Dynaglipt M Forte Tablet (10 Tab)

DYNAGLIPT M FORTE TABLET (10 TAB) by MANKIND PHARMA LTD.

Name: Dynaglipt M Forte Tablet, also known as Dynaglipt-M Forte Tablet SR.

Composition: Each tablet contains two active ingredients:

• Metformin Hydrochloride (1000 mg)
• Teneligliptin (20 mg)

Uses: Dynaglipt M Forte Tablet is primarily prescribed for the management of Type 2 Diabetes Mellitus in adults. It works to control high blood sugar levels by reducing glucose production in the liver, decreasing intestinal glucose absorption, and increasing insulin production and sensitivity. This helps prevent serious complications associated with diabetes, such as kidney damage, blindness, nerve issues, and may also reduce the risk of heart attack and stroke. It is used when diet and exercise alone, or other single antidiabetic agents, are not sufficient for glycemic control.

Dosage and Administration: This medicine should be taken orally as directed by a healthcare professional. It is typically advised to take the tablet with food to minimize stomach upset, usually once daily. Do not crush, chew, or break the tablet. The dosage may vary based on the patient's condition and response to treatment.

Side Effects:

• Common: Diarrhea, nausea, vomiting, indigestion, stomach discomfort/pain, headache, and hypoglycemia (low blood sugar levels).
• Serious: Rare but serious side effects can include lactic acidosis (buildup of lactic acid in the blood) and Vitamin B12 deficiency with long-term use. Pancreatitis is also a possible rare side effect.

Precautions:

• Medical Conditions: Exercise caution in patients with liver disease, kidney impairment, congestive heart failure, or metabolic acidosis.
• Alcohol: Avoid alcohol consumption as it may increase the risk of lactic acidosis.
• Pregnancy & Breastfeeding: Consult a doctor before use if pregnant or breastfeeding.
• Drug Interactions: Inform your doctor about all other medications being taken, especially insulin, sulfonylureas, carbonic anhydrase inhibitors, and medicines affecting renal function, as interactions can occur.
• Surgery: Inform your doctor if you are due to have surgery under general anesthetic.

Storage: Store Dynaglipt M Forte Tablet in a dry place below 30°C. Protect it from direct light and moisture, and keep it out of the sight and reach of children.

What is Dynaglipt M Forte Tablet used for?

Dynaglipt M Forte Tablet is primarily used to manage high blood sugar levels in adults with type 2 diabetes mellitus. It helps improve glycemic control and can prevent serious long-term complications associated with diabetes, such as kidney damage, blindness, nerve issues, limb amputations, and sexual dysfunction. Additionally, it may reduce the risk of heart attack and stroke.

How does Dynaglipt M Forte Tablet work?

Dynaglipt M Forte Tablet contains two active ingredients: Metformin (1000 mg) and Teneligliptin (20 mg). Metformin works by reducing glucose production in the liver and decreasing the absorption of glucose from the intestines. It also enhances insulin sensitivity, improving the body's use of insulin. Teneligliptin is a DPP-4 inhibitor that helps stabilize incretin hormones (GLP-1 and GIP), which are crucial for controlling blood sugar levels after meals. It achieves this by increasing insulin secretion and decreasing glucagon levels in the body.

What is the usual dosage of Dynaglipt M Forte Tablet?

The dosage of Dynaglipt M Forte Tablet is determined by your doctor based on your health condition and response to treatment. Typically, it is taken orally, usually once or twice daily with meals. It is crucial to follow your doctor's instructions and not to exceed the prescribed dose.

What are the possible side effects of Dynaglipt M Forte Tablet?

Common side effects may include diarrhea, nausea, vomiting, indigestion, stomach discomfort, headache, and hypoglycemia (low blood sugar levels), especially when taken with other antidiabetic medicines or if meals are missed. A rare but serious side effect is lactic acidosis, characterized by symptoms like deep and rapid breathing, persistent nausea, vomiting, and stomach pain, which requires immediate medical attention. Long-term use may also lead to Vitamin B12 deficiency, potentially causing anemia and nerve issues.

Is Dynaglipt M Forte Tablet safe during pregnancy or breastfeeding?

Caution is advised when taking Dynaglipt M Forte Tablet during pregnancy. It is generally not recommended, and consulting your doctor for safer alternatives is important. For breastfeeding mothers, it is probably unsafe as the drug may pass into breast milk and potentially harm the baby. Consult your doctor to understand the risks and benefits.

Can it be taken with other medications?

Dynaglipt M Forte Tablet can interact with various medications. For instance, medicines like ranolazine and carbonic anhydrase inhibitors (e.g., topiramate, acetazolamide) can increase the risk of lactic acidosis. Other antidiabetic medicines, insulin, certain antidepressants (e.g., phenelzine), blood pressure medications (e.g., atenolol), and steroids may also interact. Always inform your doctor about all medicines, including over-the-counter drugs, vitamins, and herbal supplements, to prevent potential interactions.

What precautions should be taken?

Several precautions should be observed. Avoid alcohol consumption as it increases the risk of lactic acidosis. Inform your doctor if you have liver, kidney, or heart disease, severe infection, or are undergoing surgery, as these conditions may affect the use of this medicine. Regular monitoring of blood sugar levels and kidney function is advisable during treatment.

What happens if a dose is missed?

If you miss a dose of Dynaglipt M Forte Tablet, take it as soon as you remember. However, if it's almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to compensate for the missed one.

How should it be stored?

Dynaglipt M Forte Tablet should be stored in a dry place at a temperature below 30 degrees Celsius, protected from direct light and moisture. Keep the medicine in its original container with the lid tightly closed and out of the reach of children. Always check the expiry date before taking the tablet.