally in the morning. Tablets should be swallowed whole and not chewed, crushed, or broken. Do not discontinue the medication without consulting your doctor, as this can lead to increased blood sugar levels. If a dose is missed, take it as soon as remembered, but skip it if it is almost time for the next scheduled dose to avoid taking a double dose.

Side Effects

Common side effects associated with EMPAHOPE S 10/100MG TAB may include:

• Urinary tract infections (UTIs)
• Upper respiratory tract infections
• Fungal infections (e.g., genital yeast infection)
• Headaches
• Low blood sugar (hypoglycemia), especially if taken with other diabetes medications
• Feeling thirsty
• Frequent urination
• Rash

Precautions

• Contraindications: Do not use if allergic to Empagliflozin, Sitagliptin, or any other ingredients. It is also contraindicated in patients with severe kidney or liver disease.
• Specific Conditions: Exercise caution in older adults and individuals at risk of dehydration (e.g., due to vomiting, diarrhea, fever, or concurrent use of diuretics or blood pressure-lowering medications). It is not recommended for patients with Type 1 Diabetes or those with a history of diabetic ketoacidosis.
• Drug Interactions: Inform your doctor about all medications, supplements, or herbal products you are currently taking, especially diuretics, insulin, sulfonylureas, lithium, blood pressure medications, heart failure medications, high cholesterol medications, blood thinners, anti-infectives, antihistamines, painkillers, immunomodulatory medicines, or medications for brain-related disorders.
• Pregnancy and Breastfeeding: EMPAHOPE S 10/100MG TAB may be unsafe during pregnancy and is not recommended for breastfeeding women due to potential harm to the unborn baby or infant. Consult a doctor.
• Alcohol: Consult your doctor regarding alcohol consumption as it may increase the risk of dizziness and hypoglycemia.

Storage

Store the medicine in a cool, dry place, below 30°C. Protect it from direct sunlight, moisture, and light. Keep out of reach of children and pets.

EMPAHOPE S 10/100MG TAB is a medication used to manage Type 2 Diabetes Mellitus. It combines two active ingredients, Empagliflozin (10mg) and Sitagliptin (100mg), which work together to help control blood sugar levels when diet and exercise alone are insufficient.

What is EMPAHOPE S 10/100MG TAB used for?

EMPAHOPE S 10/100MG TAB is primarily used to treat Type 2 Diabetes Mellitus in adults. It helps to lower and maintain blood sugar levels in conjunction with a healthy diet and regular exercise. The medication may also help reduce the risk of complications associated with high blood sugar and can offer cardiovascular and kidney health benefits. It is not recommended for Type 1 Diabetes Mellitus or diabetic ketoacidosis.

How does EMPAHOPE S 10/100MG TAB work?

This medicine works through a dual mechanism due to its two active components:

• Empagliflozin: This is an SGLT2 (sodium-glucose co-transporter 2) inhibitor. It works by blocking the SGLT2 protein in the kidneys, which leads to increased excretion of excess blood sugar through the urine, thereby lowering blood glucose levels.
• Sitagliptin: This is a DPP-4 (dipeptidyl peptidase-4) inhibitor. It works by increasing the production of insulin in the body after a meal and decreasing the amount of sugar produced by the liver. Together, these components provide comprehensive glucose control.

What is the usual dosage and how should it be taken?

The dosage of EMPAHOPE S 10/100MG TAB should be as advised by your doctor. It is typically taken once daily. The tablet should be swallowed whole with water, and it can be taken with or without food, preferably at the same time each day to maintain consistent blood sugar control. Do not chew, crush, or break the tablet.

What are the possible side effects of EMPAHOPE S 10/100MG TAB?

Common side effects may include urinary tract infections, fungal infections (especially genital), upper respiratory tract infections, headache, thirst, and frequent urination. Less common but serious side effects can include diabetic ketoacidosis or hypoglycemia (low blood sugar), especially when combined with insulin or sulfonylureas. If any side effects persist or worsen, consult your doctor.

Is EMPAHOPE S 10/100MG TAB safe during pregnancy or breastfeeding?

EMPAHOPE S 10/100MG TAB is generally considered unsafe during pregnancy as it can potentially harm the unborn baby. Similarly, it should not be used by breastfeeding women, as limited data suggests the drug may pass into breast milk and harm the baby. Always consult your doctor for safe alternative treatments if you are pregnant, planning a pregnancy, or breastfeeding.

Can it be taken with other medications?

It is crucial to inform your doctor about all medications, supplements, or herbal products you are currently taking or plan to take to avoid potential interactions. Special caution is advised if you are taking other medications for high blood pressure, heart failure, high cholesterol, blood thinners, anti-infectives, other antidiabetics (like insulin or sulfonylureas), or diuretics ("water pills"), as interactions can occur.

What precautions should be taken while using EMPAHOPE S 10/100MG TAB?

Exercise caution if you have a history of kidney or liver problems, urinary tract infections, or heart conditions. This medicine should be used with care in older adults and those who are dehydrated or on diuretics, as it may increase the risk of low blood pressure. Avoid excessive alcohol consumption, as it can lower blood sugar and increase the risk of lactic acidosis. It is not for Type 1 Diabetes and should not be stopped suddenly without consulting a doctor.

What happens if a dose is missed?

If you miss a dose, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to compensate for the missed one.

How should it be stored?

EMPAHOPE S 10/100MG TAB should be stored in a cool, dry place, below 30°C, away from direct sunlight. Keep it out of reach of children and pets.