Seroflo 125 Inhaler

SEROFLO 125 INHALER

Name:

• Brand Name: SEROFLO 125 INHALER
• Common Name: Salmeterol and Fluticasone Propionate Inhaler

Composition: SEROFLO 125 INHALER contains a combination of two active ingredients:

• Salmeterol (25 mcg per actuation)
• Fluticasone Propionate (125 mcg per actuation)

Salmeterol is a long-acting beta2-adrenergic agonist (LABA) that relaxes the muscles in the airways, widening them to make breathing easier. Fluticasone Propionate is a corticosteroid that reduces swelling and irritation in the lungs by stopping the release of certain chemicals that cause inflammation.

Uses: SEROFLO 125 INHALER is prescribed for the long-term management and prevention of symptoms associated with:

• Asthma (wheezing, coughing, shortness of breath, and chest tightness)
• Chronic Obstructive Pulmonary Disease (COPD), including chronic bronchitis (inflammation of the lining of your bronchial tubes) and emphysema (shortness of breath).

It is not intended for the immediate relief of sudden asthma attacks; a fast-acting "reliever" inhaler should be used for acute bronchospasms.

Dosage and Administration: The typical adult dosage for SEROFLO 125 INHALER is two inhalations (puffs) twice daily. It should be used regularly as directed by a doctor to be effective, even if symptoms are not present.

• Administration: For inhalation purposes only. Rinse your mouth with water and spit it out after each use to help prevent fungal infections in the mouth and throat.

Side Effects: Common side effects may include:

• Headache
• Hoarseness of voice and throat irritation
• Fungal infection of the mouth/oral candidiasis (thrush)
• Cough
• Nausea and vomiting
• Upper respiratory tract infection
• Muscle cramps or joint pain

Serious side effects like paradoxical bronchospasm (immediate worsening of breathing) may occur, requiring immediate medical attention and discontinuation of the inhaler.

Precautions:

• Allergies: Do not use if allergic to salmeterol, fluticasone propionate, or any other ingredients.
• Existing Conditions: Inform your doctor if you have heart problems (e.g., arrhythmias, hypertension), diabetes (may increase blood sugar levels), thyroid disorders, active infections (fungal, bacterial, or viral), or low blood potassium levels.
• Pregnancy and Breastfeeding: Consult a doctor if pregnant or breastfeeding.
• Children: SEROFLO 125 INHALER is generally not recommended for children under 12 years of age, and specifically not for children under 4 years.
• Monitoring: Regular eye check-ups may be recommended for long-term users due to potential risks of glaucoma or cataracts.
• Interactions: Use with caution alongside certain medications, including monoamine oxidase inhibitors, tricyclic antidepressants, beta-blockers, and diuretics, as they may increase the risk of side effects or reduce effectiveness.

Storage: Store SEROFLO 125 INHALER in a cool, dry place, ideally below 30°C. Protect it from direct sunlight, heat, and frost. Keep it out of reach of children and pets. Do not store in a cold place as it may not work effectively.

SEROFLO 125 Inhaler by Cipla Ltd. is a combination medication containing Salmeterol (25 mcg) and Fluticasone Propionate (125 mcg). It is primarily used for the regular treatment and control of respiratory conditions such as asthma and Chronic Obstructive Pulmonary Disease (COPD), including bronchitis and emphysema. This inhaler is not intended for immediate relief of sudden asthma attacks.

What is SEROFLO 125 Inhaler used for?

SEROFLO 125 Inhaler is prescribed for the long-term management and prevention of symptoms associated with asthma and Chronic Obstructive Pulmonary Disease (COPD). This includes conditions like chronic bronchitis and emphysema. It helps to relieve symptoms such as wheezing, coughing, shortness of breath, and chest tightness.

How does SEROFLO 125 Inhaler work?

This inhaler contains two active ingredients: Salmeterol and Fluticasone Propionate. Salmeterol is a long-acting bronchodilator that works by relaxing the muscles in the airways, thereby widening them and making breathing easier. Fluticasone Propionate is a corticosteroid that reduces inflammation (swelling and irritation) in the airways by stopping the release of certain chemicals that cause inflammatory reactions.

What is the usual dosage of SEROFLO 125 Inhaler?

The typical dosage for adults and children 12 years and older is two inhalations of 25 micrograms salmeterol and 125 micrograms fluticasone propionate twice daily. It should be used regularly at the same time each day, as advised by your doctor, for optimal results.

What are the possible side effects of SEROFLO 125 Inhaler?

Common side effects can include headache, stomach upset, dizziness, nervousness, vomiting, upper respiratory tract infection, fungal infection of the mouth (oral thrush), hoarseness of voice, sore throat, and cough. Muscle cramps, joint pain, and increased heart rate may also occur. Rinsing your mouth with water and spitting it out after each use can help prevent fungal infections. If side effects persist or worsen, consult your doctor.

Is SEROFLO 125 Inhaler safe during pregnancy or breastfeeding?

The safety of SEROFLO 125 Inhaler during pregnancy and breastfeeding is not fully established, and limited studies exist in humans. It is generally not recommended unless clearly necessary and the potential benefits outweigh the risks. You should inform your doctor if you are pregnant, planning a pregnancy, or breastfeeding to discuss the risks and benefits.

Can SEROFLO 125 Inhaler be taken with other medications?

SEROFLO 125 Inhaler can interact with certain medications. Concomitant use with beta-blockers (e.g., propranolol, atenolol) may reduce its effectiveness and can cause severe breathing problems. Diuretics ("water pills") may increase the risk of low potassium levels. Potent CYP3A4 inhibitors like ritonavir and ketoconazole (used for HIV and fungal infections, respectively) can significantly increase fluticasone levels, leading to potential side effects like Cushing's syndrome and adrenal suppression. Always inform your doctor about all medicines, supplements, or herbal products you are currently taking to avoid possible interactions.

What precautions should be taken with SEROFLO 125 Inhaler?

It's crucial to use the inhaler correctly and to maintain good oral hygiene by rinsing your mouth after each use to prevent fungal infections. Do not stop using the inhaler suddenly, even if your symptoms improve, as this can worsen your condition. Inform your doctor if you have heart problems, diabetes (as it may increase blood sugar levels), thyroid disorders, active infections, or low potassium levels in your blood. Regular monitoring of blood potassium levels is recommended.

What happens if a dose is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

How should SEROFLO 125 Inhaler be stored?

Store SEROFLO 125 Inhaler in a cool and dry place, ideally at room temperature below 30°C. Protect it from direct sunlight, heat, and frost. Do not store it in a cold place as it may not work as well. Keep it out of reach of children and pets.